3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 1,644 studies in Brain & Nervous System

[Pharmacologic correction of learning and memory disorders induced by exposure to high-frequency electromagnetic radiation].

Krylov IN, Iasnetsov VV, Dukhanin AS, Pal'tsev IuP · 1993

Russian researchers exposed rats to microwave radiation at 2375 MHz (similar to some WiFi frequencies) and found it caused retrograde amnesia - the inability to recall memories formed before the exposure. The memory loss involved multiple brain chemical systems including those that regulate mood and cognition. However, two drugs called piracetam and oxiracetam were able to prevent the memory damage when given before exposure.

The effect of pulsed microwaves on passive electrical properties and interspike intervals of snail neurons.

Field AS, Ginsburg K, Lin JC · 1993

Researchers exposed snail neurons to pulsed 2.45 GHz microwaves and found they caused significant changes to the neurons' electrical properties, specifically increasing their resistance to electrical current. These effects occurred without any temperature changes, proving the microwaves directly affected nerve cell function. This demonstrates that radiofrequency radiation can alter how neurons work at the cellular level.

Brain & Nervous SystemNo Effects Found

Modification of acoustic startle by microwave pulses in the rat: a preliminary report.

Seaman RL, Beblo DA · 1992

Researchers exposed rats to intense microwave pulses just before loud sounds to see if the microwaves affected their startle reflex. They found that moderate-intensity microwave pulses delayed and reduced the rats' startle responses, but surprisingly, higher-intensity pulses had no effect. This suggests that microwave radiation can interfere with nervous system responses, but the relationship isn't straightforward.

Brain & Nervous SystemNo Effects Found

Bursting responses of Lymnea neurons to microwave radiation.

Bolshakov MA, Alekseev SI · 1992

Researchers exposed pond snail neurons to 900 MHz microwave radiation to study effects on brain cell activity. They found that pulsed microwave signals at low power levels (0.5 W/kg SAR) caused sudden bursts of irregular firing in neurons, while continuous wave signals at the same power had no effect. This suggests that the pattern of microwave exposure, not just the power level, can alter how brain cells communicate.

Effects of hyperthermia induced by microwave irradiation on brain development in mice.

Fukui Y, Hoshino K, Inouye M, Kameyama Y · 1992

Japanese researchers exposed pregnant mice to 2.45 GHz microwave radiation (the same frequency used in microwave ovens and WiFi) during a critical brain development period. They found that 20 minutes of exposure caused brain damage, reduced brain weight, and altered brain cell density in developing offspring. The effects were similar to heating the animals in hot water, suggesting the damage came from the microwaves heating brain tissue.

[Effect of extremely high-frequency electromagnetic radiation on the function of skin sensory endings].

Enin LD, Akoev GN, Potekhina IL, Oleiner VD · 1992

Russian researchers exposed rat paw skin to millimeter wave radiation (55.61 and 73 GHz frequencies) and measured how nerve endings responded to touch. They found that this extremely high-frequency EMF significantly reduced skin sensitivity - half of the nerve receptors stopped responding to touch within 25 minutes of exposure, while others showed altered responses even after 35 minutes. The effects showed a strict frequency-specific pattern, suggesting the radiation directly interferes with how skin sensors communicate with the nervous system.

Dose dependence of acetylcholinesterase activity in neuroblastoma cells exposed to modulated radio-frequency electromagnetic radiation.

Dutta SK, Das K, Ghosh B, Blackman CF · 1992

Researchers exposed neuroblastoma brain cells to 147-MHz radio frequency radiation (similar to frequencies used in wireless devices) for 30 minutes and found it increased activity of acetylcholinesterase, a key enzyme involved in brain cell communication. The effect only occurred at specific power levels that had previously been shown to disrupt calcium release in the same type of cells. This suggests that RF radiation can interfere with fundamental brain cell processes that control neurotransmitter function.

Naltrexone-sensitive analgesia following exposure of mice to 2450-MHz radiofrequency radiation

Maillefer RH, Quock RM · 1992

Researchers exposed mice to microwave radiation at 2450 MHz (the same frequency used in microwave ovens) for 10 minutes and measured their pain response. They found that higher radiation levels caused the mice's bodies to heat up and triggered natural pain-killing mechanisms in the brain, similar to how the body responds to other forms of thermal stress. This suggests that microwave radiation can cause biological effects beyond just heating tissue.

Single vs. repeated microwave exposure: effects on benzodiazepine receptors in the brain of the rat.

Lai H, Carino MA, Horita A, Guy AW · 1992

Researchers exposed rats to microwave radiation (2450 MHz) for 45 minutes and measured changes in brain receptors that respond to anxiety and stress. A single exposure increased these stress-related receptors in the brain's cortex, but repeated exposures over 10 days showed the brain adapted to the radiation. The findings suggest that microwave radiation at levels similar to some wireless devices can trigger a stress response in the brain.

Effects of whole body microwave exposure on the rat brain contents of biogenic amines.

Inaba R, Shishido K, Okada A, Moroji T. · 1992

Researchers exposed rats to microwave radiation at 2450 MHz (the same frequency used in microwave ovens and WiFi) for one hour and measured changes in brain chemistry. They found that exposure altered the levels and processing of key brain chemicals called neurotransmitters, including noradrenaline and dopamine metabolites, which are crucial for mood, attention, and brain function. These neurochemical changes occurred even at the lower power level tested.

Brain & Nervous SystemNo Effects Found

Millimeter-wave effects on electric activity of crayfish stretch receptors.

Khramov RN, Sosunov EA, Koltun SV, Ilyasova EN, Lednev VV · 1991

Researchers exposed crayfish nerve cells to millimeter-wave radiation (similar to what 5G uses) at power levels up to 250 mW/cm2 and measured changes in nerve firing patterns. They found temporary decreases in nerve activity during exposure that returned to normal afterward, with the effects appearing to be caused by slight heating (about 1.5°C) rather than the electromagnetic fields themselves. This suggests that millimeter waves affect nerve function primarily through thermal heating rather than direct electromagnetic interference.

Japanese encephalitis virus (JEV): potentiation of lethality in mice by microwave radiation.

Lange DG, Sedmak J · 1991

Researchers exposed mice infected with Japanese encephalitis virus to microwave radiation at 2.45 GHz (the same frequency used in microwave ovens and WiFi). They found that microwave exposure made the viral infection significantly more deadly in a dose-dependent manner. The microwaves appeared to increase the permeability of blood vessels in the brain, allowing more virus to enter the central nervous system where it causes fatal damage.

Naltrexone pretreatment blocks microwave-induced changes in central cholinergic receptors.

Lai H, Carino MA, Wen YF, Horita A, Guy AW · 1991

Researchers exposed rats to microwave radiation at 2450 MHz (the same frequency as WiFi and microwave ovens) and found it altered brain receptors involved in memory and learning. When they gave the rats naltrexone (a drug that blocks opioid receptors) before exposure, it prevented these brain changes. This suggests microwave radiation affects the brain through the body's natural opioid system.

Immediate post-exposure effects of high-peak-power microwave pulses on operant behavior of Wistar rats.

Akyel Y, Hunt EL, Gambrill C, Vargas C Jr, · 1991

Researchers exposed rats to high-power microwave pulses and measured their ability to perform learned behaviors like pressing levers for food. At the highest exposure level (23 W/kg), the rats' body temperatures rose by 2.5°C and they completely stopped responding for 13 minutes, with performance remaining impaired afterward. The study concluded these behavioral disruptions were caused by the heating effects of the microwave radiation.

Physiological changes in rats after exposure to low levels of microwaves.

Ray S, Behari J · 1990

Researchers exposed rats to low-level microwave radiation (7.5 GHz) for 3 hours daily over 60 days and found significant physiological changes. The exposed animals ate and drank less, gained less weight, and showed altered blood parameters and organ weights compared to unexposed controls. The scientists concluded these changes represented a stress response triggered by microwave exposure affecting the central nervous system.

Microwave irradiation of rats at 2.45 GHz activates pinocytotic-like uptake of tracer by capillary endothelial cells of cerebral cortex.

Neubauer C, Phelan AM, Kues H, Lange DG · 1990

Researchers exposed rats to 2.45 GHz microwave radiation (WiFi frequency) at low power levels and found it increased blood-brain barrier permeability after just 30-120 minutes. This protective barrier normally prevents harmful substances from entering brain tissue, suggesting microwave exposure could compromise brain protection.

Microwave effects on acetylcholine-induced channels in cultured chick myotubes.

D’Inzeo, G et al · 1988

Italian researchers exposed muscle cells from chick embryos to low-power microwaves and measured how the cells responded to acetylcholine, a key neurotransmitter that controls muscle contraction. They found that microwave exposure reduced how often cellular channels opened in response to acetylcholine and made the cellular response fade faster. This suggests microwaves can interfere with normal nerve-to-muscle communication at the cellular level, even at low power levels.

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