Odacı E et al. · 2013
Researchers exposed pregnant rats to 900 MHz electromagnetic fields for one hour daily between days 13 and 21 of pregnancy, then assessed the female pups' spinal cord tissue and motor behavior. The rotarod test showed a significant increase in motor functions in the EMF group pups (p=0.037), while the open field test found no difference between groups. Pathological changes were observed in the spinal cords of the EMF group pups, and the researchers suggested these changes may have led to the increase in motor activity.
Baş O et al. · 2013
Researchers exposed pregnant rats to a 900 MHz electromagnetic field on days 13 through 21 of pregnancy, then examined the brains of their female pups on postnatal day 32. Exposure during those prenatal days led to a significant decrease in the number of pyramidal cells in the cornu ammonis of the female rat pups (P<0.05). Histopathological examination also revealed picnotic cells in the cornu ammonis of the exposed female rat pups.
Guler G, Tomruk A, Ozgur E, Seyhan N. · 2010
Researchers investigated oxidative DNA damage and lipid peroxidation levels in the brain tissue of pregnant and non-pregnant New Zealand White rabbits and their newborns exposed to radiofrequency radiation. The rabbits were exposed to radiofrequency radiation at 1800 MHz GSM at 14 V/m for 15 minutes per day over 7 days. MDA and 8-OHdG levels in exposed pregnant and non-pregnant rabbits were significantly increased compared to controls, but no difference was found in the newborns.
Campisi A et al. · 2010
Italian researchers exposed brain support cells (astrocytes) to cell phone-frequency radiation (900MHz) at levels similar to what phones emit. After just 20 minutes of exposure to modulated signals, the cells showed increased cellular damage and DNA fragmentation, while continuous waves caused no effects. This suggests that the pulsing pattern of wireless signals, not just their intensity, may be what causes biological harm.
Campisi A et al. · 2010
Researchers exposed primary rat neocortical astroglial cell cultures to electromagnetic fields in the microwave range, either as continuous waves or amplitude-modulated at 50 Hz, for 5, 10, or 20 minutes. A significant increase in ROS levels and DNA fragmentation was found only after exposure of the astrocytes to modulated EMF for 20 min. Cell viability was not affected, and the irradiation conditions allowed the exclusion of any possible thermal effect.
Furubayashi T et al. · 2009
Researchers conducted a double-blind, cross-over study with 11 women reporting mobile phone related symptoms and 43 control women. Participants were exposed to 2.14 GHz W-CDMA fields at 10 V/m for 30 minutes under continuous, intermittent, and sham conditions. The symptom group did not detect real exposure better than controls but reported more discomfort during both real and sham exposure, with no differences in psychological, cognitive, or autonomic measures.
Tkalec M et al. · 2009
Researchers exposed Allium cepa seeds for two hours to 400 and 900MHz fields at strengths of 10, 23, 41 and 120Vm(-1), and also tested a four-hour exposure and modulation at 23Vm(-1). Germination rate and root length did not change significantly under any exposure condition. At 900MHz, higher field strengths (41 and 120Vm(-1)) and modulated fields significantly increased the mitotic index, while all 900MHz exposures increased the percentage of mitotic abnormalities. At 400MHz, the mitotic index increased only after modulated exposure, and higher numbers of mitotic abnormalities were found after modulated exposure and after higher field strengths (41 and 120Vm(-1)). The chromosomal aberrations were mainly lagging chromosomes, vagrants, disturbed anaphases and chromosome stickiness.
Furubayashi T et al. · 2009
Researchers exposed 54 women (including 11 with self-reported electromagnetic hypersensitivity) to cell tower radiation at 10 V/m for 30 minutes in a controlled lab setting. Neither group could detect when they were actually being exposed to EMF, and both groups showed identical biological responses whether exposed to real or fake radiation. The study found no evidence that people with electromagnetic hypersensitivity react differently to cell tower emissions than healthy controls.
Tkalec M, Malarić K, Pevalek-Kozlina B. · 2007
Researchers exposed duckweed (Lemna minor) to radiofrequency electromagnetic fields at 400 and 900 MHz, at field strengths of 10, 23, 41, and 120 V m−1, for 2 hours, and also tested a longer 4-hour exposure and modulated fields. After exposure, the researchers measured lipid peroxidation, H2O2 content, antioxidative enzyme activities and isoenzyme patterns, and HSP70 expression. At 900 MHz, almost all exposure treatments significantly increased lipid peroxidation and H2O2 content, mostly decreased PPX activity, and did not affect CAT activity. No differences in isoenzyme patterns of antioxidative enzymes or HSP70 level were found between control and exposed plants at either frequency.
Unknown authors · 1982
W. R. Adey · 1975
Studies reported behavioral effects including shortening of human reaction times, of human circadian rhythms, and of subjective estimates of the passage of time in the monkey, using electric fields at 5-15 Hz with a peak amplitude of 2-10 V/m in air. There was a remarkable tuning curve for different modulation frequencies, with increased calcium efflux from the cortex at modulation frequencies between 9 and 20 Hz, but very little increase outside this frequency band. Pulsed electric stimulation of cat cortex with gradients in the range 20-60 mV/cm increased the efflux of both calcium and GABA.
Karel Marha · 1970
Nazıroğlu M et al. · 2012
Researchers divided rats into four groups: a cage control, a sham control, a group exposed to 2.45 GHz electromagnetic radiation, and a group exposed to the same radiation while also receiving melatonin. The radiation-exposed groups received that exposure for 60 minutes per day for 30 days, after which brain cortex and dorsal root ganglion samples and EEG recordings were collected. Lipid peroxidation, cell viability, and cytosolic calcium values in dorsal root ganglion neurons were higher in the radiation-only group than in the control groups. The melatonin-plus-radiation group showed lower EEG spike numbers and higher brain cortex vitamin E concentration compared with the radiation-only group.
Nittby H et al. · 2008
Swedish researchers exposed rats to cell phone radiation at 1,800 MHz for six hours and found significant changes in brain gene expression. The radiation altered genes controlling cell membranes and signal transmission in memory-critical brain regions, occurring at levels similar to extended human cell phone use.
Ntzouni MP et al. · 2013
Sirav B, Seyhan N · 2009
Researchers investigated the effects of 900 and 1,800 MHz continuous-wave radio frequency radiation on blood-brain barrier permeability in rats. Twenty minutes of exposure at both frequencies increased blood-brain barrier permeability in male rats, while female rats showed no change. The researchers noted that the scientific evidence on radio frequency radiation safety or harm remains inconclusive.
Türedi S et al. · 2014
Researchers exposed pregnant rats to a 900 MHz electromagnetic field for one hour per day on days 13 to 21 of pregnancy, then examined the hearts of male rat pups on postnatal day 21. The mean electrical field intensity inside the exposure box was 13.77 V/m. In the exposed group, malondialdehyde, superoxide dismutase, and catalase values were significantly higher, while glutathione values were lower. Microscopy revealed irregularities in heart muscle fibers, apoptotic changes, mitochondrial swelling and crista loss, myofibril degeneration, and structural impairments in Z bands.
Esmekaya MA et al. · 2016
Researchers studied whether cellular phone radiation affects oxidative stress and nitric oxide levels in mouse brain during epileptic seizures induced by pentylenetetrazole (PTZ). Eight-week-old mice were divided into groups: a PTZ-only control group, a group exposed to 15 minutes of radiation before and 30 minutes after PTZ treatment, and a group exposed to 30 minutes of radiation before and 30 minutes after PTZ treatment. Lipid peroxidation and nitric oxide levels increased significantly in the radiation-exposed groups compared to the control group, while glutathione levels were significantly lower in those same groups.
Hekmat A, Saboury AA, Moosavi-Movahedi AA. · 2012
Researchers exposed calf thymus DNA to mobile phone radiofrequency fields at 940 MHz, 15 V/m, and a SAR of 40 mW/kg, then examined the DNA immediately after exposure and again two hours after a 45-minute exposure using several laboratory instruments. UV-vis and circular dichroism experiments showed that the EMFs caused disturbance in the DNA structure. Exposed DNA samples were relatively thermally unstable compared to unexposed DNA, and showed more fluorescence emission, which the researchers suggested may have occurred due to expansion of the exposed DNA structure. The structure of the DNA immediately after exposure was not significantly different from the DNA sample two hours after the 45-minute exposure, suggesting the changes were irreversible.
Fragopoulou AF et al. · 2012
Researchers investigated the effects of two sources of electromagnetic fields on the proteome of the cerebellum, hippocampus, and frontal lobe in Balb/c mice following long-term whole body irradiation. Across both exposure types, 143 proteins showed significantly altered expression, ranging from as low as 0.003 fold downregulation up to 114 fold overexpression. The altered proteins included neural function related proteins, heat shock proteins, cytoskeletal proteins, and proteins of brain metabolism across nearly all brain regions studied.
Eris AH et al. · 2015
Researchers exposed ten male Wistar Albino rats to 900 MHz electromagnetic radiation at 15.14 V/m for 45 minutes and measured blood serotonin and glutamate levels before and after. Blood plasma serotonin and glutamate levels were measured using enzyme immunoassay. A single 45-minute exposure significantly increased blood serotonin levels but did not change glutamate levels.
Şahin D et al. · 2016
The main finding was increased oxidative DNA damage in the brain after 10 days of exposure, while after 40 days oxidative DNA damage was decreased compared to control groups. A decreased level of the lipid peroxidation marker MDA was also observed after 40 days of exposure.
Nittby H et al. · 2012
Researchers exposed 29 land snails of the strain Helix pomatia to GSM electromagnetic fields at 1900 MHz at 48 mW/kg for 1 hour each, while 29 snails served as sham controls. Before and after exposure, snails were placed on a hot plate and the time until they retracted was measured by two blinded observers. GSM-exposed snails were less sensitive to thermal pain compared to sham controls, indicating a significant analgesia (Mann-Whitney p < 0.001).
Dasdag S, Akdag MZ, Ulukaya E, Uzunlar AK, Ocak AR · 2009
The study used 31 Wistar Albino adult male rats, with the exposed group having their heads placed in a carousel and exposed to 900 MHz microwave radiation for 2 hours per day, 7 days a week, for 10 months. The apoptosis score in exposed rats was significantly lower than in both the sham group and the cage control group. Total antioxidant capacity and catalase were higher in the exposed group than in the sham group, while the oxidative stress index showed no significant difference between those groups. The protein p53 was not significantly changed by the exposure.
Dragicevic N et al. · 2011
Researchers evaluated brain mitochondrial function in aged Alzheimer's transgenic mice and normal littermates following one month of daily EMF exposure. In the transgenic mice, EMF treatment enhanced brain mitochondrial function by 50-150% across six established measures, with the greatest effects in the cerebral cortex and hippocampus. EMF treatment also increased brain mitochondrial function in normal aged mice, though the enhancement was not as robust or widespread as in the transgenic mice. The researchers suggested that brain mitochondrial enhancement may be a primary mechanism through which EMF treatment provides cognitive benefit to both transgenic and normal mice.
