Qin F et al. · 2018
Researchers exposed male mice to 1800 MHz radiofrequency fields at 40 μW/cm2 and 0.0553 W/Kg SAR for 2 hours per day over 32 days. The exposure significantly reduced testosterone levels and altered the expression of steroidogenic genes Star, P450scc, P450c17, and 3β-Hsd in testicular tissue. RF exposure also significantly reduced the regulatory protein CaMKI/RORα, and similar effects were observed in cultured primary Leydig cells exposed in vitro. The CaMK inhibitor KN-93 blocked all these observations, and ionomycin reversed the RF-induced down-regulation of intracellular calcium and CaMKI/RORα expression.
Unknown authors · 2018
Researchers irradiated peripheral blood cells from five donors with a continuous wave of 900 MHz RF-EMF for 0, 30, 60 and 90 min and evaluated gene expression changes with microarray analysis. After false discovery rate adjustment, no EMF-specific gene expression response was detected. Low-stringency analysis identified 483 statistically significant deregulated transcripts, but these were regarded as statistical artefacts due to the absence of a targeted biological response, and qRT-PCR of 14 candidate transcripts showed no correlation with microarray results.
Unknown authors · 2018
Unknown authors · 2018
The study aimed to evaluate genotoxic and cellular effects of in vitro exposure of human fetal and adult fibroblasts to microwave radiation at 25 GHz. Comet assay, phosphorylation of H2AX histone, and CREST-negative micronuclei frequency excluded direct DNA damage in exposed fibroblasts. No induction of apoptosis or changes in prosurvival signalling proteins were detected. CREST analysis showed an increase in total micronuclei and centromere-positive micronuclei in exposed samples, indicating aneuploidy induction due to chromosome loss.
Unknown authors · 2018
Recent research focuses on unraveling mechanisms of radiofrequency electromagnetic radiation and potential cellular targets. Omics high-throughput approaches are powerful tools to investigate global effects of radiofrequency electromagnetic radiation on cellular physiology.
Unknown authors · 2018
Researchers exposed female Wistar albino rats to 1800 MHz RF-EMF at 6.8 ± 0.1 V/m and 0.06 W/kg SAR for 2 hours per day for eight weeks, with a sham group kept under similar conditions without exposure. They measured Hsp27, p38MAPK, EGFR, and caspase-3 gene expression using real-time PCR. Caspase-3 and p38MAPK gene expression were significantly upregulated in the ocular tissues of exposed rats.
Unknown authors · 2018
Researchers investigated the impact of the UMTS signal on DNA stability in ten human cell lines at SAR values of 0.25 to 1.00 W/kg. No DNA damage was detected in single cell gel electrophoresis assays when cells were cultivated with serum, but serum-deprived p53-proficient U87 glioblastoma cells showed transient DNA damage and induced nucleotide excision repair without double-strand breaks, while p53-deficient U251 cells showed no effects. The authors concluded that the signal causes transient genetic instability in glioma-derived cells and activates cellular defense systems.
Unknown authors · 2018
The study was carried out on 56 men (age range: 30-60 years old)in four treatment groups with n = 14 in each group, defined as no mobile phone use, 0-30 min/day, 30-60 min/day, and more than 60 min/day. Ear canal hair follicle cells taken from the subjects were analyzed by the Comet Assay to determine DNA damages, measuring head length, tail length, comet length, percentage of head DNA, tail DNA percentage, tail moment, and Olive tail moment. Results of the study showed that DNA damage indicators were higher in the RFR exposure groups than in the control subjects, and DNA damage increased with the daily duration of exposure.
Unknown authors · 2018
Twelve-week old male mice were exposed to 2.45 GHz microwave radiation at 0.0248 mW/cm2 power density and 0.0146 W/kg SAR for two hours daily over 15, 30, and 60 days. Researchers evaluated testicular histology, serum testosterone, ROS, NO, MDA, antioxidant enzymes, and apoptotic protein expression. Exposure induced testicular redox imbalance that enhanced apoptosis via a p53 dependent Bax-caspase-3 pathway with severity increasing with exposure duration.
Unknown authors · 2018
Researchers divided male Wistar-Albino rats into four groups of eight and exposed one group to 2600 MHz EMF for 30 days. EMF exposure increased sinus dilatation, caspase-3 and TNF-α positive cells, and malondialdehyde levels in liver tissue. Quercetin at 100 mg/kg/day did not prevent the liver damage.
Unknown authors · 2018
Researchers exposed female rats to a continuous 900-MHz electromagnetic field for one hour daily from postnatal day 35 to 59. Control, sham, and EMF groups were established, with sham rats receiving a pseudo-megahertz effect. All animals were euthanized on postnatal day 60 and kidney tissues were analyzed for histopathology and oxidative stress markers. Histopathological analysis showed no pathology in control or sham groups, but the EMF group exhibited hemorrhage in glomeruli, vacuolization and irregularity in tubular epithelium, glomerular degeneration and edema, Bowman capsule degeneration, medullary hemorrhage, disturbed nuclei, and cortical tubular edema. Total oxidant status and oxidative stress index values were significantly lower in both EMF and sham groups compared with controls.
Unknown authors · 2018
Male albino Wistar rats were exposed to 900 MHz radiation for 1 hour per day at a power density of 146.60 µW/cm2 from a mobile phone for 28 days. MDA concentration was increased but TA levels and GST activity were not different in the exposed group compared to controls. Sperm motility was slightly reduced and percentage of abnormal sperm was significantly elevated in the exposed group. Loss of germ cells, particularly spermatocytes and spermatids, was found in the testes of exposed rats, and testes caspase-3 activity was slightly elevated.
Unknown authors · 2018
Mice were exposed to 2.45 GHz microwave radiation at a power density of 0.25 mW/cm2 and SAR of 0.09 W/kg for 2 hours per day over 30 days. Exposure significantly increased catalase, malondialdehyde, and reactive oxygen species while decreasing glutathione peroxidase, testosterone, and superoxide dismutase levels. Flow cytometry revealed micronuclei formation in the blood of exposed mice, and histopathological changes were observed in seminiferous tubules.
Unknown authors · 2018
Researchers randomly assigned rats to cage control, sham, or 2.1 GHz RF exposure for 2 hours daily over 7 days and recorded auditory evoked potentials. Peak-to-peak amplitudes of auditory evoked potentials were significantly higher in the RF group than in the sham group. Evoked power, inter-trial phase synchronization, and auditory evoked gamma responses were also significantly higher in the RF group. The RF group showed significantly lower TBARS and 4-HNE levels, while GFAP, nNOS, and iNOS levels did not differ between groups, and no differences were found between cage control and RF groups.
Hancı H, Kerimoğlu G, Mercantepe T, Odacı E · 2018
Twenty-four Sprague Dawley rats aged 21 days were randomly divided into three groups, and the EMF group rats were exposed to continuous 900-MHz EMF for 1 h each day during adolescence. The results showed that changes may occur in morphology and oxidative stress biomarkers in the rat testis after such exposure.
Unknown authors · 2018
Unknown authors · 2018
They measured reduced glutathione (GSH) and malondialdehyde (MDA) in kidney tissue and used caspase-3 immunohistochemistry to assess apoptosis. Deterioration was observed in the brush border in renal tubules of the EMF groups. The immunohistochemical analysis revealed a greater number of positively stained renal tubular epithelial cells in the EMF groups compared with the control group. In the EMF groups renal MDA levels increased and renal GSH levels decreased compared with the control group (p = 0.00 for both).
Hinrikus H et al · 2018
The review analyzes theoretical and experimental results to explain how low-level microwave radiation affects biological systems. The proposed mechanism states that microwave radiation rotates dipolar molecules, which polarizes the dielectric medium and restructures hydrogen bonds. Weakened hydrogen bonds then decrease viscosity and enhance diffusion at constant temperature. The model's steps have no critical frequency restrictions at microwave frequencies and are supported by electromagnetic field theory and published experiments.
Huss A et al · 2018
Researchers performed a meta-analysis of 20 epidemiologic studies to examine the association between occupational ELF-MF exposure and ALS. Overall, higher occupational ELF-MF exposure was associated with a slightly increased ALS risk (sRR 1.14, 95% CI 1.00–1.30), and electrical occupations showed a higher risk (sRR 1.41, CI 1.05–1.92), but there was large heterogeneity between studies (I2 > 70%). Studies using self-reported exposure or death certificates did not find increased risks, while studies assessing the whole occupational history with highest-longest exposure metrics found a stronger association (sRR 1.89, CI 1.31–2.73) compared to those using only few time points (sRR 1.06, CI 0.75–1.57).
Unknown authors · 2018
The study analyzed extremely low-frequency magnetic fields from 3163 datasets collected in 100 Australian houses across different geographical locations. Average geometric mean magnetic fields were 0.85 mG at beds, 1.39 mG in bedrooms, 0.39 mG at baby cots, 0.47 mG in children's play areas, and 0.30 mG in family rooms. Measurements showed considerable variation, with 21.83% of bed measurements and 33.33% of bedroom measurements exceeding 4 mG, and some emissions surpassed ICNIRP general public exposure limits. Away from electrical appliances, average fields in all rooms ranged from 0.30 to 1.39 mG. The authors suggest simple precautions can reduce exposure and propose their data collection model for future surveys.
Shepherd S et al · 2018
Researchers tested how acute exposure to 50 Hz ELF EMFs at levels ranging from 20–100 µT, found at ground level below powerline conductors, to 1000–7000 µT, found within 1 m of the conductors, affects honey bee olfactory learning, flight, foraging activity and feeding. Exposure reduced learning, altered flight dynamics, and reduced the success of foraging flights towards food sources.
Juutilainen J et al et al. · 2018
Extremely low-frequency magnetic fields have been classified as possibly carcinogenic based on epidemiological findings suggesting a link between childhood leukaemia and 50–60 Hz magnetic fields from power lines. Animal and in vitro experiments have provided only limited support for carcinogenic effects of ELF magnetic fields. The review discusses the radical pair mechanism as a possible biophysical mechanism and proposes a hypothesis for the link between ELF fields and childhood leukaemia.
Unknown authors · 2018
Twenty-four 34-day-old female Sprague-Dawley rats were divided into control, sham, and EMF exposure groups. The EMF group received 900-MHz electromagnetic field exposure for 1 hour daily from postnatal days 35 to 59. Ovarian tissue in the EMF group showed thinning of granulosa and theca layers, shrunken granulosa cells, reduced mitotic activity, and leukocyte infiltration. Secondary follicle counts were significantly lower in the EMF group than in the control or sham groups. Biochemical analysis found increased oxidative stress markers and antioxidant enzymes in both EMF and sham groups compared to controls, with the EMF group showing the highest total oxidant status and oxidative stress index.
Unknown authors · 2018
Hardell L et al · 2018
Researchers measured RF radiation levels in an apartment close to two groups of mobile phone base stations on the roof. A total of 74,531 measurements were made corresponding to ~83 h of recording. The total mean RF radiation level was 3,811 µW/m2 with a range of 15.2 to 112,318 µW/m2 for the whole apartment including balconies. Particularly high levels were measured on three balconies and three of the four bedrooms. The mean RF radiation level decreased by 98% when down-links from the base stations for 2, 3 and 4 G were disregarded.
