3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 1,453 studies in Cellular Effects

Effects of Global System for Mobile Communications 1800 MHz radiofrequency electromagnetic fields on gene and protein expression in MCF-7 cells.

Zeng Q, Chen G, Weng Y, Wang L, Chiang H, Lu D, Xu Z. · 2006

Researchers exposed human breast cancer cells (MCF-7) to cell phone radiation at 1800 MHz for 24 hours to see if it changed gene and protein activity. While initial tests suggested some genes might be affected, follow-up verification tests found no consistent changes. The study concluded that cell phone radiation at these levels does not produce convincing evidence of biological effects on cellular gene or protein expression.

[Effects of GSM 1800 MHz radiofrequency electromagnetic fields on protein expression profile of human breast cancer cell MCF-7.]

Zeng QL, Weng Y, Chen GD, Lu DQ, Chiang H, Xu ZP · 2006

Researchers exposed human breast cancer cells to cell phone radiation at levels similar to what phones produce, testing different exposure patterns and durations. They found that the radiation changed how cells produced proteins, particularly affecting proteins involved in DNA repair, cell communication, and basic cellular functions. The changes depended on both how long the cells were exposed and whether the exposure was continuous or intermittent.

Chronic exposure to GSM 1800-MHz microwaves reduces excitatory synaptic activity in cultured hippocampal neurons.

Xu S, Ning W, Xu Z, Zhou S, Chiang H, Luo J. · 2006

Researchers exposed rat brain cells to 1800-MHz cell phone radiation (the same frequency used by GSM phones) for 15 minutes daily over 8 days. They found that this exposure weakened the electrical connections between brain cells in the hippocampus, the brain region crucial for memory and learning. The radiation reduced the strength of signals that brain cells use to communicate with each other.

Effects of a 2450 MHz high-frequency electromagnetic field with a wide range of SARs on the induction of heat-shock proteins in A172 cells.

Wang J et al. · 2006

Researchers exposed human brain cells (A172) to microwave radiation at 2450 MHz (the same frequency used in microwave ovens and WiFi) to see if it triggers cellular stress responses. They found that extremely high radiation levels (100-200 W/kg) caused specific stress protein changes that couldn't be explained by heating alone. This suggests microwave radiation may cause biological stress in cells through mechanisms beyond just warming tissue.

HSP27 phosphorylation increases after 45 degrees C or 41 degrees C heat shocks but not after non-thermal TDMA or GSM exposures.

Vanderwaal RP, Cha B, Moros EG, Roti Roti JL. · 2006

Scientists tested whether cell phone radiation triggers the same cellular stress response as heat in laboratory cells. While heat clearly activated stress proteins, cell phone signals at levels 5-10 times higher than normal phone use caused no detectable stress response, suggesting different biological effects.

Immunotropic influence of 900 MHz microwave GSM signal on human blood immune cells activated in vitro.

Stankiewicz W et al. · 2006

Polish researchers exposed human immune cells to 900 MHz GSM cell phone signals at very low power levels (SAR 0.024 W/kg) and found that the microwave exposure significantly increased immune cell activity. The exposed cells showed stronger responses to immune stimulants and higher activity levels compared to unexposed control cells. This suggests that even low-level cell phone radiation can alter how your immune system functions at the cellular level.

Protein Kinase C Activity in developing rat brain cells exposed to 2.45 GHz radiation

Paulraj R, Behari J · 2006

Researchers exposed developing rat brains to 2.45 GHz radiation (the same frequency as WiFi and microwaves) for 2 hours daily over 35 days. They found significant decreases in protein kinase C activity in the hippocampus, a brain region crucial for learning and memory, plus increased glial cells which can indicate brain inflammation. The study suggests that chronic microwave exposure during brain development may interfere with normal growth and cellular function.

Single strand DNA breaks in rat brain cells exposed to microwave radiation.

Paulraj R, Behari J · 2006

Researchers exposed developing rat brains to microwave radiation at frequencies commonly used in WiFi and radar systems (2.45 and 16.5 GHz) for 35 days. They found statistically significant DNA damage in brain cells, specifically single-strand breaks that can interfere with normal cellular function. This suggests that chronic exposure to low-level microwave radiation during brain development may cause genetic damage.

Mobile phone radiation causes changes in gene and protein expression in human endothelial cell lines and the response seems to be genome- and proteome-dependent.

Nylund R, Leszczynski D · 2006

Finnish researchers exposed human blood vessel cells to mobile phone radiation for one hour and found that genes and proteins changed differently in each cell type. This suggests that cellular response to phone radiation depends on the specific genetic makeup of cells, potentially explaining conflicting research results.

Immunotropic influence of 900 MHz microwave GSM signal on human blood immune cells activated in vitro.

Stankiewicz W et al. · 2006

Researchers exposed human immune cells to 900 MHz microwave radiation (similar to GSM cell phone signals) at very low power levels and found that the radiation significantly increased immune cell activity. The exposed cells showed stronger responses to immune stimulants compared to unexposed control cells. This suggests that even weak microwave radiation can alter how our immune system functions.

Modest increase in temperature affects ODC activity in L929 cells: low-level radiofrequency radiation does not.

Hoyto A, Sihvonen AP, Alhonen L, Juutilainen J, Naarala J · 2006

Researchers exposed mouse cells to cell phone-level radiofrequency radiation for 24 hours. The RF radiation itself caused no biological effects, but tiny temperature increases (less than 1°C) significantly affected cellular enzyme activity, showing temperature control is crucial in EMF studies.

Reproductive Health100 citations

Effect of whole-body 1800MHz GSM-like microwave exposure on testicular steroidogenesis and histology in mice.

Forgacs Z et al. · 2006

Hungarian researchers exposed male mice to cell phone-like radiation (1800 MHz GSM) for 48 hours at very low power levels (0.018-0.023 W/kg). They found that exposed mice had significantly higher testosterone levels in their blood and increased red blood cell counts, though no visible damage to reproductive organs. The study suggests that even brief, low-level microwave exposure can trigger measurable hormonal changes in male reproductive systems.

Exposure to AC and DC magnetic fields induces changes in 5-HT1B receptor binding parameters in rat brain membranes.

Espinosa JM, Liberti M, Lagroye I, Veyret B. · 2006

Scientists exposed rat brain tissue to magnetic fields from power lines and found significant changes in serotonin receptors that control mood and sleep. One hour of exposure at levels found near electrical equipment altered brain chemistry, demonstrating that common magnetic field exposure can directly affect how brain cells function.

Exposure of rat brain to 915 MHz GSM microwaves induces changes in gene expression but not double stranded DNA breaks or effects on chromatin conformation.

Belyaev IY et al. · 2006

Scientists exposed rats to cell phone radiation at 915 MHz for 2 hours and found it changed gene activity in the brain without causing DNA breaks. The radiation altered the expression of 12 genes involved in brain functions like neurotransmitter regulation, the blood-brain barrier, and melatonin production. This suggests that even brief cell phone exposure can trigger biological changes in brain cells, even when DNA damage isn't detectable.

Effects of GSM 1800 MHz radiofrequency electromagnetic fields on DNA damage in Chinese hamster lung cells.

Zhang DY, Xu ZP, Chiang H, Lu DQ, Zeng QL. · 2006

Chinese researchers exposed hamster lung cells to cell phone radiation at 1800 MHz (the frequency used by GSM networks) for either 1 or 24 hours to see if it would damage DNA. They found that 24-hour exposure at high intensity (3.0 W/kg) significantly increased DNA damage markers compared to unexposed cells, while 1-hour exposure showed no effect. This suggests that prolonged exposure to cell phone-type radiation may harm cellular DNA.

DNA damage and repair induced by acute exposure of microwave from mobile phone on cultured human lens epithelial cells

Sun LX, Yao K, Jiang H, He JL, Lu DQ, Wang KJ, Li HW · 2006

Researchers exposed human eye lens cells to cell phone radiation at different power levels for 2 hours to see if it damaged DNA. They found that lower exposure levels (similar to typical phone use) caused no DNA damage, but higher levels (4 times normal) did cause measurable DNA breaks and reduced cell growth. This suggests there may be a threshold below which cells can repair radiation damage effectively.

[Effect of acute exposure to microwave from mobile phone on DNA damage and repair of cultured human lens epithelial cells in vitro.]

Sun LX, Yao K, He JL, Lu DQ, Wang KJ, Li HW. · 2006

Researchers exposed human eye lens cells to cell phone radiation for 2 hours at different power levels to see if it damages DNA. They found that lower exposure levels (up to 3 W/kg) caused temporary DNA breaks that the cells could repair, but higher exposure (4 W/kg) caused permanent DNA damage that cells couldn't fix.

Oxidative Stress104 citations

GSM Base Station Electromagnetic Radiation and Oxidative Stress in Rats.

Yurekli AI et al. · 2006

Turkish researchers exposed rats to cell tower radiation at 945 MHz for an unspecified duration and measured markers of oxidative stress (cellular damage from free radicals). They found that exposure at power levels well below current safety limits significantly increased harmful oxidative markers and decreased protective antioxidants in the rats. This suggests that even low-level electromagnetic radiation from cell towers may trigger cellular stress responses.

Oxidative Stress147 citations

Protective effects of melatonin and caffeic acid phenethyl ester against retinal oxidative stress in long-term use of mobile phone: A comparative study.

Ozguner F, Bardak Y, Comlekci S. · 2006

Researchers exposed rats to cell phone radiation (900 MHz) for 30 minutes daily over 60 days. The radiation caused significant oxidative damage to retinal tissue in the eyes. Two natural antioxidants, melatonin and CAPE, successfully protected against this damage, suggesting potential eye health risks from prolonged phone use.

Modulation of MCP-1 and iNOS by 50-Hz sinusoidal electromagnetic field

Reale M et al. · 2006

Researchers exposed human immune cells called monocytes to 50 Hz magnetic fields (the same frequency as power lines) at 1 milliTesla overnight. They found the fields altered production of two important immune signaling molecules: reducing nitric oxide synthase (which helps fight infections) while increasing MCP-1 (which attracts immune cells to sites of inflammation). These changes suggest power-frequency magnetic fields can disrupt normal immune system function.

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