6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 6,486 peer-reviewed studies on electromagnetic field health effects from 4 research libraries.

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Showing 706 studies in DNA & Genetic Damage

DNA & Genetic DamageNo Effects Found

Absence of a synergistic effect between moderate-power radio-frequency electromagnetic radiation and adriamycin on cell-cycle progression and sister-chromatid exchange.

Ciaravino V, Meltz ML, Erwin DN · 1991

Researchers exposed Chinese hamster ovary cells to adriamycin and pulsed RFR at 2,450 MHz and 33.8 W/Kg for 2 h. The maximal temperature in the tissue-culture medium was 39.7 +/- 0.2 degrees C. The experiments were controlled for chemical and RFR exposures as well as for temperature. Verified statistically, the data indicate that the RFR did not affect changes in cell progression caused by adriamycin and did not change the number of sister chromatid exchanges induced by adriamycin.

Marked increase in the teratogenicity of the combined administration of the industrial solvent 2-methoxyethanol and radiofrequency radiation in rats.

Nelson BK et al. · 1991

The exploratory study aimed to determine whether concurrent exposure to RF radiation and 2-methoxyethanol enhances developmental toxicity in rats. In the primary study, pregnant rats were exposed to RF radiation sufficient to raise rectal temperature to 42.0°C for 30 minutes and given 150 mg/kg 2-methoxyethanol by gavage, and the combination raised mean fetal malformations per litter to 76% from 14% with 2ME alone and 30% with RF alone. The severity of malformations also increased with the combination, scoring 6 on a relative severity scale compared with less than 1 for 2ME alone and 3 for RF alone.

[The participation of thyroid hormones in modifying the mutagenic effect of microwaves].

Koveshnikova IV, Antipenko EN · 1991

Researchers studied whether thyroid hormones play a role in modifying the mutagenic effect of microwaves in rats. The mutagenic effect of microwaves at 2,450 or 2,750 MHz, 500 microW/cm2, for 30 days at 7 hours a day increased when rats had either low or high thyroid hormone levels. The researchers concluded that normal thyroid gland functioning appears to be an important condition for maintaining chromosome integrity under microwave exposure.

DNA & Genetic DamageNo Effects Found

Proflavin and microwave radiation: absence of a mutagenic interaction.

Meltz ML, Eagan P, Erwin DN · 1990

Researchers studied forward mutation at the thymidine kinase locus in L5178Y mouse leukemic cells exposed to 2.45-GHz pulsed-wave RFR and proflavin. Exposures used 500 or 600 W net forward power, giving a SAR of approximately 40 W/kg, for 4 hours with temperature controls. No statistically significant increase in mutant frequency was found with combined RFR and proflavin versus proflavin alone, no change in colony-size distribution occurred, and RFR alone showed no mutagenic action.

The effect of microwave radiation on the cell genome

Garaj-Vrhovac V, Horvat D, Koren Z · 1990

Researchers exposed cultured V79 Chinese hamster cells to continuous microwave radiation at 7.7 GHz and a power density of 30 mW/cm2 for 15, 30, and 60 minutes. The study measured the incorporation of [3H]thymidine into DNA and the frequency of chromosome aberrations. Inhibition of [3H]thymidine incorporation occurred through complete prevention of DNA from entering into the S phase, and the normal rate of incorporation recovered within one generation cycle of V79 cells. Compared with control samples, irradiated cells showed a higher frequency of specific chromosome lesions.

DNA & Genetic DamageNo Effects Found

Effect of radiofrequency radiation on mRNA expression in cultured rodent cells.

Parker JE, Kiel JL, Winters WD · 1988

Researchers exposed four rodent cell lines to 2450 MHz microwave radiation at a Specific Absorption Rate of 103.5 +/- 4.2 W/kg at temperatures of 37, 40, 42, and 45 degrees C. The researchers extracted mRNA from exposed and sham-exposed cells and used DNA probes of oncogenes, heat shock protein, or long terminal repeat sequences to look for differences in mRNA expression. With the cell lines and probes used, no significant differences in mRNA expression were observed after microwave exposure.

Transcriptional Patterns in the X Chromosome of Sciara coprophila Following Exposure to Magnetic Fields

Reba Goodman, Joan Abbott, Ann S. Henderson · 1987

Researchers exposed salivary gland cells from Sciara coprophila larvae to three magnetic field signals: a 72-Hz single repetitive pulse, a 15-Hz repetitive pulse burst, and a 72-Hz sine wave. Eight normally active X chromosome regions showed increased transcription, and three regions (Xc, B", Xf) became detectably active only after exposure. The sine wave and single pulse signals produced stronger transcriptional responses than the pulse train signal.

Microwave effects on plasmid DNA

Unknown authors · 1987

Purified plasmid DNA was exposed to microwave radiation at nonthermal levels in the frequency range from 2.00 to 8.75 GHz. The exposure produced single- and double-strand breaks detected by agarose gel electrophoresis. Microwave-induced DNA damage depended on the presence of small amounts of copper. The effect was dependent on both microwave power and exposure duration. Cuprous ions, but not cupric ions, mimicked the microwave effects on DNA.

THE DETECTION OF RF DAMAGE TO HIGH MOLECULAR WEIGHT BIOPOLYMERS BY RAMAN SPECTROSCOPY

Charles A. Cody et al. · 1975

Researchers used a custom Raman spectrometer assembled by Block Engineering personnel to obtain Raman spectra. Infrared spectra were recorded on a Digilab FTS-15 Fourier transform spectrophotometer. The program established that biological materials do damage when exposed to RF radiation and that molecular spectroscopy methods yield data needed to generate RF radiation hazard parameters. Raman spectroscopy encountered fluorescence and sensitivity problems, while infrared techniques appeared satisfactory from preliminary data but the effect of water-rich background matrices and the ability to do micro-damage assessment were not completely known.

Use of radiation-sensitive bacterial mutants in the detection of deleterious effects of environmental agents

Mattern IE, Roberti B · 1974

Researchers used radiation-sensitive mutants of Uscherichin coli and Salmonella tuphimurcun in the study. The mutants were employed to identify environmental pollutants that damaze DN. Liver homogenates were added to the test system to imitate in vivo metabolism. The study also investigated the effects of 3 iHl% microwaves on hrologic Vival and mutation taduction.

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