3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 481 studies in DNA & Genetic Damage

DNA & Genetic DamageNo Effects Found

Assessment of nuclear abnormalities in exfoliated cells from the oral epithelium of mobile phone users

Souza LD, Cerqueira ED, Meireles JR · 2014

Brazilian researchers examined cells from the mouths of 45 mobile phone users to look for DNA damage and cell death markers. They found no differences in most cellular damage markers between light, moderate, and heavy phone users (more than 5 hours per week). However, heavy users showed significantly more 'broken egg' structures in their cells, which may indicate gene amplification problems.

DNA & Genetic DamageNo Effects Found

Effect of 950 MHz UHF electromagnetic radiation on biomarkers of oxidative damage, metabolism of UFA and antioxidants in the livers of young rats of different ages

Furtado-Filho OV et al. · 2014

Brazilian researchers exposed young rats to cell phone-level radiation (950 MHz) for 30 minutes daily, starting before birth and continuing up to 30 days after birth. They found no evidence of oxidative stress or DNA damage in most age groups, though 30-day-old rats showed some genetic changes and newborns had altered fatty acid levels in their livers. The study suggests that developing animals may be more resilient to short-term RF radiation exposure than previously thought.

DNA & Genetic DamageNo Effects Found

Increased γ-H2AX by exposure to a 60-Hz magnetic fields combined with ionizing radiation, but not hydrogen peroxide, in non-tumorigenic human cell lines.

Yoon HE, Lee JS, Myung SH, Lee YS · 2014

Researchers exposed human lung cells to 60-Hz magnetic fields at different strengths and measured DNA damage markers. They found that stronger magnetic fields (2 mT) caused DNA damage on their own and made cells more vulnerable to radiation damage, while weaker fields (1 mT) had no effect. This suggests that power-frequency magnetic fields can damage DNA at high enough levels.

DNA & Genetic DamageNo Effects Found

Absence of DNA damage after 60-Hz electromagnetic field exposure combined with ionizing radiation, hydrogen peroxide, or c-Myc overexpression.

Jin YB et al. · 2014

Researchers exposed four different types of human and mouse cells to 60 Hz magnetic fields (the same frequency as power lines) for 4 to 16 hours, both alone and combined with known DNA-damaging agents like radiation and hydrogen peroxide. They found no DNA damage from the magnetic field exposure alone, and the magnetic fields did not make other DNA-damaging agents more harmful. This suggests that power-frequency magnetic fields at 1 milliTesla may not directly damage cellular DNA.

DNA & Genetic DamageNo Effects Found

Effect of long-term 50 Hz magnetic field exposure on the micronucleated polychromatic erythrocytes of mice.

Alcaraz M, Olmos E, Alcaraz-Saura M, Achel DG, Castillo J. · 2014

Researchers exposed mice to 50 Hz magnetic fields (the same frequency as power lines) for up to 28 days and found evidence of genetic damage in bone marrow cells. The magnetic field exposure caused an increase in micronucleated cells, which are markers of DNA damage, though the effect was less than X-ray radiation. Importantly, antioxidants that protect against radiation damage did not protect against the magnetic field damage, suggesting different biological mechanisms.

The influence of direct mobile phone radiation on sperm quality.

Gorpinchenko I, Nikitin O, Banyra O, Shulyak A. · 2014

Researchers exposed healthy men's sperm samples to mobile phone radiation for 5 hours and compared them to unexposed samples. The exposed sperm showed significantly reduced swimming ability and increased DNA damage (fragmentation of genetic material). This suggests that cell phone radiation can directly harm sperm quality, which could impact male fertility.

Connection between Cell Phone use, p53 Gene Expression in Different Zones of Glioblastoma Multiforme and Survival Prognoses.

Akhavan-Sigari R, Baf MM, Ariabod V, Rohde V, Rahighi S. · 2014

Researchers studied brain tumor tissue from 63 patients with glioblastoma multiforme (the most aggressive type of brain cancer) to see if cell phone use affected gene expression. They found that patients who used cell phones for 3 or more hours daily had significantly higher levels of mutated p53 genes in their tumors - a marker associated with cancer progression and shorter survival times. This suggests heavy cell phone use may influence how aggressive these brain cancers become at the genetic level.

Epigenetic Modulation of Adult Hippocampal Neurogenesis by Extremely Low-Frequency Electromagnetic Fields.

Leone L et al. · 2014

Researchers exposed neural stem cells from mouse brains to extremely low-frequency electromagnetic fields (ELF-EMF) and found these fields enhanced the growth of new brain cells in the hippocampus, the brain region crucial for memory formation. The ELF-EMF exposure triggered specific genetic changes that promoted brain cell development and improved spatial learning and memory in the mice. This suggests that certain electromagnetic field exposures might actually stimulate beneficial brain processes rather than harm them.

Effect of electromagnetic irradiation produced by 3G mobile phone on male rat reproductive system in a simulated scenario.

Kumar S, Nirala JP, Behari J, Paulraj R. · 2014

Researchers exposed male rats to electromagnetic radiation from 3G mobile phones to study effects on reproductive health. They found significant damage including reduced sperm count, DNA damage in sperm cells, and decreased testicular weight. The findings suggest that mobile phone radiation may harm male fertility.

Metabolic and genetic screening of electromagnetic hypersensitive subjects as a feasible tool for diagnostics and intervention.

De Luca C et al. · 2014

Italian researchers analyzed blood samples from 153 people with electromagnetic hypersensitivity (EHS) and found distinctive metabolic changes including increased oxidative stress and specific genetic variations. These blood markers could potentially serve as diagnostic tools to identify EHS as a legitimate medical condition.

Effect of 3G cell phone exposure with computer controlled 2-D stepper motor on non-thermal activation of the hsp27/p38MAPK stress pathway in rat brain.

Kesari KK, Meena R, Nirala J, Kumar J, Verma HN. · 2014

Researchers exposed young rats to 3G cell phone radiation for 2 hours daily over 60 days and examined their brain tissue. The study found significant DNA damage, increased cell death, and activation of stress response pathways in the brain. These findings suggest that prolonged cell phone exposure may harm brain cells through oxidative stress and cellular damage mechanisms.

RKIP Regulates Neural Cell Apoptosis Induced by Exposure to Microwave Radiation Partly Through the MEK/ERK/CREB Pathway.

Zuo H et al. · 2014

Researchers exposed neural cells to microwave radiation at 2.856 GHz for 5 minutes and found that the radiation triggered cell death (apoptosis) by disrupting a key protective protein called RKIP. When RKIP levels dropped after radiation exposure, it activated harmful cellular pathways that led to DNA fragmentation and neural cell death. This study identifies a specific biological mechanism by which microwave radiation can damage brain cells.

Adaptive response in human blood lymphocytes exposed to non-ionizing radiofrequency fields: resistance to ionizing radiation-induced damage

Sannino A et al. · 2014

Researchers exposed human blood cells to radiofrequency radiation (similar to cell phone signals) for 20 hours, then subjected them to X-ray radiation. Surprisingly, the cells that received the RF pre-exposure showed significantly less genetic damage from the X-rays compared to cells that only received X-rays. This suggests that low-level RF exposure may trigger protective mechanisms that help cells resist subsequent DNA damage.

Mobile Phone Radiation Alters Proliferation of Hepatocarcinoma Cells.

Ozgur E, Guler G, Kismali G, Seyhan N · 2014

Researchers exposed liver cancer cells to mobile phone radiation at levels typical of phone use (2 W/kg SAR) for up to 4 hours. The radiation decreased cell survival and caused DNA damage, with 1,800-MHz frequencies proving more harmful than 900-MHz. This suggests that the radiofrequency radiation from mobile phones can directly damage cells at exposure levels considered safe by current regulations.

Therapeutic approaches of melatonin in microwave radiations-induced oxidative stress-mediated toxicity on male fertility pattern of Wistar rats

Meena R, Kumari K, Kumar J, Rajamani P, Verma HN, Kesari KK · 2014

Researchers exposed male rats to WiFi-frequency radiation (2.45 GHz) for 2 hours daily over 45 days, finding significant damage to sperm production and testosterone levels. Melatonin supplements prevented most reproductive harm, suggesting microwave radiation threatens male fertility but antioxidants may offer protection.

Long term and excessive use of 900 MHz radiofrequency radiation alter microrna expression in brain.

Dasdag S et al. · 2014

Turkish researchers exposed rats to cell phone radiation (900 MHz) for 3 hours daily over an entire year and found it altered microRNA in brain tissue. MicroRNAs are tiny molecules that control gene activity and play crucial roles in brain function, cell growth, and death. This study demonstrates that chronic radiofrequency exposure can disrupt these fundamental cellular control mechanisms in the brain.

Adaptive Response in Mice Exposed to 900 MHz Radiofrequency Fields: Bleomycin-induced DNA and Oxidative Damage/Repair.

Zong C, Ji Y, He Q, Zhu S, Qin F, Tong J, Cao Y. · 2014

Researchers exposed mice to cell phone frequency radiation (900 MHz) for 4 hours daily for a week, then injected them with a DNA-damaging drug called bleomycin. They found that mice pre-exposed to the radiation showed less DNA damage from the drug and better antioxidant defenses compared to mice that received only the drug. This suggests the radiation exposure triggered protective cellular responses that helped the mice resist subsequent damage.

Therapeutic approaches of melatonin in microwave radiations-induced oxidative stress-mediated toxicity on male fertility pattern of Wistar rats

Meena R, Kumari K, Kumar J, Rajamani P, Verma HN, Kesari KK. · 2014

Researchers exposed male rats to Wi-Fi frequency radiation (2.45 GHz) for 2 hours daily over 45 days, finding it damaged sperm DNA and caused oxidative stress in testicular tissue. The antioxidant melatonin prevented this damage, suggesting everyday microwave radiation may harm male fertility but antioxidants could provide protection.

Increased DNA oxidation (8-OHdG) and protein oxidation (AOPP) by low level electromagnetic field (2.45 GHz) in rat brain and protective effect of garlic.

Hatice Ş. Gürler et al. · 2014

Researchers exposed rats to WiFi-frequency radiation (2.45 GHz) for one hour daily over 30 days and measured damage to DNA and proteins in their brains. The radiation caused significant DNA damage in both brain tissue and blood, while also increasing harmful protein changes in the blood. Interestingly, rats given garlic supplements showed protection against these damaging effects.

Increased DNA oxidation (8-OHdG) and protein oxidation (AOPP) by Low level electromagnetic field (2.45 GHz) in rat brain and protective effect of garlic.

Gürler HS, Bilgici B, Akar AK, Tomak L, Bedir A. · 2014

Researchers exposed rats to WiFi-frequency radiation (2.45 GHz) for one hour daily over 30 days and measured DNA damage in their brains and blood. The radiation caused significant genetic damage, indicated by increased levels of 8-OHdG (a marker of DNA oxidation) in both brain tissue and blood plasma. Interestingly, rats given garlic extract were protected from this DNA damage, suggesting antioxidants may help counter EMF-induced cellular harm.

Magnetic field-induced oxidative stress and DNA damage in Mediterranean flour moth Ephestia kuehniella Zeller (Lepidoptera: Pyralidae) larvae

Pandir D, Sahingoz R · 2014

Researchers exposed Mediterranean flour moth larvae to extremely strong magnetic fields (1.4 Tesla at 50 Hz) for periods ranging from 3 to 72 hours and found significant DNA damage and oxidative stress. The longer the exposure, the more severe the genetic damage and cellular stress became, as measured by multiple biochemical markers. This study demonstrates that magnetic field exposure can cause measurable biological harm at the cellular level.

Induction of genomic instability, oxidative processes, and mitochondrial activity by 50Hz magnetic fields in human SH-SY5Y neuroblastoma cells.

Luukkonen J, Liimatainen A, Juutilainen J, Naarala J · 2014

Finnish researchers exposed human brain cells to 50Hz magnetic fields from power lines for 24 hours. The exposure caused lasting genetic damage and cellular stress that persisted for up to 15 days, suggesting common household magnetic fields can trigger long-term harmful effects in cells.

An evaluation of genotoxicity in human neuronal-type cells subjected to oxidative stress under an extremely low frequency pulsed magnetic field.

Giorgi G et al. · 2014

Italian researchers exposed human brain cells to power line frequency magnetic fields (50 Hz) while simultaneously stressing them with hydrogen peroxide. Over 72 hours, the magnetic field exposure did not increase DNA damage beyond what the chemical stress alone caused, suggesting power-frequency fields may not worsen cellular damage.

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