Rostami A et al. · 2016
Researchers exposed male rats to 3 Hz and 60 Hz ELF/EMF using a protocol of two cycles of 2 hours per day for four days with a two-day interval. Immediately after exposure, locomotor activity was significantly lower in both exposed groups compared with sham-exposed rats. The exposure did not change anxiety-like behavior or short-term memory over the following two weeks. Electrophysiological recording showed a significant reduction in locus coeruleus firing rate after two hours of exposure. Proteomic analysis indicated global changes in the whole brain proteome after treatment.
Reale M et al. · 2016
Researchers exposed SH-SY5Y neuroblastoma cells to 50 Hz/1 mT ELF-EMF for short (1h-3h) and sub-chronic (48 h) periods. Exposed cells showed an increased intracellular 5-hydroxyindoleacetic acid/5-hydroxytryptamine ratio reflecting transmitter synthesis, catabolism, and release. Matrix metalloproteinases involved in neuronal cell death were not significantly altered. The balance between reactive oxygen species generation and elimination, and between pro- and anti-inflammatory cytokines, was maintained. The changes were minor compared to damage expected to underlie neurodegeneration or cognitive impairment.
D'Angelo C et al · 2015
Researchers studied MCP-1 expression in HaCaT, SH-SY5Y, THP-1, and K562 cells exposed to a sinusoidal EMF at 50 Hz with a flux density of 1 mT (rms). Preliminary results showed that EMF exposure differently modifies MCP-1 expression in different cell types. The authors state that MCP-1 expression needs to be better determined with additional studies using different parameters and exposure times.
D'Angelo C et al · 2015
Italian researchers exposed four different types of human cells to 50 Hz electromagnetic fields (the same frequency as power lines) at 1 milliTesla strength. They found that this exposure changed the production of MCP-1, a protein involved in immune response and inflammation, but the effects varied depending on the cell type. This suggests that power-frequency EMFs can trigger biological responses in human cells, though more research is needed to understand the health implications.
Ghosn R et al. · 2015
Researchers exposed 26 healthy young adults to radiofrequency signals from a mobile phone while measuring their brain activity using EEG (electroencephalogram). They found that RF exposure significantly reduced alpha brain waves (8-12 Hz), which are associated with relaxed, alert states, and this effect persisted even after the exposure ended. The study carefully controlled for other factors like stress hormones and caffeine that could influence brain activity.
Benassi B et al. · 2015
Researchers exposed human brain cells to 50 Hz magnetic fields (the same frequency as power lines) and found that while the fields didn't harm the cells directly, they made the cells much more vulnerable to a chemical toxin that causes Parkinson's disease-like damage. The magnetic field exposure disrupted the cells' natural antioxidant defenses, causing normally survivable toxin levels to trigger cell death through oxidative stress.
Unknown authors · 2015
Researchers exposed mouse spermatocyte-derived GC-2 cells to 50 Hz ELF-EMF at 1, 2, and 3 mT intermittently for 72 hours. Genome-wide methylation decreased at 1 mT but was higher at 3 mT compared to controls. DNMT1 and DNMT3b expression decreased at 1 mT and increased at 3 mT, while DNMT3a expression was largely unaffected. The researchers also established DNA methylation and gene expression profiling and validated some genes with aberrant methylation and expression at different intensities.
Liu X et al. · 2015
Researchers studied the effects of ELF-EMF exposure on Alzheimer's disease development in rats. The rats were exposed to ELF-EMF at 50 Hz and 400 µT for 60 days. ELF-EMF exposure delayed the weight gain of rats and partially improved cognitive and clinicopathologic symptoms. The researchers concluded that certain conditions of ELF-EMF exposure could delay the development of AD in rats.
Unknown authors · 2015
Researchers exposed HaCaT human keratinocytes to ELF-EMF at 50 Hz and 1 mT and monitored cell cycle, growth, and viability using FACS and BrdU assays. They also measured gene expression changes with microarray and qRT-PCR, and assessed mTOR, Akt, and MAPK protein levels by Western blot. Short ELF-EMF exposure modulated gene expression patterns involved in cell proliferation and the cell cycle, with mTOR activation identified as the main molecular target. The data showed increased PI3K/Akt pathway activity and ERK signaling activation. ELF-EMF selectively modulated multiple genes related to biological processes such as wound healing.
Zhang Y, Liu X, Zhang J, Li N. · 2015
Researchers exposed rats to extremely low frequency electromagnetic fields (the type emitted by power lines and electrical devices) for 12 weeks to see if it would affect memory and brain health, particularly markers associated with Alzheimer's disease. They found no changes in the rats' memory performance, brain tissue structure, or levels of amyloid-beta proteins that are linked to Alzheimer's. This suggests that short-term exposure to these fields at the levels tested did not harm cognitive function in this animal model.
Manzella N et al · 2015
Researchers investigated effects of ELF magnetic fields on circadian clock genes in a human fibroblast cell line. An ELF-MF exposure at 0.1 mT and 50 Hz entrained expression of clock genes BMAL1, PER2, PER3, CRY1, and CRY2. ELF-MF treatment also altered circadian clock gene expression previously entrained by serum shock stimulation.
Unknown authors · 2015
Researchers exposed human skin cells to extremely low frequency magnetic fields (50 Hz, 0.1 mT) and found these fields could reset the cells' internal biological clocks by altering the expression of key circadian genes. The magnetic field exposure changed the timing of five different clock genes, including BMAL1, PER2, PER3, CRY1, and CRY2. This suggests that EMF exposure from power lines and electrical devices might disrupt our natural daily rhythms at the cellular level.
Unknown authors · 2015
Researchers exposed pregnant mice to a 50 Hz, 500 mG field for one week (12 hours per day) and continued exposure of their offspring for up to 15.5 months, while control mice were not exposed. Mean body weights of exposed male and female mice were significantly decreased compared with controls. Exposed mice showed no increased incidence of liver and lung tumors. In female mice, the incidence of chronic myeloid leukemia was significantly greater in the exposed group (3 of 42, 7%) than in controls. The size of seminiferous tubules in exposed males was significantly smaller than in controls.
Unknown authors · 2015
Researchers used a quasi-experimental design with two pretests before and two posttests after a new high-voltage power line began operation. Residents living within 300 meters, 300-500 meters, and 500-2000 meters of the line participated. Symptom reports and causal beliefs increased significantly more in the closest group compared to those farther away. At baseline, symptom reports were similar across groups, but belief that power lines cause symptoms was already stronger among nearby residents.
Legros A, Modolo J, Brown S, Roberston J, Thomas AW. · 2015
Researchers used functional MRI to look for changes in brain activation in human participants following exposure to a 60 Hz magnetic field. The study found significant changes in task-induced functional brain activation as a consequence of magnetic field exposure, but no impact on task performance. The researchers discussed the possibility that exposure at 60 Hz, 3000 μT may be capable of modulating cortical excitability via a modulation of synaptic plasticity processes.
Unknown authors · 2015
Unknown authors · 2015
The paper describes the cryptochrome hypothesis, which suggests that weak 50/60 Hz magnetic fields could disrupt circadian rhythms by affecting cryptochrome clock function. The hypothesis rests on the premise that Earth-strength static magnetic fields alter the redox balance of cryptochromes and possibly their signaling state.
Unknown authors · 2015
Researchers examined whether weak 50/60 Hz magnetic fields could disrupt circadian rhythms by affecting cryptochrome proteins, which help regulate our body's internal clock. The study tested the basic premise that Earth-strength magnetic fields can alter the chemical balance of cryptochromes in the retina. This research explores a potential biological mechanism for how power line frequencies might affect sleep and circadian health.
Hori T et al · 2015
Yang ML, Ye ZM · 2015
Researchers exposed human osteosarcoma MG-63 cells to a 50 Hz, 1 mT extremely low frequency electromagnetic field (ELF-EMF) for 1, 2 and 3 hours in vitro. ELF-EMF decreased the viability of MG-63 cells, inhibited cell growth, induced cell apoptosis and increased the level of ROS significantly. The apoptosis rate declined significantly after treatment with ROS inhibitor NAC or p38MAPK inhibitor SB203580. The researchers concluded that increased ROS and p38MAPK activation may be involved in the mechanism.
Unknown authors · 2015
Researchers assessed fetal exposure to the full harmonic content of a uniform 50 Hz magnetic field using high-resolution three-dimensional fetal models based on European electricity quality standards. The fundamental frequency component provided the main contribution to induced electric fields in the fetus. Harmonic components added some contributions but their amplitudes were low due to extremely low permitted levels relative to the fundamental. Induced electric field levels were much lower than general public exposure limits when the incident magnetic field was at the maximum permitted level.
Chung YH et al · 2015
Korean researchers exposed rats to 60 Hz magnetic fields (the same frequency as power lines) for 2-5 days and found significant changes in brain neurotransmitters across multiple brain regions. The exposure altered levels of dopamine, serotonin, norepinephrine, and other brain chemicals that control mood, movement, and cognitive function. These findings suggest that everyday exposure to power line frequencies may directly affect brain chemistry.
Ross CL, Teli T, Harrison BS. · 2015
Researchers stimulated cAMP in CHO cells transfected with human mu-opioid receptors and exposed them to 5 Hz EMF. The 5 Hz EMF produced 23% greater inhibition of cAMP-treating cells than morphine treatment. When tested at 13 Hz, EMF produced results similar to controls.
Lewicka M et al. · 2015
Unknown authors · 2015
