Whitehead TD et al. · 2005
The study aimed to confirm a previous report that CDMA and FDMA radiation increased Fos levels as cells entered plateau phase. Fos mRNA levels were not significantly different from sham exposure at either SAR level for any signal modulation. Therefore, the earlier results could not be confirmed.
Wang J et al. · 2005
Researchers exposed mouse C3H10T1/2 cells to 2450 MHz HFEMF at SARs of 5 to 200 W/kg for 2 hours, with or without methylcholanthrene (MC) and the tumor promoter TPA. Transformed foci of Type II and Type III were counted as the endpoint. No significant differences were observed in malignant transformation frequency between controls and HFEMF with or without TPA. Transformation frequency increased for HFEMF at SAR above 100 W/kg when combined with MC or MC plus TPA, while heat exposure did not increase transformation.
Uloziene I, Uloza V, Gradauskiene E, Saferis V. · 2005
The study aimed to assess potential hearing changes from mobile phone electromagnetic fields at 900 and 1800 MHz. Thirty volunteers aged 18 to 30 with normal hearing participated in a within-subject design. Each participant attended two sessions, one with genuine exposure and one with sham exposure, administered double-blind and counterbalanced. Hearing threshold levels on pure tone audiometry and transient evoked otoacoustic emissions were recorded before and immediately after each 10-minute exposure. Statistical analysis showed no significant differences in mean hearing threshold levels or TEOAE shifts before and after either genuine or sham exposure, average TEOAE levels changed less than 2.5 dB, and the greatest individual change was a 10 dB decrease after real exposure.
Tornros JE, Bolling AK. · 2005
The study examined effects of handheld and handsfree mobile phone dialling and conversation on simulated driving performance. Dialling and conversation both impaired peripheral detection, but dialling increased lateral position deviation while conversation decreased it for both phone modes. Dialling reduced speed most with handsfree, conversation reduced speed only with handheld, and mental workload remained markedly increased despite compensatory speed reductions.
Straume A, Oftedal G, Johnsson A · 2005
One healthy male subject participated in the study. The subject held the phone in a normal position while the phone was off, on with a 50 Ohm load replacing the antenna to remove RF exposure, and on while transmitting RF fields. The phone’s output power was set to its minimum and maximum levels. The experiment was double blind. Skin temperature changes were calculated on the exposed side of the head relative to the unexposed side after 15 and 30 minutes of use.
Sievert U, Eggert S, Pau HW · 2005
Researchers tested 12 healthy people with normal hearing by recording auditory brain stem reflexes before, during, and after exposure to electromagnetic emissions from standardized mobile phone devices. Two modes of electromagnetic emissions fields were used: pulsed and continuous. No impact on auditory brain stem reflexes recordings in terms of absolute and interpeak latencies was found, and the authors concluded no adverse short-term effects on ear function.
Shirai T et al. · 2005
A 1.439 GHz TDMA signal was used for exposure of the rat head starting from 5 weeks of age, 90 min a day, 5 days a week, for 104 weeks. Brain tumorigenesis was initiated by an intrauterine exposure to N-ethylnitrosourea (ENU) on gestational day 18. No increase in the incidences or numbers per group of brain and/or spinal cord tumors, either in the males or females, was detected in the EMF exposed groups. There were no inter-group differences in body weights, food consumption, and survival rates.
Schoemaker MJ et al. · 2005
Researchers conducted six population-based case-control studies in four Nordic countries and the UK to assess acoustic neuroma risk in relation to mobile phone use. Data were collected by personal interview from 678 cases of acoustic neuroma and 3553 controls. The risk of acoustic neuroma in relation to regular mobile phone use was not raised (OR=0.9, 95% CI 0.7-1.1). Risk of a tumour on the same side of the head as reported phone use was raised for use for 10 years or longer (OR=1.8, 95% CI 1.1-3.1).
Schmid G, Sauter C, Stepansky R, Lobentanz IS, Zeitlhofer J · 2005
Researchers exposed 58 healthy volunteers to a generic 1.97 GHz UMTS-like signal in a double-blinded crossover design. Each subject completed four clinical visual perception tests under high exposure, low exposure, and sham conditions. High exposure produced an average SAR of 0.63 W/kg (1 g) and 0.37 W/kg (10 g) in the left temporal cortex. No statistically significant differences in visual perception parameters were found between any exposure condition and sham.
Preece AW et al. · 2005
Researchers tested 18 children aged 10 to 12 years using a randomized three-way crossover design with exposures of 0, 0.025, or 0.25 W from a Nokia 3110 handset. Baseline reaction times were considerably slower than in adults. There was a tendency for shorter reaction times during exposure, most marked for simple reaction time, but no effects reached statistical significance after Bonferroni correction.
Poysti L, Rajalin S, Summala H · 2005
Logistic regression models showed that older age, female gender, smaller amount of driving, occupation, low skill level, and high safety motivation promoted not using a phone at all while driving. Among drivers who used a phone while driving, higher mileage, more extensive phone use, younger age, leading occupational position, and low safety motivation increased phone-related hazards, while gender and driving skill level had no effect.
Pau HW, Sievert U, Eggert S, Wild W · 2005
Researchers applied a simulated GSM signal to one ear at a time while recording video nystagmography in 13 volunteers. No EM radiation-induced nystagmus was recorded in any volunteer. In human temporal bones, very weak caloric effects were only found near the antenna, while the horizontal semicircular canal seemed unaffected with temperature changes below 0.1 degree C.
Ozguner M et al. · 2005
Twenty adult male Sprague-Dawley rats were randomized into a control group and an EMF group exposed to 900 MHz EMF for 30 minutes per day, 5 days a week for 4 weeks. Testicular weight, biopsy score, and interstitial tissue percentage did not differ significantly between groups. Seminiferous tubule diameter and germinal epithelium height were significantly decreased in the EMF group. Serum testosterone was significantly lower in the EMF group, while LH and FSH did not change significantly.
Miyakoshi J et al. · 2005
Researchers exposed human glioma MO54 cells to a continuous wave 1950 MHz RF field at SARs of 1, 2, and 10 W/kg for up to 2 hours. Cell growth was assessed by counting cell numbers up to 4 days after exposure. RF exposure at 2 and 10 W/kg did not affect the growth of MO54 cells. However, exposure at 10 W/kg for 1 and 2 hours significantly decreased the protein level of phosphorylated Hsp27 at serine 78.
Lonn S, Ahlbom A, Hall P, Feychting M. · 2005
Lim HB, Cook GG, Barker AT, Coulton LA. · 2005
Researchers exposed human peripheral blood to 900 MHz fields at specific absorption rates of 0.4, 2.0, and 3.6 W/kg for durations of 20 minutes, 1 hour, and 4 hours. Heat stress at 42 degrees Celsius increased the number of cells expressing HSP70 and HSP27 in a time-dependent manner. No statistically significant difference in stress protein expression was detected after RF-field exposure.
Lee JS, Huang TQ, Lee JJ, Pack JK, Jang JJ, Seo JS. · 2005
Researchers exposed eight-week-old hsp70.1-deficient mice twice daily for 45 minutes with a 15-minute interval, five days a week for ten weeks at a whole-body average specific absorption rate of 0.4 W/Kg for both 849 MHz and 1763 MHz fields. They examined major tissues histopathologically, assessed cell proliferative activity immunocytochemically, measured apoptosis with a TUNEL assay, and evaluated heat shock protein expression and stress-activated kinase phosphorylation by western blot. No histopathological differences were found between sham- and RF-exposed mice, and there was no evidence of increased proliferative or apoptotic activity. Levels of HSP90, HSP70, and HSP25 showed no obvious changes, and RF exposure did not affect phosphorylation of ERK1/2, JNK1/2, or p38 MAPK.
Laszlo et al. · 2005
Researchers measured heat-shock factor DNA-binding activity in hamster, mouse, and human cells after exposure to FDMA- or CDMA-modulated microwaves at low or high SARs. The assay could detect a 10% increase in HSF activation from a 1°C temperature rise. No increase in HSF DNA-binding ability was detected from any exposure tested. The results do not support activation of the stress response by mobile communication microwaves.
Kuribayashi M et al. · 2005
Researchers investigated possible effects of 1439 MHz electromagnetic near field exposure on the blood-brain barrier in immature (4 weeks old) and young (10 weeks old) rats. Expression of the three genes was not pathologically changed by EMF at any exposure level or age, and vascular permeability measured with FITC-dextran FD20 was not affected. The findings suggest that local head exposure to 1439 MHz EMF exerts no adverse effects on the BBB in immature and young rats.
Koyu A, Cesur G, Ozguner F, Akdogan M, Mollaoglu H, Ozen S. · 2005
The study examined effects of 900 MHz EMF on thyroid hormones in adult male Sprague-Dawley rats. Thirty rats were divided into control, EMF-exposed, and sham-exposed groups of ten each. Exposed rats received 30 minutes of EMF per day, five days a week, for four weeks. TSH and T3-T4 levels were significantly lower in the EMF group than in the sham group (p<0.01). No significant differences were found between control and sham groups (p>0.05).
Koyu A et al. · 2005
Researchers studied the effects of 900 MHz and 1800 MHz EMF on nocturnal serum melatonin in adult male Sprague-Dawley rats exposed for 30 minutes per day, five days per week for four weeks. Serum melatonin concentrations were measured at 12:00 pm using a radioimmunoassay method. No statistically significant differences in melatonin levels were found between the 900 MHz exposed group and the sham group, nor between the 1800 MHz exposed group and the sham group.
Komatsubara Y et al. · 2005
Researchers exposed murine m5S cells to 2.45 GHz high-frequency electromagnetic fields for 2 hours at SARs of 5, 10, 20, 50, and 100 W/kg continuous wave and at a mean SAR of 100 W/kg pulse wave with a maximum of 900 W/kg. The effects were compared with sham-exposed controls and with mitomycin C and X-ray treatments as positive controls. No significant differences in chromosomal aberrations were observed between HFEMF-exposed cells and sham controls, while positive controls increased chromatid-type and chromosome-type aberrations.
Iudice A et al. · 2005
Twenty-three young healthy participants completed a 10 km simulated drive under four counterbalanced conditions: alcohol alone, alcohol with 19 h wakefulness, alcohol with 24 h wakefulness, and sober. The combination of alcohol and 24 h wakefulness produced the highest driving impairment, significantly greater than alcohol alone. Alcohol with 19 h wakefulness significantly affected only the time-to-collision measure, while alcohol alone in rested conditions did not significantly change any study measure.
Huang TQ, Lee JS, Kim TH, Pack JK, Jang JJ, Seo JS. · 2005
The study used 80 male ICR mice initiated with DMBA and then exposed to 849 MHz or 1,763 MHz RF radiation at 0.4 W/kg SAR for 19 weeks. No skin tumors were observed in the sham or RF-exposed groups, while the TPA positive control group had a 95% tumor incidence. Pathological examination and PCNA staining showed no differences between sham and RF-exposed groups, and cyclin D1 and c-fos expression was only detected in TPA-induced tumors. The researchers concluded that RF radiation does not act as a tumor promoter for skin tumors in this model.
Hata K et al. · 2005
The study aimed to clarify the effects of short-term 1439 MHz TDMA exposure on melatonin synthesis in rats. Researchers investigated 208 male and female rats with brain SAR of 7.5 W/kg and whole-body SAR of 1.9 to 2.0 W/kg. After a 12-hour light-dark cycle, serum and pineal melatonin and pineal serotonin were measured by radioimmunoassay in darkness. No significant differences in melatonin or serotonin levels were found between exposed, sham, and cage control groups.