Unknown authors · 2023
Fifty-six rats weighing 200–250 g were divided into healthy and diabetic groups, each with sham and radiofrequency radiation exposure at 900, 1800, and 2100 MHz. Over a month, each group spent two hours per day in a Plexiglas carousel, with experimental groups exposed to radiofrequency radiation and sham groups not exposed. Researchers performed three-point bending tests and radiological evaluations on the right tibia bones and measured CAT, GSH, MDA, and IMA in skeletal muscle tissue. Significant differences were found in biomechanical properties, radiological evaluations, and muscle tissue measurements between groups (p < .05). Average whole-body SAR values were 0.026 W/kg for GSM 900 MHz, 0.164 W/kg for 1800 MHz, and 0.173 W/kg for 2100 MHz.
Saka VP, Chitra V, Narayanasamy D · 2023
Researchers exposed primary cortical neurons from neonatal rats to electromagnetic radiation from a mobile phone at 2100 MHz and 1.6 W/kg SAR for two hours. The study assessed the induction of apoptosis through modulation of pro- and anti-apoptotic genes via a mitochondrial pathway. Pyrazole derivatives reduced apoptosis by lowering reactive oxygen species and modulating apoptotic gene levels. The compounds showed antioxidative and anti-apoptotic properties.
Unknown authors · 2023
Exposure significantly increased cardiac protein expression of mitochondrial Complex I, II, III, and IV subunits, while Complex V expression remained stable. Mitochondrial respiratory capacity was modified in exposed mice. Oxidative stress markers and antioxidant enzyme SOD2 were unchanged, and no structural or functional heart abnormalities were found.
Unknown authors · 2023
Human keratinocytes were exposed to 900 MHz RF-EMF for 1 hour at a low dose rate (SAR < 10 mW/kg) using a custom system that maintained 37°C, 5% CO2, and 95% humidity. Whole genome bisulfite sequencing was performed directly following exposure to examine immediate changes in DNA methylation patterns and identify early differentially methylated genes. Correlating gene expression with methylation data identified six common targets that were both differentially methylated and differentially expressed, suggesting a potential epigenetic role in the cellular response and that these targets may serve as biomarkers for immediate RF-EMF response.
Saka VP, Chitra V, Narayanasamy D · 2023
Researchers exposed newborn rat brain cells to 2100 MHz cell phone radiation for 2 hours and found it triggered cell death through oxidative stress and mitochondrial damage. However, compounds called pyrazole derivatives protected the brain cells by reducing harmful reactive oxygen species and preventing programmed cell death.
Savchenko L et al. · 2023
Researchers exposed mice to 915 MHz electromagnetic fields (similar to cell phone frequencies) for 28 days and examined heart muscle effects. They found changes in cellular energy production systems within heart mitochondria, but no structural heart damage or oxidative stress markers. The study suggests EMF exposure can alter how heart cells generate energy, though the health implications remain unclear.
Unknown authors · 2023
Researchers exposed pregnant rats to 5G EMF at 3500 MHz continuous wave with a whole-body SAR of 0.07 W/kg for 22 hours per day from gestational day 8 to postnatal day 21. Both male and female pups showed delayed incisor eruption by one day in the exposed group compared to sham controls. In adolescent open-field testing, exposed females exhibited 70% fewer stereotyped movements while exposed males exhibited 50% more stereotyped movements than sham-exposed rats.
Franczak A et al. · 2023
Researchers exposed HeLa, ES-2, and DU-145 cancer cells to 50 Hz ELF-EMF at 1.3 mT for 15 and 30 minutes. The exposure increased reactive oxygen species levels in the cells. ES-2 cells showed upregulation of XRCC5 and higher levels of TNF-α, RAD51, APE1, XRCC1, and NSUN2, while DU-145 cells had reduced BCL-2, HSP90, RAD51, and TNF-α and increased VIM and METTL3.
Unknown authors · 2023
The study used sixty male Sprague-Dawley rats divided into six groups with different ELF-EMF exposure durations. Sperm count and motility were significantly lower in rats exposed for 1 hour per day for 52 days, 4 hours per day for 52 days, and 4 hours per day for 5 days compared with sham-exposed rats. Serum testosterone decreased significantly in rats exposed for 4 hours per day for 5 days. The volume of seminiferous tubules, their epithelium, and interstitial tissue decreased significantly after 4 hours per day for 5 days of exposure. Tubule length was reduced by 18% in the same exposure group.
Kilic A, Ustunova S, Bulut H, Meral I · 2023
Researchers exposed male and female Wistar albino offspring to 900 MHz EMF for one hour per day during prenatal (23 days) and/or postnatal (40 days) periods and collected brain and kidney tissues at puberty. In all exposed groups, total oxidant status, IL-2, IL-6, and TNF-α rose while total antioxidant status fell in both sexes' brain and kidney tissues. Renin-angiotensin system components including angiotensinogen, renin, AT1, AT2, and MAS1-like receptor expression were also elevated in all exposed groups compared with controls.
Kilic A, Ustunova S, Bulut H, Meral I · 2023
Turkish researchers exposed pregnant rats and their offspring to 900 MHz cell phone radiation (the frequency used by GSM networks) for one hour daily. They found significant increases in inflammation, oxidative stress, and activation of the renin-angiotensin system in both brain and kidney tissues of the young rats. The effects occurred whether exposure happened during pregnancy, after birth, or both periods.
Wydorski PJ et al. · 2023
Researchers collected porcine endometrial slices during the peri-implantation period and exposed them to 50 Hz ELF-EMF for 2 hours in vitro. They measured DNA methylation in the promoter regions of EGR2, HSD17B2, ID2, IL1RAP, MRAP2, NOS3, PTGER4, SERPINE1, VDR and ZFP57 using qMS-PCR. Exposure increased methylation of EGR2, ID2, and PTGER4, decreased methylation of IL1RAP and NOS3, and did not change methylation of HSD17B2, MRAP2, SERPINE1, VDR, and ZFP57.
Unknown authors · 2023
Researchers exposed adult male Wistar rats to 50 Hz extremely low-frequency magnetic fields at 1, 1.5, and 2 mT for 4 hours per day, 5 days per week for 30 days. The study found that different exposure levels caused increases in calcium levels and apoptosis in the rat brain. As the magnetic field strength increased, apoptosis and calcium levels in brain tissues also increased. The researchers concluded that the exposure caused neurodegeneration, increased apoptosis, and increased calcium concentration.
Unknown authors · 2023
The study used prepubertal male rats exposed to 2.45 GHz RF radiation at varying electric field intensities. The exposure groups included electric field strengths of 0.6, 1.9, 5, 10, and 15 V/m, with daily 1-hour exposures for 45 days. Exposed rats showed elevated malondialdehyde (MDA) and decreased glutathione (GSH) levels in testicular tissue. Histological analysis revealed distinct alterations in testicular tissue compared to controls.
Unknown authors · 2023
Researchers exposed 28 Wistar Albino rats to 900, 1800, and 2100 MHz radiofrequency radiation for 3 hours per day over one month. The greatest effect was seen at 1800 MHz in the right lobe and at 2100 MHz in the left lobe.
Unknown authors · 2023
Researchers exposed young rats to 2.45 GHz radiation (WiFi frequency) at different intensities for 45 days to study effects on developing reproductive tissue. The study found that stronger radiation caused increased oxidative damage and structural changes in testicular tissue, with the highest exposure level (15 V/m) producing significant harmful effects.
Unknown authors · 2023
Eighty rats were divided into four exposure groups and a control group, and the treatment groups were exposed to 50-Hz magnetic fields at 1, 100, 500, and 2000 μT for 2 hours daily over 60 days. All rats were immunized with human serum albumin on days 31, 44, and 58. AID expression significantly decreased at 1 μT, Bcl-6 expression did not change, and serum IL-6 increased only in the 500 μT group after immunization.
Unknown authors · 2023
Male Sprague Dawley rats were divided into four groups: control, RFR exposure, paricalcitol treatment, and combined RFR plus paricalcitol. No significant differences were found in seminiferous tubule diameters or germinal epithelial thicknesses among groups. Ultrastructural changes observed in the seminiferous tubule and Leydig cells in the RFR group were decreased in the RFR plus paricalcitol group. The RFR plus paricalcitol group showed increased Johnsen Score, Ki67, p63 immunoreactivity, SOD and CAT activities, and decreased MDA levels compared with the RFR group.
Unknown authors · 2023
Researchers exposed Chinese hamster ovary cells to a non-toxic dose of 15-nm gold nanoparticles for 48 hours and then to 900 MHz GSM radiofrequency radiation for 24 hours. The conditioned medium from these cells was transferred to new bystander cells, and cell death, DNA breaks, oxidative stress, and COX-2 expression were measured. RFR increased metabolic death in GNP-treated cells, while colony formation was reduced in bystander cells and RFR-exposed cells regardless of GNP presence. ROS levels were significantly lower in GNP-treated cells, but RFR-induced DNA breaks and micronuclei frequencies were not significantly affected by GNP.
Unknown authors · 2023
Researchers exposed Chinese hamster cells to 900 MHz cell phone radiation in the presence of gold nanoparticles, then transferred the culture medium to unexposed 'bystander' cells. They found that radiation created harmful effects in both directly exposed cells and bystander cells, with gold nanoparticles changing how these effects occurred.
Unknown authors · 2023
CT irradiation had gross effects on platelets, white blood cell counts, memory, hepatic and testicular histoarchitectures compared to the 5 GHz-only group. The 5 GHz-only group showed loss of p53 (exons 5–7) gene bands and increased micronucleated polychromatic erythrocyte count.
Unknown authors · 2023
Unknown authors · 2023
Researchers exposed male rats to 1800 MHz radiofrequency radiation (cell phone frequency) for one hour daily over 30 days, finding it caused testicular damage including cellular changes and increased oxidative stress. When rats received paricalcitol (a vitamin D compound) alongside radiation exposure, the testicular damage was significantly reduced. This suggests certain compounds might help protect reproductive organs from cell phone radiation effects.
Unknown authors · 2023
Weaned Wistar rats were divided into four groups and exposed to EMF (1,760 MHz, 2 h/day) and/or 15% fructose solution for 8 weeks. In the hypothalamic tissue of the combined exposure group, expressions of SIRT1, FOXO1, p-PI3K, p-AKT, Complex III, UCP2, MnSOD, and catalase and activities of OXPHOS and GSH were significantly decreased compared to the normal, EMF-only, and fructose-only groups. In hepatic tissue of the combined exposure group, expressions of p-AMPKα, SIRT1, FOXO1, IRS1, p-PI3K, Complex I, II, III, IV, V, UCP2, and MnSOD and activities of OXPHOS, SOD, catalase, and GSH were significantly reduced compared to the normal group.
Unknown authors · 2023
Researchers exposed growing rats to mobile phone radiation (1,760 MHz) and high-fructose diets for 8 weeks, finding that the combination significantly disrupted metabolic regulation in the brain and liver. The dual exposure impaired insulin signaling, mitochondrial function, and antioxidant defenses more severely than either stressor alone. This suggests that common modern exposures may work together to increase metabolic dysfunction risk during critical developmental periods.
