3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 1,014 studies (Rodent Studies)

Two-year chronic bioassay study of rats exposed to a 1.6 GHz radiofrequency signal.

Anderson LE et al. · 2004

Researchers exposed pregnant rats and their offspring to 1.6 GHz radiofrequency radiation (similar to cell phone signals) for two years to study cancer risk. They found no increased cancer rates or significant health differences between exposed and unexposed animals. This study suggests that long-term exposure to this type of RF radiation at the tested levels may not substantially increase cancer risk in rats.

Oxidative Stress135 citations

Acute exposure to 930 MHz CW electromagnetic radiation in vitro affects reactive oxygen species level in rat lymphocytes treated by iron ions.

Zmyslony M, Politanski P, Rajkowska E, Szymczak W, Jajte J. · 2004

Polish researchers exposed rat immune cells (lymphocytes) to 930 MHz radiation at levels similar to cell phone emissions for 5-15 minutes. While the radiation alone didn't increase harmful free radicals, it significantly amplified free radical production when cells were already under oxidative stress from iron exposure. This suggests cell phone radiation may worsen cellular damage when your immune system is already compromised.

Prevention of mobile phone induced skin tissue changes by melatonin in rat: an experimental study.

Ozguner F, Aydin G, Mollaoglu H, Gokalp O, Koyu A, Cesur G. · 2004

Researchers exposed rats to cell phone radiation at 900 MHz for 30 minutes daily over 10 days and found it caused visible changes to skin tissue, including thickening, cell damage, and altered collagen structure. When rats were given melatonin (a natural hormone) before radiation exposure, most of these skin changes were prevented. This suggests that cell phone radiation can affect skin health, but protective measures may be possible.

Effects of in vitro exposure to power frequency magnetic fields on UV-induced DNA damage of rat lymphocytes.

Zmyślony M et al. · 2004

Polish researchers exposed rat immune cells (lymphocytes) to extremely low frequency magnetic fields at 40 microtesla - similar to levels near power lines - while also exposing them to UV radiation. They found that one-hour magnetic field exposure significantly increased DNA damage beyond what UV alone caused, suggesting the magnetic fields interfered with the cells' natural DNA repair processes.

The effect of weak 50 Hz magnetic fields on the number of free oxygen radicals in rat lymphocytes in vitro

Zmyslony M, Rajkowska E, Mamrot P, Politanski P, Jajte J · 2004

Polish researchers exposed rat immune cells to weak magnetic fields similar to those near power lines. When aligned with Earth's magnetic field, 40 microtesla exposure significantly reduced free radicals - harmful molecules that damage cells. This shows even very weak power-frequency fields can alter basic cellular processes.

Magnetic-field-induced DNA strand breaks in brain cells of the rat.

Lai H, Singh NP · 2004

Researchers exposed rats to extremely low-frequency magnetic fields (the type from power lines) at levels commonly found in homes and workplaces. After 24-48 hours of exposure, they found significant DNA damage in brain cells, with longer exposure causing more damage. The study suggests this damage occurs through iron-mediated free radical formation, potentially leading to brain cell death.

Cancer & TumorsNo Effects Found

Effects of mobile phone radiation on UV-induced skin tumourigenesis in ornithine decarboxylase transgenic and non-transgenic mice.

Heikkinen P et al. · 2003

Finnish researchers exposed mice to mobile phone radiation for one year while also exposing them to UV light to see if the combination would increase skin cancer rates. The mobile phone radiation alone did not significantly increase tumor development, though there was a slight acceleration in tumor growth timing that the researchers noted deserves further investigation.

Immune SystemNo Effects Found

Effects of In Vivo Exposure to GSM-Modulated 900 MHz Radiation on Mouse Peripheral Lymphocytes.

Gatta L et al. · 2003

Researchers exposed mice to cell phone radiation (900 MHz GSM) for 2 hours daily over 1-4 weeks to see if it would affect their immune system cells in the spleen. They found no significant changes in the numbers or types of immune cells, and the cells responded normally when stimulated. The study concluded that cell phone radiation at these levels is unlikely to cause clinically relevant immune system problems.

Brain & Nervous SystemNo Effects Found110 citations

Head-only exposure to GSM 900-MHz electromagnetic fields does not alter rat's memory in spatial and non-spatial tasks.

Dubreuil D, Jay T, Edeline JM. · 2003

Researchers exposed rats to 900 MHz cell phone radiation (GSM signals) for 45 minutes to test whether it affected their memory and learning abilities. The rats performed just as well as unexposed rats on complex maze tests and object recognition tasks, with one group even showing slightly better performance. This suggests that brief exposure to cell phone-level radiation doesn't impair memory function in rats.

Immune SystemNo Effects Found

Effects of GSM-900 microwaves on the experimental allergic encephalomyelitis (EAE) rat model of multiple sclerosis.

Anane R et al. · 2003

Researchers exposed rats with experimental autoimmune encephalomyelitis (EAE), a laboratory model of multiple sclerosis, to 900 MHz cell phone radiation for 2 hours daily over 21 days. The study found no effect of the radiation exposure on the onset, duration, or severity of the autoimmune disease symptoms. This suggests that short-term cell phone radiation exposure may not worsen multiple sclerosis-like conditions, though longer-term effects remain unknown.

Effects of low level pulsed radio frequency fields on induced osteoporosis in rat bone.

Jayanand, Behari J, Lochan R. · 2003

Researchers exposed rats with artificially induced bone loss (osteoporosis) to pulsed radiofrequency fields at 14 MHz. The electromagnetic field exposure significantly increased bone mineral density and slowed the bone breakdown process compared to untreated rats. This suggests certain radiofrequency patterns might have therapeutic potential for treating osteoporosis.

1439 MHz pulsed TDMA fields affect performance of rats in a T-maze task only when body temperature is elevated.

Yamaguchi H et al. · 2003

Researchers exposed rats to cell phone-type radiation (1439 MHz) while testing their ability to learn and remember food locations in a maze. They found that only the highest exposure levels - which caused body temperature to rise - impaired the rats' learning performance. At exposure levels about four times stronger than typical cell phones (but without heating effects), no learning problems occurred.

Protective effect of melatonin and vitamin E against prooxidative action of iron ions and static magnetic field

Jajte J, Zmyślony M, Rajkowska E. · 2003

Researchers exposed rat blood cells to magnetic fields and iron ions to test for cellular damage. The combination significantly increased harmful oxidation in cells, but pre-treating cells with antioxidants like melatonin or vitamin E prevented most damage, suggesting magnetic fields may amplify iron's harmful effects.

DNA & Genetic DamageNo Effects Found

Lack of Mutation Induction with Exposure to 1.5 GHz Electromagnetic Near Fields Used for Cellular Phones in Brains of Big Blue Mice.

Takahashi S et al. · 2002

Researchers exposed mice to 1.5 GHz radiofrequency radiation (the type used in cell phones) for 90 minutes daily over 4 weeks to test whether it could damage DNA in brain cells. They found no evidence of genetic mutations, brain tissue damage, or changes that might lead to brain tumors. The study suggests that cell phone radiation at these levels does not directly cause DNA damage in mouse brain tissue.

Oxidative StressNo Effects Found

Effect of millimeter wave radiation on catalase activity.

Logani MK, Agelan A, Ziskin MC. · 2002

Researchers exposed mice to high-intensity millimeter wave radiation at 42.2 GHz to test whether it could protect an enzyme called catalase from damage caused by chemotherapy drugs. The radiation, delivered at power levels about 1,000 times higher than typical cell phone exposure, showed no protective effect on the enzyme. This suggests that millimeter waves at these frequencies don't provide the cellular protection some researchers had hoped to find.

Brain & Nervous SystemNo Effects Found

Does head-only exposure to GSM-900 electromagnetic fields affect the performance of rats in spatial learning tasks?

Dubreuil D, Jay T, Edeline JM. · 2002

French researchers tested whether 45-minute exposures to 900-MHz GSM cell phone radiation affected spatial learning and memory in rats. They found no differences in performance on maze tasks between rats exposed to cell phone radiation (at levels of 1 and 3.5 W/kg SAR) and unexposed control rats. This contradicts some earlier studies that suggested electromagnetic fields could impair learning abilities.

Cancer & Tumors149 citations

Long-term exposure of E-mu-Pim1 transgenic mice to 898.4 MHz microwaves does not increase lymphoma incidence

Utteridge TD et al. · 2002

Researchers exposed cancer-prone mice to cell phone radiation (898.4 MHz) for up to 2 years at various intensities to see if it increased lymphoma rates. They found no significant increase in cancer incidence at any exposure level, even in mice genetically predisposed to develop lymphomas. This study contradicted an earlier 1997 study that found increased cancer risk from similar radiofrequency exposure.

Effects of exposure to low level radiofrequency fields on acetylcholine release in hippocampus of freely moving rats.

Testylier G, Tonduli L, Malabiau R, Debouzy JC · 2002

Researchers exposed freely moving rats to radiofrequency radiation at frequencies used by WiFi (2.45 GHz) and cell phones (800 MHz) to study effects on brain chemistry. They found that higher power exposures significantly reduced acetylcholine release in the hippocampus by 40-43%, a brain chemical crucial for memory and learning. The effects persisted for hours after exposure ended, suggesting that even brief RF exposure can disrupt normal brain function.

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