3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 1,014 studies (Rodent Studies)

Pulsed or continuous electromagnetic field induce p53/p21-mediated apoptotic signaling pathway in mouse spermatogenic cells in vitro and thus may affect male fertility.

Solek P et al. · 2017

Polish researchers exposed mouse sperm cells to electromagnetic fields at 2, 50, and 120 Hz frequencies for two hours. The exposure triggered cell death by damaging DNA and causing oxidative stress, potentially reducing healthy sperm and contributing to male fertility problems.

Preventing electromagnetic pulse irradiation damage on testis using selenium-rich Cordyceps fungi. A preclinical study in young male mice.

Miao X et al. · 2017

Researchers exposed young male mice to electromagnetic pulses (EMPs) for four weeks and found significant damage to sperm production and testicular health. The mice that received a protective antioxidant supplement (selenium-rich Cordyceps fungi) showed much less reproductive damage. This suggests that electromagnetic radiation can harm male fertility, but certain protective compounds might help reduce this damage.

Long-term exposure to 835 MHz RF-EMF induces hyperactivity, autophagy and demyelination in the cortical neurons of mice

Kim JH, Yu DH, Huh YH, Lee EH, Kim HG, Kim HR. · 2017

Researchers exposed mice to cell phone-level radiation (835 MHz) for 5 hours daily over 12 weeks and found significant brain changes. The radiation damaged the protective coating around brain cells (called myelin) and caused hyperactive behavior in the mice. This suggests that prolonged exposure to radiofrequency radiation at levels similar to heavy cell phone use may harm brain function and behavior.

Brain & Nervous SystemNo Effects Found

1950 MHz radiofrequency electromagnetic fields do not aggravate memory deficits in 5xFAD mice.

Son Y et al. · 2016

Researchers exposed mice genetically modified to develop Alzheimer's-like symptoms to cell phone radiation (1950 MHz) for 3 months to see if it would worsen their memory problems. The radiation exposure at 5 W/kg (about 5 times higher than typical phone use) did not make the mice's memory worse or increase the brain plaques associated with Alzheimer's disease. This suggests that cell phone radiation may not accelerate Alzheimer's progression, at least in this animal model.

Brain & Nervous SystemNo Effects Found

Cerebral radiofrequency exposures during adolescence: Impact on astrocytes and brain functions in healthy and pathologic rat models.

Petitdant N et al. · 2016

French researchers exposed adolescent rats to radiofrequency radiation at levels similar to cell phone use (1.5 and 6 W/kg SAR) for 45 minutes daily over a month to see if it affected brain development, anxiety, or memory. They found no differences between exposed and unexposed rats, even in animals made more vulnerable through induced brain inflammation. The study suggests adolescent brains may not be as sensitive to RF radiation as some have theorized.

DNA & Genetic DamageNo Effects Found

Analysis of gene expression in mouse brain regions after exposure to 1.9 GHz radiofrequency fields.

McNamee JP et al. · 2016

Canadian researchers exposed mice to 1.9 GHz radiofrequency radiation (similar to cell phone signals) for 4 hours daily over 5 days and examined gene activity in seven different brain regions. They found no consistent changes in gene expression at exposure levels of 0.2 or 1.4 W/kg, though they acknowledge their study may have missed very small changes below 1.5-fold. This suggests that short-term RF exposure at these levels doesn't significantly alter how genes function in the brain.

Disruption of the ovarian follicle reservoir of prepubertal rats following prenatal exposure to a continuous 900-MHz electromagnetic field.

Türedi S, Hancı H, Çolakoğlu S, Kaya H, Odacı E. · 2016

Researchers exposed pregnant rats to cell phone-frequency radiation (900 MHz) for one hour daily during late pregnancy and examined their female offspring's ovaries at 34 days old. The exposed offspring had significantly fewer healthy egg follicles and more damaged, dying follicles compared to unexposed controls. This suggests that EMF exposure during pregnancy may harm the developing reproductive system of female offspring.

Exposure to mobile phone electromagnetic field radiation, ringtone and vibration affects anxiety-like behaviour and oxidative stress biomarkers in albino wistar rats.

Shehu A, Mohammed A, Magaji RA, Muhammad MS · 2016

Nigerian researchers exposed rats to mobile phones for 4 weeks, testing different modes including silent, vibration, ringtone, or combined settings for 10 minutes daily. All exposed groups showed increased anxiety-like behavior compared to controls, while rats exposed to ringtones (with or without vibration) also showed reduced antioxidant enzyme activity in their brains. This suggests that mobile phone exposure affects both brain function and cellular stress responses, even when the phone isn't making noise.

Survival Assessment of Mouse Preimplantation Embryos After Exposure to Cell Phone Radiation

Safian F et al. · 2016

Iranian researchers exposed mouse embryos to cell phone radiation (900-1800 MHz) for 30 minutes daily during their first four days of development. While the embryos still developed normally to the blastocyst stage, they showed significantly higher cell death rates and reduced cell viability compared to unexposed embryos. This suggests that cell phone radiation may damage developing embryos even when overall development appears normal.

Maternal mobile phone exposure alters intrinsic electrophysiological properties of CA1 pyramidal neurons in rat offspring.

Razavinasab M, Moazzami K, Shabani M. · 2016

Researchers exposed pregnant rats to 900 MHz cell phone radiation for 6 hours daily and then tested their offspring's brain function. The exposed offspring showed reduced brain cell activity in the hippocampus (the brain's memory center) and performed worse on learning and memory tests. This suggests that cell phone exposure during pregnancy may impair brain development in offspring.

Metabolomic study of urinary polyamines in rat exposed to 915 MHz radiofrequency identification signal.

Paik MJ, Kim HS, Lee YS, Do Choi H, Pack JK, Kim N, Ahn YH · 2016

Researchers exposed rats to 915 MHz radiofrequency signals (like those from RFID tags) for 8 hours daily over 2 weeks and analyzed chemical changes in their urine. They found significant alterations in polyamines, which are molecules involved in cellular metabolism and growth. The RF-exposed rats showed a 54% increase in one specific polyamine compared to just 17% in control animals, suggesting the radiofrequency exposure disrupted normal cellular processes.

Long-term electromagnetic exposure of developing neuronal networks: A flexible experimental setup.

Oster S et al. · 2016

German researchers developed a sophisticated laboratory system to expose developing rat brain neurons to 900 MHz radiofrequency radiation (similar to cell phone frequencies) for weeks at a time. The study focused on creating reliable equipment to test whether wireless radiation affects developing brain tissue, using exposure levels of 362 milliwatts per kilogram. While the paper describes the experimental setup in detail, it doesn't report specific biological effects, serving instead as a foundation for future research on how RF radiation might impact the developing nervous system.

Effects of prenatal exposure to a 900 MHz electromagnetic field on 60-day-old rat testis and epididymal sperm quality.

Odacı E et al. · 2016

Researchers exposed pregnant rats to 900 MHz radiofrequency radiation (the same frequency used by many cell phones) for one hour daily during pregnancy, then examined the reproductive health of their male offspring at 60 days old. The exposed animals showed significantly reduced sperm quality, including lower sperm motility and vitality, along with increased DNA damage and cell death in their testes. This study suggests that EMF exposure during critical developmental periods may have lasting effects on male fertility.

Effects of Long Term Exposure of 900-1800 MHz Radiation Emitted from 2G Mobile Phone on Mice Hippocampus- A Histomorphometric Study.

Mugunthan N et al. · 2016

Researchers exposed mice to 2G mobile phone radiation (900-1800 MHz) for 48 minutes daily over six months and examined their brain tissue under a microscope. They found that the radiation caused significant changes in the hippocampus (the brain's memory center), including reduced numbers of neurons in key areas and smaller cell nuclei throughout the region. These cellular changes suggest that chronic mobile phone radiation exposure may damage the brain structures responsible for learning and memory.

Evidence of cellular stress and caspase-3 resulting from a combined two-frequency signal in the cerebrum and cerebellum of sprague-dawley rats.

López-Furelos A et al. · 2016

Spanish researchers exposed rats to cell phone frequencies (900 MHz and 2450 MHz) for 1-2 hours and found significant cellular stress in brain tissue 24 hours later. The study measured heat shock proteins (stress markers) and caspase-3 (a protein involved in cell death) in different brain regions. Surprisingly, when rats were exposed to both frequencies together, the effects weren't simply additive, suggesting that multiple EMF signals interact with brain tissue through complex mechanisms we don't fully understand.

Effects of long-term pre- and post-natal exposure to 2.45 GHz wireless devices on developing male rat kidney.

Kuybulu AE et al. · 2016

Researchers exposed pregnant rats and their offspring to 2.45 GHz wireless radiation (the same frequency used by WiFi and microwaves) and found significant kidney damage in the young rats. The exposed animals showed increased oxidative stress (cellular damage from harmful molecules), reduced antioxidant defenses, and visible tissue damage in their kidneys. This suggests that EMF exposure during pregnancy and early development may harm kidney function in developing organisms.

Effects of radiofrequency field exposure on glutamate-induced oxidative stress in mouse hippocampal HT22 cells.

Kim JY, Kim HJ, Kim N, Kwon JH, Park MJ. · 2016

Researchers exposed mouse brain cells to radiofrequency radiation while also treating them with glutamate, a brain chemical that becomes toxic in Alzheimer's disease. While RF exposure alone had minimal effects, it significantly amplified the damage when combined with glutamate, increasing cell death and harmful oxidative stress. This suggests that RF radiation may worsen brain cell vulnerability in conditions like Alzheimer's disease.

The effect of prenatal exposure to 1800 MHz electromagnetic field on calcineurin and bone development in rats.

Erkut A et al. · 2016

Researchers exposed pregnant rats to cell phone radiation (1800 MHz frequency) for varying durations during pregnancy and examined bone development in their offspring. They found that longer daily exposure periods caused significant damage to developing bones and muscles, with the worst effects occurring after 24 hours of daily exposure. The study demonstrates that wireless radiation during pregnancy can interfere with normal skeletal development in developing babies.

Neuroprotective effects of melatonin and omega-3 on hippocampal cells prenatally exposed to 900 MHz electromagnetic fields.

Erdem Koç G et al. · 2016

Turkish researchers exposed pregnant rats to cell phone radiation (900 MHz) for one hour daily throughout pregnancy, then examined brain development in their male offspring. They found that prenatal radiation exposure significantly reduced the number of pyramidal neurons in the hippocampus (a brain region critical for memory and learning). However, when pregnant rats received protective supplements like melatonin or omega-3 fatty acids alongside the radiation exposure, their offspring's brain development remained normal.

Effects of Electromagnetic Radiation from Smartphones on Learning Ability and Hippocampal Progenitor Cell Proliferation in Mice.

Choi Y-J, Choi Y-S. · 2016

Researchers exposed mice to smartphone electromagnetic radiation for 9-11 weeks and tested their learning ability and brain cell development. While the radiation didn't affect memory or cell growth, it did activate astrocytes (brain support cells) and caused hyperactivity-like behavior that persisted weeks after exposure ended. This suggests smartphone EMF can trigger lasting changes in brain function even without obvious cognitive impairment.

Radiofrequency radiation (900 MHz)-induced DNA damage and cell cycle arrest in testicular germ cells in swiss albino mice.

Pandey N, Giri S, Das S, Upadhaya P. · 2016

Researchers exposed male mice to 900 MHz radiofrequency radiation (similar to cell phone frequencies) for 4-8 hours daily for 35 days to study effects on sperm production. The radiation caused DNA damage in sperm-producing cells and disrupted the normal development process, resulting in significantly reduced sperm counts. While some recovery occurred after radiation exposure ended, the study demonstrates that RF radiation can impair male fertility through cellular damage.

Neuroprotective effects of lotus seedpod procyanidins on extremely low frequency electromagnetic field-induced neurotoxicity in primary cultured hippocampal neurons.

Yin C, Luo X, Duan Y, Duan W, Zhang H, He Y, Sun G, Sun X. · 2016

Researchers exposed rat brain cells (hippocampal neurons) to extremely low frequency electromagnetic fields and found significant damage including cell death, DNA damage, and disrupted cellular function. However, when they treated the cells with natural compounds called procyanidins from lotus seeds, these protective compounds prevented most of the EMF-induced damage. The study reveals that EMF exposure can harm brain cells through oxidative stress and cellular dysfunction, but also suggests that certain natural antioxidants might offer protection.

Levodopa enhances immobility induced by spinal cord electromagnetic stimulation in rats.

Sales PM, de Andrade LM, Pitcher MR, Rola FH, Gondim FA. · 2016

Researchers applied electromagnetic stimulation to the spinal cord area of rats and measured how it affected their movement and behavior. They found that electromagnetic exposure reduced walking activity and increased immobility, and this effect became more pronounced when rats were pre-treated with levodopa (a Parkinson's drug). The study suggests that electromagnetic fields can influence the nervous system's control of movement through dopamine pathways in the brain.

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