Tong J, Chen S, Liu XM, Hao DM. · 2013
Chinese researchers exposed rats to 900 MHz cell phone radiation and measured brain activity in the hippocampus, which controls learning and memory. The radiation disrupted normal neuron firing patterns and increased abnormal brain cell activity, potentially impairing cognitive function.
Gurbuz N, Sirav B, Colbay M, Yetkin I, Seyhan N. · 2013
Researchers exposed male Wistar albino rats to 1800 MHz or 2100 MHz radiofrequency radiation for 30 min per day, 6 days per week, for either a month or two months. They measured micronucleus frequency in exfoliated bladder cells as an indicator of genotoxic damage. No significant differences in micronucleus frequency were found between any exposed group and its corresponding control group, nor between the two 2100 MHz exposure durations.
Unknown authors · 2013
Researchers assessed potential organ damage using histopathological study. Exposed rats showed significant differences in Olive moment and percent DNA in blood compared to controls. Hyperchromasia was observed in ovaries, and reduced germ cells with cell disorganization were seen in testes with increasing SARs.
Behari J, Nirala JP. · 2013
A SAR measurement system was developed for a brain phantom in a Perspex box. The phantom box volume matched a small rat and was illuminated by a 3G mobile phone at 1718.5 MHz. A moving platform changed the phone's angular position at 2 degrees per minute up to 20 degrees while induced fields were measured. SAR values computed from induced fields were higher than those from induced field measurements alone and varied with angular position, but remained well below human safety criteria. SAR was also measured by temperature rise and compared with the induced-field results, and measurements were repeated in a 10 g phantom in a cubical box for safety criteria comparison.
El Gohary MI, Salama AA, El Saeid AA, El Sayed TM, Kotb HS. · 2013
Researchers studied how caffeine and extremely low-frequency magnetic field (ELF-MF) exposure affected brain electrical activity in rats over 15 days. Caffeine given at 10 mg/kg caused a reduction in the mean power amplitude of EEG signals across most frequency bands, especially the alpha band (8–12 Hz), and this effect was more evident in motor cortex than in visual cortex. Exposure to ELF-MF at 0.2 mT enhanced mean power amplitude in most EEG frequency bands, with the effect more pronounced in the right hemisphere than the left. When caffeine was given alongside ELF-MF exposure, a large increase in alpha-band amplitude appeared after 5 days at all recording sites.
El Gohary MI, Salama AA, El Saeid AA, El Sayed TM, Kotb HS. · 2013
Researchers exposed rats to extremely low frequency magnetic fields (the type emitted by power lines and appliances) for 15 days and found these fields significantly altered brain wave patterns, particularly enhancing activity in the right hemisphere. When caffeine was given alongside the magnetic field exposure, it appeared to partially counteract some of the brain changes, especially in areas controlling movement.
Gao X, Luo R, Ma B, Wang H, Liu T, Zhang J, Lian Z, Cui X. · 2013
Researchers exposed pregnant rats to 900MHz cell phone radiation for three hours daily throughout pregnancy and found significant brain damage in both mothers and offspring, including swollen brain cells and reduced antioxidant defenses. However, when rats were given vitamin E supplements during pregnancy, the protective antioxidant largely prevented this brain damage. This suggests that EMF exposure during pregnancy can harm developing brains, but certain nutrients may offer protection.
Unknown authors · 2013
Researchers exposed newly eclosed Drosophila melanogaster to a 50-Hz alternating magnetic field at 1, 11, and 21 G continuously for the first 5 days of adult life. The magnetic field decreased reproductive capacity by up to 4.3%, with the effect increasing at higher field intensities. The decline in reproductive capacity was attributed to severe DNA fragmentation and cell death in reproductive cells, detected by TUNEL assay during early and mid-oogenesis. The increase in DNA damage was more significant than the corresponding decrease in reproductive capacity (up to ~7.5%).
Yang L, Hao D, Wu S, Zhong R, Zeng Y. · 2013
The study numerically evaluated specific absorption rate and temperature rise in SD rat heads exposed to 900 MHz EMF. The digital anatomical model of a SD rat was reconstructed from MRI images and the finite difference time domain method was applied to assess SAR and temperature rise. Whole-body average SAR and localized SAR averaged over 1, 0.5 and 0.05 g mass for different organs and tissues were reported.
Banaceur S, Banasr S, Sakly M, Abdelmelek H · 2013
Researchers studied the effects of 2.4 GHz radiofrequency signals on wildtype mice and triple transgenic mice bred to develop Alzheimer's-like cognitive impairment. Mice were exposed two hours per day during one month at a Specific Absorption Rate of 1.60 W/kg. The researchers reported that radiofrequency exposure improved cognitive behavior in the 3xTg-AD mice.
Baş O et al. · 2013
Researchers exposed pregnant rats to a 900 MHz electromagnetic field on days 13 through 21 of pregnancy, then examined the brains of their female pups on postnatal day 32. Exposure during those prenatal days led to a significant decrease in the number of pyramidal cells in the cornu ammonis of the female rat pups (P<0.05). Histopathological examination also revealed picnotic cells in the cornu ammonis of the exposed female rat pups.
Deshmukh PS et al. · 2013
Deshmukh PS et al. · 2013
The study investigated possible DNA-damaging effects of low-level microwave radiation in the brains of male Fischer rats. Rats were exposed for 30 days at three frequencies: 900, 1800, and 2450 MHz, at specific absorption rates on the order of 10−4 W/kg. DNA damage in brain tissue was assessed using alkaline comet assay after the exposure period. The researchers concluded that low SAR microwave radiation at these frequencies may induce DNA strand breaks in brain tissue.
Haghani M, Shabani M, Moazzami K · 2013
Researchers exposed pregnant Wistar rats to 900-MHz pulse-EMF irradiation for 6 hours per day throughout gestation, then evaluated ten offspring per group. Behavioral tests did not reveal any abnormalities in the exposed offspring. Whole-cell patch clamp recordings revealed decreased neuronal excitability of Purkinje cells, with changes in afterhyperpolarization amplitude, spike frequency, half width, and first spike latency.
Lv B, Chen Z, Wu T, Shao Q, Yan D, Ma L, Lu K, Xie Y. · 2013
Eighteen subjects participated in a double-blind, crossover, randomized and counterbalanced experiment including real and sham exposure sessions. Resting-state fMRI signals were collected before and after exposure, with the radiation source placed close to the right ear. After real exposure, decreased ALFF values were found in the left superior temporal gyrus, left middle temporal gyrus, right superior temporal gyrus, right medial frontal gyrus, and right paracentral lobule.
Odacı E et al. · 2013
Researchers exposed pregnant rats to 900 MHz electromagnetic fields for one hour daily between days 13 and 21 of pregnancy, then assessed the female pups' spinal cord tissue and motor behavior. The rotarod test showed a significant increase in motor functions in the EMF group pups (p=0.037), while the open field test found no difference between groups. Pathological changes were observed in the spinal cords of the EMF group pups, and the researchers suggested these changes may have led to the increase in motor activity.
Bai WF, Xu WC, Feng Y, Huang H, Li XP, Deng CY, Zhang MS. · 2013
Researchers divided rat bone marrow stromal cells into three groups: one treated with electromagnetic fields, one induced without fields, and a control group. The cells in the EMF group expressed neuron-specific markers and genes, formed synaptic junctions, and pulsed excitatory postsynaptic currents. The researchers suggested that EMF appears to be a promising clinical option for stem cell transplantation therapies to combat central nervous system diseases.
Balassa T et al. · 2013
Researchers exposed rats to extremely low-frequency magnetic fields (0.5 and 3 mT, 50 Hz) during two critical periods of brain development: in utero during the second gestation week, or as newborns for 7 days starting 3 days after birth. Basic excitability of hippocampal slices was increased by both the fetal 0.5 mT and the newborn 3 mT treatments. Fetal exposure significantly inhibited paired-pulse depression and significantly decreased the efficacy of long-term potentiation induction in the neocortex, but not in the hippocampus. Neonatal treatment had no significant effect on plasticity phenomena.
Calabrò E et al. · 2013
Researchers used SH-SY5Y neuroblastoma cells as an experimental model to study the effects of a 50 Hz electromagnetic field in the range from 50 µT to 1.4 mT. Fourier transform infrared spectroscopy analysis showed a reduction in intensity of the amide A band and a slight increase of vibration bands corresponding to methylene groups. Exposure to a 50 Hz electromagnetic field higher than 0.8 mT was associated with a significant reduction of cell viability and reduced mitochondrial transmembrane potential.
Deng Y, Zhang Y, Jia S, Liu J, Liu Y, Xu W, Liu L. · 2013
Researchers divided sixty male SPF Kunming mice into four groups: a control group, an ELF-MF group exposed at 2 mT for 4 hours per day, a group given aluminum at 200 mg per kg, and a combined ELF-MF plus aluminum group. After 8 weeks of treatment, all three exposure groups showed learning memory impairment, with prolonged escaping latency to the platform and a reduced percentage of time in the platform quadrant in the Morris water maze task. All three exposed groups showed a statistically significant decrease in superoxide dismutase activity and an increase in malondialdehyde levels. The combined ELF-MF plus aluminum treatment induced no more damage than ELF-MF and aluminum did separately.
Duan Y, Wang Z, Zhang H, He Y, Lu R, Zhang R, Sun G, Sun X. · 2013
Researchers investigated whether lotus seedpod procyanidins (LSPCs) given by oral gavage could protect mice from cognitive deficits and oxidative damage caused by extremely low frequency electromagnetic field (ELF-EMF) exposure at 50 Hz and 8 mT for 28 days. A water maze test indicated that learning and memory abilities of the ELF-EMF group deteriorated significantly compared with the control group, but the ELF-EMF + LSPCs90 group had remarkably improved learning and memory abilities compared with the ELF-EMF group. ELF-EMF exposure was associated with significant increases in oxidative stress markers and decreases in antioxidant enzyme activities.
Manjhi J, Kumar S, Behari J, Mathur R. · 2013
Researchers studied whether extremely low frequency (ELF) magnetic field exposure could reduce osteoporosis caused by spinal cord injury in rats. Adult male Wistar rats (n = 24) were equally divided into sham, SCI, and SCI+MF groups. Starting one day after injury, the exposed group received ELF magnetic field at 17.96 micro-Tesla and 50 Hz for two hours per day over eight weeks. Bone mineral content, bone mineral density, and biochemical markers were significantly lower in spinal cord injury rats compared with the sham group, and these decreases were attenuated in the magnetic field-treated group, except for carbon content.
Park JE, Seo YK, Yoon HH, Kim CW, Park JK, Jeon S · 2013
Researchers treated human bone marrow derived mesenchymal stem cells (hBM-MSCs) with ELF-EMF at 50 Hz and 1 mT and measured neural marker expression and cell signaling. The expression of neural markers NF-L, MAP2, and NeuroD1 increased at 6 days, while phosphorylation of Akt and CREB, but not ERK, increased at 90 min. The researchers suggest that EMF induces neural differentiation through activation of EGFR signaling and mild generation of reactive oxygen species (ROS).
Atasoy HI, Gunal MY, Atasoy P, Elgun S, Bugdayci G · 2013
Researchers exposed male rats to radiofrequency radiation from Wi-Fi devices operating at 2.437 GHz for 24 hours a day for 20 weeks, then examined their testes. The exposed rats showed significant increases in markers indicating DNA damage in the testes compared to controls. Catalase and glutathione peroxidase activity were decreased in the exposed group, which the researchers suggested may have been due to radiofrequency effects on enzyme activity. The researchers said these findings raise questions about the safety of radiofrequency exposure from Wi-Fi Internet access devices for growing organisms of reproductive age, with a potential effect on both fertility and the integrity of germ cells.
Hancı H et al. · 2013
Researchers exposed pregnant rats to 900-MHz EMF during days 13–21 of pregnancy and examined the testicles of their offspring at postnatal day 21. The offspring of exposed mothers showed irregularities in seminiferous tubule basal membrane and epithelium, immature germ cells in the lumen, and a decreased diameter in seminiferous tubules and thickness of epithelium. Apoptotic index, lipid peroxidation, and DNA oxidation were higher in the offspring of exposed mothers than in controls.