Watilliaux A, Edeline JM, Lévêque P, Jay TM, Mallat M · 2011
Researchers exposed young rats on postnatal days 5, 15, or 35 to a GSM 1,800 MHz signal for 2 hours at 1.7–2.5 W/kg SAR and compared them to pseudo-exposed littermates. Western blotting measured heat shock proteins HSP60, HSC70, HSP90, serine racemase, glutamate transporters GLT1 and GLAST, and glial fibrillary acidic protein GFAP in total and soluble extracts. The GSM signal had no significant effect on any of these proteins, and immunohistochemical staining for CD68 showed no differences in microglial morphology or distribution.
Sakurai T et al. · 2011
The study used DNA microarray to examine gene expression in SVGp12 human glial cells after exposure to 2.45 GHz continuous-wave RF fields at SARs of 1, 5, and 10 W/kg for 1, 4, and 24 hours. Microarray analysis identified 23 assigned and 5 non-assigned gene spots as potentially altered. Follow-up RT-PCR analysis of Twenty-two genes showed no significant alterations in gene expression. The authors concluded that under their experimental conditions they found no evidence that RF field exposure affected gene expression in SVGp12 cells.
Yakymenko I, Sidorik E, Kyrylenko S, Chekhun V. · 2011
Mortazavi SMJ et al. · 2011
Eighty male rats were randomly divided into six groups of 13 to 15 animals. The first five groups received microwave exposure, microwave plus flaxseed oil, flaxseed continued after irradiation, flaxseed alone, or olive oil before a whole-body gamma-ray dose of 8 Gy on day 5. At 30 days, microwave-pretreated rats showed 100% survival, while control rats had 53.3% survival, and the other groups had survival fractions of 69.2%, 92.3%, 46.1%, and 61.5%.
Meo SA et al. · 2011
Forty male Wistar albino rats were divided into three groups: a control group of eight, a group exposed for 30 minutes/day, and a group exposed for 60 minutes/day for a total period of 3 months. Testicular morphological changes were examined under a light microscope. The 60-minute exposure group showed 18.75% hypospermatogenesis and 18.75% maturation arrest compared to controls, while the 30-minute group showed no abnormal findings.
Lukac N et al. · 2011
Researchers exposed bovine semen to 1800 MHz GSM-like RF-EMW in vitro and measured motility at 0, 30, 120, and 420 minutes using a computer-assisted semen analyzer. The percentage of motile and progressively motile sperm decreased significantly after 120 and 420 minutes of exposure. Average path distance decreased after 30 and 420 minutes, while path velocity initially increased at 30 minutes but decreased at 420 minutes. Amplitude of lateral head displacement also decreased significantly after 420 minutes.
Kumar NR, Sangwan S, Badotra P. · 2011
The study examined the effect of cell phone radiation on biomolecules in adult worker honey bees (Apis mellifera L). Exposed bees initially showed reduced motor activity and increased concentrations of proteins, carbohydrates, and lipids, then migrated en masse toward the phone. At later exposure stages, biomolecule concentrations declined slightly, and the researchers concluded that cell phone radiation influences honey bee behavior and physiology.
Jorge-Mora T et al. · 2011
Researchers investigated the effects of 2.45 GHz microwave radiation on the paraventricular nucleus of rat hypothalamus using c-Fos protein expression as a marker of cellular activation. Rats were exposed once or repeatedly (ten times in two weeks) to 2.45 GHz radiation at power intensities of 3 and 12 W in a GTEM cell, with SAR determined by Finite Difference Time Domain calculation. High SAR increased c-Fos expression at 90 minutes and 24 hours post-exposure, low SAR increased c-Fos counts at 24 hours, and repeated 3 W exposure increased PVN activation by more than 100% compared to acute exposure and non-radiated controls.
Ding S, Peng H, Fang HS, Zhou JL, Wang Z. · 2011
Seventy-two male adult Wistar rats were divided into three groups, with the PEMF group receiving LPS and methylprednisolone injections followed by 4 hours per day of PEMF stimulation for 1 to 8 weeks. The incidence of osteonecrosis was 29% in the PEMF group versus 75% in the methylprednisolone group, and no osteonecrosis occurred in the saline control group. Serum lipid levels were significantly lower in the PEMF and control groups than in the methylprednisolone group, and TGF-β1 mRNA and protein expression increased after PEMF treatment.
Costa FP et al. · 2011
A single-group, open-label, phase I/II study assessed the safety and effectiveness of intrabuccal amplitude-modulated electromagnetic fields at HCC-specific frequencies in 41 patients with advanced hepatocellular carcinoma and limited therapeutic options. Patients received three daily 60-minute outpatient treatments until disease progression or death. Treatment was well tolerated with no NCI grade 2, 3, or 4 toxicities. Fourteen patients (34.1%) had stable disease for more than 6 months, median progression-free survival was 4.4 months (95% CI 2.1–5.3), median overall survival was 6.7 months (95% CI 3.0–10.2), and there were three partial and one near complete responses.
Cammaerts MC, Debeir O, Cammaerts R. · 2011
Researchers examined Paramecium caudatum under normal conditions and near a switched-on GSM telephone operating at 900 MHz and 2 Watts. Exposed individuals moved more slowly and more sinuously than unexposed ones. Their physiology was affected: they became broader, their cytopharynx appeared broader, pulse vesicles had difficulty expelling content, cilia moved less efficiently, and trichocysts became more visible.
Maaroufi K et al. · 2011
Researchers examined the relationship between iron status, EMF exposure, and brain oxidative stress in young adult rats. They exposed rats to iron overload, 150 kHz EMF, or both, and measured lipid peroxidation and antioxidant enzyme activity in the prefrontal cortex, hippocampus, striatum, and cerebellum. Iron overload alone stimulated antioxidant defenses in the cerebellum and prefrontal cortex but did not cause oxidative stress. EMF exposure alone increased lipid peroxidation mainly in the cerebellum without affecting antioxidant defenses. Combined exposure further increased lipid peroxidation compared to EMF alone and abolished the antioxidant defense increase from iron overload alone.
Garaj-Vrhovac V et al. · 2011
The study examined workers occupationally exposed to pulsed microwave radiation from marine radars. Comet assay parameters (mean tail intensity 0.67 vs 1.22, moment 0.08 vs 0.16) and micronucleus test parameters showed statistically significant differences between exposed and unexposed groups. Glutathione concentration was significantly lower in exposed workers (1.24 vs 0.53) while malondialdehyde concentration was significantly higher (1.74 vs 3.17), indicating oxidative stress. Electromagnetic field strength was measured at marine radar frequencies of 3 GHz, 5.5 GHz, and 9.4 GHz with specific absorption rate values determined.
Hajnorouzi A et al. · 2011
The researchers hypothesized that an appropriate combination of a geomagnetic field as a static field and an alternative magnetic field may promote maize seedling growth by alleviating excess reactive oxygen species production. The seeds were germinated in the magnetic field for 4 days and then allowed to grow in a nutrient solution for another 4 days. Magnetic field-treated seedlings grew faster, had lower superoxide dismutase activity, and higher total antioxidant capacity than controls. The maintenance of membrane integrity and a decrease of iron content in treated seedlings suggest that the combined static and alternative magnetic fields promote growth by lowering iron absorption, reducing Fenton chemistry, and lowering oxidative burst risk.
Saygin M, Caliskan S, Karahan N, Koyu A, Gumral N, Uguz A · 2011
Researchers used twelve-week-old male Wistar Albino rats divided into cage control, sham control, and 2.45 GHz EMR groups, with the exposure group receiving 3.21 W/kg for 60 minutes daily over 28 days. The exposed rats showed a significant reduction in Leydig cell numbers compared to cage controls. Spermatogenesis scores differed significantly between groups, and Bax gene and Caspase-8 enzyme levels showed significant changes.
Sannino A et al. · 2011
Researchers exposed human peripheral blood lymphocytes in G0, G1, or S-phase to 900 MHz RF at 1.25 W/kg for 20 hours, then treated them with mitomycin C. The incidence of micronuclei was evaluated to determine adaptive response. Cells exposed in S-phase showed an adaptive response, while those exposed in G0 or G1 did not.
Poulletier de Gannes F et al. · 2011
Researchers exposed three human brain cell lines and primary cortical neurons to the EDGE signal at 1800 MHz. Four exposure conditions were tested: 2 and 10 W/kg for 1 and 24 hours. Reactive oxygen species production was measured by flow cytometry using the DCFH-DA probe. All cells tested responded to rotenone treatment by increasing ROS production. The EDGE signal did not induce oxidative stress under any test condition, including at 10 W/kg.
Lee JW, Kim MS, Kim YJ, Choi YJ, Lee Y, Chung HW. · 2011
Researchers investigated the genotoxic potential of 3 T clinical MRI scans in cultured human lymphocytes by exposing them to electromagnetic fields from a clinical brain protocol for 22, 45, 67, and 89 minutes. They observed a significant increase in single-strand DNA breaks after exposure. Micronuclei and chromosome aberration frequencies increased in a time-dependent manner.
Kumar S, Kesari KK, Behari J. · 2011
Esmekaya MA et al. · 2011
Researchers investigated the mutagenic and morphologic effects of 1.8GHz GSM radiofrequency radiation, alone and combined with Ginkgo biloba (EGb 761) pre-treatment, in human peripheral blood lymphocytes using Sister Chromatid Exchange and electron microscopy. There was a significant increase (p<0.05) in Sister Chromatid Exchange frequency in RF-exposed lymphocytes compared to sham controls. RF radiation also inhibited cell viability in a time-dependent manner, and EGb 761 pre-treatment significantly increased cell viability at 8 and 24 hours compared to RF-exposed groups alone.
Aly H., Ashraf & deris, Safaai & Zaki, Nazar. (2011). · 2011
Researchers investigated whether radiofrequency field exposure could affect the activity of human immune system cells by studying the activity and behavior of human leukocytes upon exposure to radiofrequency fields. Human blood leukocytes were exposed to 1800 MHz RF radiation (SAR of 1.25 W/Kg, Power density of 0.1 mW/cm2) from a mobile phone when placed within a distance of 5 cm from the microscope stage. The maximum speed exceeded that measured at any temperature by approximately 50%, and a significant change was observed in leukocyte movement direction and cell behavior, including shrinking, expanding, and rolling.
Falzone N, Huyser C, Becker P, Leszczynski D, Franken DR. · 2011
Highly motile human spermatozoa were exposed for 1 hour to 900-MHz mobile phone radiation at a specific absorption rate of 2.0 W/kg and examined at various times after exposure. The radiation did not affect the sperm acrosome reaction, but significant reductions were found in sperm head area and acrosome percentage of the head area among exposed sperm compared with unexposed controls. The mean number of zona-bound sperm was 22.8 in exposed samples versus 31.8 in controls, a statistically significant difference (p < 0.05). The researchers concluded that these results could indicate a significant effect of RF-EMF on sperm fertilization potential.
Cao Y, Xu Q, Jin ZD, Zhou Z, Nie JH, Tong J. · 2011
Adult male Kunming mice were exposed to 900 MHz radiofrequency fields at power intensities of 12, 120 and 1200 μW/cm(2) for 1 h/day for 14 days and then subjected to whole body gamma-irradiation. Compared with mice exposed to gamma-radiation alone, the RF pre-exposed mice showed a significant increase in survival time and a reduction in hematopoietic tissue damage. The researchers described this effect as appearing similar to the 'adaptive response' which is well documented in scientific literature.
Aydin B, Akar A. · 2011
Researchers exposed immature and mature rats to a 900-MHz electromagnetic field for 2 hours per day for 45 days and measured oxidative stress in lymphoid organs, polymorphonuclear leukocytes, and plasma. Antioxidant enzyme activity, glutathione levels in lymphoid organs, and the antioxidant capacity of plasma decreased after exposure, while lipid peroxidation, nitric oxide levels, and myeloperoxidase activity increased. Improvements seen after a recovery period were limited, especially in immature rats, and oxidative damage was described as tissue specific.
Savić T, Janać B, Todorović D, Prolić Z. · 2011
Researchers investigated how a static magnetic field affected development and viability in Drosophila melanogaster and Drosophila hydei. Eggs of both species were exposed to an average magnetic induction of 60 mT throughout full development from egg to adult. Exposure reduced development time in both species, though statistical significance was found only for D. hydei, and viability was significantly weaker in both exposed species compared to controls.
