3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.
All Exposure Types

SAR (Specific Absorption Rate)

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Specific Absorption Rate (SAR) measures the rate at which RF energy is absorbed by body tissue, expressed in watts per kilogram (W/kg). SAR is used to rate cell phones and other devices held against the body. The FCC limit for cell phones is 1.6 W/kg averaged over 1 gram of tissue.

Concern Level Thresholds

Based on Building Biology Institute guidelines (W/kg (watts per kilogram)):

No Concern
< 0.4 W/kg
Slight Concern
0.4 – 1.0 W/kg
Severe Concern
1.0 – 1.6 W/kg
Extreme Concern
> 1.6 W/kg (FCC limit)

See where common exposures fall on the scale:

Your RF Exposure in ContextA logarithmic scale showing your reading relative to Building Biology concern thresholds and FCC regulatory limits.Your RF Exposure in ContextNo ConcernSlightSevereExtreme0.0010.010.1FCC Limit 0.00110 W/kg

Showing 871 studies with measured sar (specific absorption rate) exposure

Whole Body / GeneralNo Effects Found

Absence of corneal endothelium injury in non-human primates treated with and without ophthalmologic drugs and exposed to 2.8 GHz pulsed microwaves.

Lu ST et al. · 2010

Researchers exposed four rhesus monkeys to intense 2.8 GHz microwave radiation for 36 hours total over three weeks and measured any damage to the corneal endothelium (the inner layer of cells in the eye's cornea). The study found no changes in corneal cell density or thickness, even at power levels more than ten times higher than previous studies that reported eye damage. This suggests that microwave exposure at these levels may not harm this specific part of the eye.

Brain & Nervous SystemNo Effects Found

Effects of 1950 MHz radiofrequency electromagnetic fields on Aβ processing in human neuroblastoma and mouse hippocampal neuronal cells.

Park J, Kwon JH, Kim N, Song K · 2017

Researchers exposed brain cells to cell phone radiation (1950 MHz) for 2 hours daily over 3 days to see if it affected amyloid-beta processing, which is linked to Alzheimer's disease. They found no significant changes in the proteins that create these brain plaques. However, the researchers noted that longer-term exposure might produce different results than their short 3-day study.

Neurobiological effects of repeated radiofrequency exposures in male senescent rats.

Bouji M, Lecomte A, Gamez C, Blazy K, Villégier AS. · 2016

Researchers exposed both young and elderly rats to cell phone radiation (900 MHz) for 45 minutes daily over one month to see if aging brains were more vulnerable to EMF effects. The study found that while elderly rats showed expected age-related brain problems, the radiation exposure didn't make these problems worse. Interestingly, both young and old rats exposed to radiation showed reduced anxiety-like behaviors.

Exposure to 2.45 GHz electromagnetic fields elicits an HSP-related stress response in rat hippocampus.

Yang XS, He GL, Hao YT, Xiao Y, Chen CH, Zhang GB, Yu ZP. · 2012

Researchers exposed rats to 2.45 GHz electromagnetic fields (the same frequency as WiFi and microwave ovens) and found that their brain cells produced stress proteins in response. The hippocampus, a brain region crucial for memory and learning, showed increased levels of heat shock proteins (HSP27 and HSP70), which cells produce when they're under stress. This provides direct biological evidence that EMF exposure triggers a stress response in brain tissue.

Exposure to 2.45 GHz electromagnetic fields elicits an HSP-related stress response in rat hippocampus.

Yang XS, He GL, Hao YT, Xiao Y, Chen CH, Zhang GB, Yu ZP. · 2012

Researchers exposed rats to WiFi-frequency radiation (2.45 GHz) for 20 minutes and found it triggered stress responses in brain cells. The radiation caused neurons in the hippocampus to produce heat shock proteins, indicating cellular damage in the brain region responsible for memory and learning.

Effects of 900MHz radiofrequency on corticosterone, emotional memory and neuroinflammation in middle-aged rats.

Bouji M, Lecomte A, Hode Y, de Seze R, Villégier AS. · 2012

French researchers exposed young and middle-aged rats to cell phone radiation (900 MHz) for 15 minutes to study brain effects. They found that older rats showed increased brain inflammation and enhanced emotional memory, while younger rats had elevated stress hormones. The study reveals that age significantly affects how the brain responds to radiofrequency radiation.

Effects of 900 MHz radiofrequency on corticosterone, emotional memory and neuroinflammation in middle-aged rats

Bouji M, Lecomte A, Hode Y, de Seze R, Villégier AS · 2012

French researchers exposed young and middle-aged rats to 15 minutes of cell phone radiation (900 MHz) at high levels to study brain and stress responses. They found that middle-aged rats showed increased brain inflammation and enhanced emotional memory, while young rats had elevated stress hormone levels. The study reveals that age affects how the brain responds to radiofrequency exposure, with different vulnerabilities at different life stages.

The role of the JAK2-STAT3 pathway in pro-inflammatory responses of EMF-stimulated N9 microglial cells

Yang X, He G, Hao Y, Chen C, Li M, Wang Y, Zhang G, Yu Z · 2010

Researchers exposed brain immune cells called microglia to 2.45 GHz radiofrequency radiation (the same frequency used in WiFi and microwave ovens) for 20 minutes at high intensity. They found that this EMF exposure triggered inflammation in the brain cells by activating a specific molecular pathway called JAK2-STAT3, which led to increased production of inflammatory chemicals. This suggests that EMF exposure may contribute to brain inflammation through well-defined biological mechanisms.

Exposure to GSM 900 MHz electromagnetic fields affects cerebral cytochrome c oxidase activity.

Ammari M, Lecomte A, Sakly M, Abdelmelek H, de-Seze R. · 2008

French researchers exposed rats to cell phone radiation and measured brain enzyme activity. High-intensity exposure (6 W/kg) for 15 minutes daily reduced brain activity in memory and decision-making regions after one week. Lower exposures showed no effects, suggesting intensity matters for brain function.

Effect of a chronic GSM 900MHz exposure on glia in the rat brain.

Ammari M et al. · 2008

French researchers exposed rats to cell phone radiation (900 MHz) for 24 weeks and found that high-level exposure caused persistent brain inflammation. The study measured GFAP, a protein that increases when brain support cells called astrocytes become activated in response to injury or stress. This suggests that chronic cell phone radiation exposure may trigger ongoing inflammatory responses in brain tissue.

Effect of head-only sub-chronic and chronic exposure to 900-MHz GSM electromagnetic fields on spatial memory in rats.

Ammari M et al. · 2008

French researchers exposed rats to 900-MHz cell phone radiation for up to 24 weeks to test whether it would impair their spatial memory and navigation abilities. The rats showed no memory deficits even when exposed to radiation levels 3-12 times higher than typical cell phone use. This suggests that chronic exposure to GSM cell phone signals may not directly damage the brain's memory systems.

Effect of an acute 900MHz GSM exposure on glia in the rat brain: A time-dependent study.

Brillaud E, Piotrowski A, de Seze R. · 2007

French researchers exposed rats to cell phone radiation (900MHz GSM signal) for just 15 minutes and then examined their brains over the following 10 days. They found significant increases in glial cell activity (brain cells that support and protect neurons) in multiple brain regions, peaking 2-3 days after exposure. This glial response indicates the brain was reacting to the radiation exposure as if responding to injury or stress.

Acute exposure to GSM 900-MHz electromagnetic fields induces glial reactivity and biochemical modifications in the rat brain

Mausset-Bonnefont AL et al. · 2004

French researchers exposed rats to cell phone radiation (900 MHz GSM) for just 15 minutes and found immediate brain damage. The exposure triggered a strong inflammatory response from brain support cells (glial reaction) and disrupted key brain chemical systems involved in movement, memory, and mood. Despite these cellular changes, the rats showed no obvious behavioral problems in the short term.

Human exposure at two radio frequencies (450 and 2450 MHz): similarities and differences in physiological response.

Adair ER, Cobb BL, Mylacraine KS, Kelleher SA, · 1999

Researchers exposed 14 volunteers to radio frequency radiation at 450 and 2450 MHz (similar to cell phone frequencies) for 45 minutes at power levels exceeding current safety guidelines. The exposure caused measurable increases in skin temperature, with the body responding through increased sweating and blood flow to maintain normal core body temperature within 0.1 degrees Celsius.

Interaction of low level modulated RF radiation with Na+¯K+-ATPase.

Behari J, Kunjilwar KK, and Pyne S · 1998

Researchers exposed developing rats to radiofrequency radiation similar to what cell phones emit and found it significantly increased activity of a critical brain enzyme called Na+-K+-ATPase by 15-20%. This enzyme is essential for nerve cell function and brain development. The findings suggest that RF radiation can alter fundamental brain chemistry in developing animals, raising concerns about potential effects on brain development in children.

STAT3 signalling pathway is involved in the activation of microglia induced by 2.45 GHz electromagnetic fields.

Hao Y, Yang X, Chen C, Yuan-Wang, Wang X, Li M, Yu Z · 2010

Researchers exposed brain immune cells called microglia to 2.45 GHz radiation (the same frequency used in WiFi and microwave ovens) for 20 minutes and found it activated these cells through a specific cellular pathway called STAT3. The activated microglia began producing inflammatory molecules including nitric oxide and tumor necrosis factor-alpha. This matters because microglial activation is linked to brain inflammation and neurological problems.

DNA & Genetic DamageNo Effects Found

Cytogenetic investigations on microwavesemitted by a 455.7 MHz car phone

Maes A, Collier M, Verschaeve L · 2000

Belgian researchers exposed human immune cells (lymphocytes) to radiation from a 455.7 MHz car phone at high intensity levels (6.5 W/kg SAR) to see if it would cause genetic damage or make the cells more vulnerable to other cancer-causing agents. They found no evidence that the phone radiation caused chromosome damage on its own, nor did it increase the harmful effects when combined with known mutagens like chemicals or X-rays.

Effects on protein kinase C and gene expression in a human mast cell line, HMC-1, following microwave exposure.

Harvey C, French PW. · 2000

Researchers exposed human immune cells (mast cells) to microwave radiation at 864.3 MHz for 20 minutes daily over a week, using power levels that kept the cells cooler than body temperature. They found that this non-thermal exposure altered the activity of protein kinase C (a key cellular signaling molecule) and changed the expression of three genes, including one linked to cancer development and another associated with cell death.

NF-κB DNA-binding activity after high peak power pulsed microwave (8.2 GHz) exposure of normal human monocytes

Natarajan M, Vijayalaxmi , Szilagyi M, Roldan FN, Meltz ML · 2002

Researchers exposed human immune cells called monocytes to high-powered pulsed microwave radiation at 8.2 GHz for 90 minutes and measured changes in their cellular activity. They found that the radiation triggered a 3.6-fold increase in the activity of NF-κB, a crucial protein that controls genes involved in inflammation, immune responses, and cell survival. This demonstrates that microwave radiation can activate important cellular signaling pathways that regulate long-term cellular functions.

Brain & Nervous SystemNo Effects Found

Local exposure of 849 MHz and 1763 MHz radiofrequency radiation to mouse heads does not induce cell death or cell proliferation in brain.

Kim TH et al. · 2008

Researchers exposed mice to cell phone radiation at 849 MHz and 1763 MHz frequencies for up to 12 months, using radiation levels about 4 times higher than current safety limits. They found no changes in brain cell death, cell growth, or tissue damage compared to unexposed mice. This suggests that chronic exposure to these specific frequencies at high levels may not cause detectable brain tissue changes in mice.