Charles L. Sheridan et al. · 1979
The longevity study of mice exposed in utero to near-lethal 2450-MHz microwave radiation is in its third year with mortality rising in both groups. Spontaneous tumors appeared in two control mice (n=81) but not in radiated mice (n=83), a difference too narrow to exclude chance. Acute studies in anesthetized rats, guinea pigs, and rabbits showed that brief near-lethal 2450-MHz exposures produced whole-body temperature rises of 4.5 to 12 K and altered thermal distributions, with the brain stem appearing thermally privileged. Twelve pilot studies were completed to optimize microwave hyperthermia as adjuvant treatment for experimentally induced glioblastoma in rats.
John R. Thomas, Linda S. Burch · 1979
Four male Long-Evans rats were trained on a fixed-interval schedule requiring a lever press for food pellets. The rats were exposed to 2.45 GHz pulsed microwave radiation at an average power density of 1 mW/cm² for 30 minutes before behavioral sessions. Chlordiazepoxide alone increased response rates up to a maximum, but combined with microwave radiation the drug's effects were potentiated. Behavior returned to baseline after each session.
S.M. Bawin, I. Sabbot, B. Bystrom, P.M. Sagan, W.R. Adey · 1979
Researchers exposed groups of 30 male albino rats to vertical 60 Hz electric fields at 0, 50, 500, and 1000 V/m for 30 days. Throughout the 44-day experiment they measured body weight, water and food consumption, urine output, and general activity.
Robert P. Liburdy · 1979
Researchers exposed mice to whole-body radiofrequency radiation at 26 MHz that raised core temperature by 2°C over 15 minutes, inducing transient lymphopenia and increasing splenic T- and B-lymphocytes. Repeated RFR exposures sustained lymphopenia and further elevated splenic T- and B-lymphocyte levels. Chronic RFR exposure decreased thymic weight, thymic and splenic cell density, and suppressed delayed-type hypersensitivity. Warm air exposure increased only splenic B-lymphocytes and did not change delayed hypersensitivity, while RFR exposure raised plasma corticoid levels severalfold. A synthetic glucocorticoid reproduced the lymphopenia, splenic T- and B-lymphocyte increases, and thymic involution observed with RFR.
Jana Pazderová-Vejlupková, Marcel Josífko · 1979
Alkaline phosphatase activity in neutrophils rose significantly in the first week of irradiation and fell transiently after irradiation ceased. In the post-irradiation interval, exposed rats displayed a significant decline in rate of body weight increase.
Ohno, K., Pettigrew, K.D., Rapoport, S.I. · 1978
They measured cerebrovascular permeability-area products for 14C-sucrose in 5 brain regions. Mean PA values were similar across sham, 1 mW /cm², and 10 mW/cm² groups. The authors concluded that an effect of microwave treatment on barrier permeability cannot be concluded.
Albert, E.N. · 1978
Researchers exposed adult Wistar rats and Chinese hamsters to continuous-wave microwave irradiation at 2450 and 2800 MHz at 10 mW/cm² for 2 hours. Horseradish peroxidase was injected intravenously to identify brain areas with increased blood-brain barrier permeability. Electron microscopy revealed endothelial cells flooded with peroxidase, swollen astrocytic end feet, myelin figures in dendrites, membranous proliferation in dendrites, and platelet microthrombi in capillaries. Light microscopy showed edematous neuropil surrounding leaky vessels.
Harry D. Muller · 1978
The study describes recent development of rodent control devices that reputedly work by electromagnetic charging of the ground or structures. Rodent damage was estimated at $25 per rat and $4 per mouse, and chemical control poses residue risks in meat, eggs, or manure. Devices initially evoked increased burrowing followed by atypical behavior including distorted diet patterns, burrow avoidance, lethargy, reduced reproduction, anorexia, and hypo-activity resulting in death.
R.P. Liburdy · 1978
Researchers used a novel double-isotope labeling technique with Cr-51 labeled T-lymphocytes and In-111-oxine labeled B-lymphocytes, mixed the fractions, injected them intravenously into female Balb/c mice, and immediately exposed the mice to 2.5 GHz microwave radiation at 30 mW/cm² (45 W/g SAR) for 30 minutes at 25°C. At 30 mW/cm², T-lymphocytes showed a significant increase in migration to the lung, liver, and bone marrow and a marked reduction in migration to the spleen. B-lymphocytes were essentially unaffected by microwave irradiation.
Unknown authors · 1978
WIESLAW WIKTOR-JEDRZEJCZAK et al. · 1977
A single exposure significantly increased the proportion of complement-receptor-positive lymphoid cells in the spleen on day 6, with a net increase of 33.5%. Repeated exposures on three days significantly increased complement-receptor-positive cells on days 3, 6, and 9, and also significantly increased immunoglobulin-positive cells on day 6. Total spleen cell numbers and theta-positive cell proportions did not change after either single or repeated exposures.
Kinn JB · 1977
Tikhonchuk VS · 1977
T. A. Perumal, T. K. Bullard, C. Jayachandran · 1977
Researchers immobilized one hind limb of rats in a plaster cast with brass plate electrodes and applied electric pulses for six hours daily over 21 days. Tibia from both limbs were measured for dry weight, ash content, new bone deposition rate, and x-ray density. Electric fields decreased the degree of disuse bone atrophy caused by immobilization.
R. H. Lenox, J. L. Meyerhoff, O. P. Gandhi, H. L. Wray · 1977
Researchers varied microwave exposure configuration and output power to inactivate brain enzymes in rats. They studied the rate of metabolic inactivation in various brain regions by measuring cyclic AMP and phosphodiesterase activity. Exposure times needed to stabilize cyclic AMP levels differed among the hypothalamus, cortex, and cerebellum. Cyclic AMP levels in some regions decreased when inactivation was more rapid.
Sol M. Michaelson, Ronnie Guillet, Franklin W. Heggeness · 1977
А. Д. Стржижковский, Г. В. Галактионова · 1976
Г. Д. Антимоний et al. · 1976
Ernest N. Albert · 1976
Roberts Rugh, Henry Ho, Mary McManaway · 1976
Roberts Rugh · 1976
Researchers exposed 114 male and female mice of three distinct ages to 2450 MHz microwave radiation at 75 watts forward power until death. Time to death increased with age for both sexes, but the mean absorbed dose at death did not differ significantly with age or weight within the same sex.
J. Eugene Robinson, Duncan McCulloch, Edgar A. Edelsack · 1976
Researchers exposed mammary tumors on mice to 2450 MHz microwaves at up to 200 watts in a free-field setup. Microwave heating alone from room temperature was marginal and produced unacceptably high thermal non-uniformities. Adding warm air to preheat tumors to body core temperature allowed hyperthermic temperatures of 40°C and 43°C with only 30 watts of microwave power. However, the maximum temperature deviation within tumors remained about 1.5°C, exceeding the desired uniformity of less than 0.25°C.
James H. Merritt, Richard H. Hartzell, James W. Frazer · 1976
S. J. BAUM et al. · 1976
Unknown authors · 1976
Researchers used whole brain homogenate from unsexed adult Sprague-Dawley rats. For atropine, the bound-to-free ratio fell from near 2 in controls to near 1 in irradiated samples. For acetylcholine, irradiated samples showed a tendency toward lower ratios, but insufficient data prevented a significance test.
