3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 1,644 studies in Brain & Nervous System

Chronic exposure to an extremely low-frequency magnetic field induces depression-like behavior and corticosterone secretion without enhancement of the hypothalamic-pituitary-adrenal axis in mice.

Kitaoka K, Kitamura M, Aoi S, Shimizu N, Yoshizaki K. · 2013

Researchers exposed mice to extremely low-frequency magnetic fields (ELF-MF) at 3 milliTesla for 200 hours to study effects on mood and stress hormones. The exposed mice showed depression-like behaviors, increased anxiety, and elevated levels of corticosterone (a stress hormone), suggesting that chronic magnetic field exposure may affect mental health and stress response systems.

Influence of Magnetic Field on Brain Activity During Administration of Caffeine.

El Gohary MI, Salama AA, El Saeid AA, El Sayed TM, Kotb HS. · 2013

Researchers exposed rats to extremely low frequency magnetic fields (the type emitted by power lines and appliances) for 15 days and found these fields significantly altered brain wave patterns, particularly enhancing activity in the right hemisphere. When caffeine was given alongside the magnetic field exposure, it appeared to partially counteract some of the brain changes, especially in areas controlling movement.

The preventive effect of lotus seedpod procyanidins on cognitive impairment and oxidative damage induced by extremely low frequency electromagnetic field exposure.

Duan Y, Wang Z, Zhang H, He Y, Lu R, Zhang R, Sun G, Sun X. · 2013

Researchers exposed mice to 50 Hz magnetic fields (the type from power lines) for 28 days and found it damaged their learning, memory, and brain cells through oxidative stress. When mice were given lotus seedpod antioxidants during exposure, these harmful effects were largely prevented. This suggests that extremely low frequency EMF exposure can cause measurable brain damage, but antioxidants may offer some protection.

Effects of aluminum and extremely low frequency electromagnetic radiation on oxidative stress and memory in brain of mice.

Deng Y, Zhang Y, Jia S, Liu J, Liu Y, Xu W, Liu L. · 2013

Researchers exposed mice to extremely low frequency magnetic fields (ELF-MF) at 2 milliTesla for 4 hours daily over 8 weeks, testing both memory and brain chemistry. The magnetic field exposure caused significant memory impairment in maze tests and increased oxidative stress markers in the brain, similar to the damage caused by aluminum toxicity. These findings suggest that prolonged exposure to strong magnetic fields can harm brain function through oxidative damage.

50 Hz Electromagnetic Field Produced Changes in FTIR Spectroscopy Associated with Mitochondrial Transmembrane Potential Reduction in Neuronal-Like SH-SY5Y Cells.

Calabrò E et al. · 2013

Italian researchers exposed human brain cells to 50 Hz magnetic fields (European power frequency) and found exposures above 0.8 milliTesla damaged cellular energy systems and altered protein structures. This demonstrates measurable biological harm from power-frequency magnetic fields at levels found in some occupational environments.

Neuropathology and behavioral impairments in Wistar rats with a 6-OHDA lesion in the substantia nigra compacta and exposure to a static magnetic field.

Bertolino G, Dutra Souza HC, de Araujo JE. · 2013

Researchers exposed rats with chemically-induced brain damage (mimicking Parkinson's disease) to static magnetic fields of 3200 gauss for 14 days. The magnetic field exposure helped preserve neurons in the brain region affected by Parkinson's and improved motor function compared to rats that didn't receive magnetic treatment. This suggests static magnetic fields might have therapeutic potential for protecting brain cells from neurodegenerative damage.

Changes in synaptic efficacy in rat brain slices following extremely low-frequency magnetic field exposure at embryonic and early postnatal age.

Balassa T et al. · 2013

Researchers exposed developing rats to 50 Hz magnetic fields (the same frequency as power lines) during critical brain development periods and found lasting changes in brain function. The exposed animals showed altered electrical activity in brain regions responsible for learning and memory, with some changes persisting weeks after exposure ended. This suggests that magnetic field exposure during early development may affect how the brain processes information later in life.

Fifty-Hertz electromagnetic fields facilitate the induction of rat bone mesenchymal stromal cells to differentiate into functional neurons.

Bai WF, Xu WC, Feng Y, Huang H, Li XP, Deng CY, Zhang MS. · 2013

Researchers exposed rat bone marrow stem cells to 50 Hz electromagnetic fields (the same frequency as household electricity) for one hour daily over 12 days. The EMF exposure significantly enhanced the stem cells' ability to transform into functional brain neurons, complete with working synapses and electrical activity. This suggests that power frequency magnetic fields can directly influence cellular development and may have therapeutic applications for treating nervous system diseases.

Effect of low level microwave radiation exposure on cognitive function and oxidative stress in rats

Deshmukh PS et al. · 2013

Researchers exposed rats to extremely low-level 900 MHz microwave radiation (similar to cell phone frequencies) for 2 hours daily over 30 days. The exposed rats showed significant memory and learning problems, plus increased oxidative stress (cellular damage) in their blood. This matters because the radiation level was about 1,000 times lower than current safety limits, yet still caused measurable brain and cellular effects.

Effect of 900 MHz radıofrequency radıatıon on oxıdatıve stress in rat brain and serum

Bilgici B, Akar A, Avci B, Tuncel OK · 2013

Researchers exposed rats to 900 MHz radiofrequency radiation (the same frequency used by many cell phones) for one hour daily over three weeks at levels similar to what humans experience. They found significant increases in oxidative stress markers in the brain, indicating cellular damage from free radicals. Interestingly, rats given garlic powder showed protection against this brain damage, suggesting antioxidants may help counteract RF radiation effects.

Age-dependent effects of ELF-MF on oxidative stress in the brain of mongolian gerbils.

Selaković V, Rauš Balind S, Radenović L, Prolić Z, Janać B. · 2013

Scientists exposed gerbils to power line frequency magnetic fields for seven days. The exposure increased brain cell damage in all tested regions, with stronger effects in older animals and at higher field strengths. Younger brains recovered better after exposure ended, suggesting age affects vulnerability.

Electromagnetic fields induce neural differentiation of human bone marrow derived mesenchymal stem cells via ROS mediated EGFR activation.

Park JE, Seo YK, Yoon HH, Kim CW, Park JK, Jeon S · 2013

Researchers exposed human bone marrow stem cells to 50 Hz magnetic fields (the same frequency as power lines) at 1 milliTesla for several days. They found that this EMF exposure triggered the stem cells to transform into nerve cells by activating specific cellular pathways and generating reactive oxygen species (ROS). This suggests that power-frequency magnetic fields can directly influence how our stem cells develop and differentiate.

Effects of low intensity static magnetic field on FTIR spectra and ROS production in SH-SY5Y neuronal-like cells.

Calabrò E et al. · 2013

Italian researchers exposed human brain cells to a static magnetic field at 2.2 millitesla (below current safety limits) for 24 hours and found significant cellular damage. The magnetic field reduced the cells' energy production by 30%, increased harmful reactive oxygen species, and altered the structure of cellular proteins and fats. This demonstrates that even magnetic fields considered 'safe' by regulatory standards can disrupt normal brain cell function.

Do 100- and 500-μT ELF magnetic fields alter beta-amyloid protein, protein carbonyl and malondialdehyde in rat brains?

Akdag MZ, Dasdag S, Cakir DU, Yokus B, Kizil G, Kizil M. · 2013

Researchers exposed rats to magnetic fields at levels considered safe by current standards for 10 months. The exposure significantly increased two markers of brain cell damage and aging, suggesting that even "safe" magnetic field levels may cause harmful oxidative stress in brain tissue over time.

Changes of dendritic spine density and morphology in the superficial layers of the medial entorhinal cortex induced by extremely low-frequency magnetic field exposure.

Xiong J, He C, Li C, Tan G, Li J, Yu Z, Hu Z, Chen F. · 2013

Researchers exposed rats to power line-frequency magnetic fields for 14-28 days and found significant damage to brain cell connections in the entorhinal cortex, a memory center. The exposure destroyed dendritic spines that enable brain cells to communicate, potentially explaining EMF-related cognitive problems.

Effects of exposure to a 50 Hz sinusoidal magnetic field during the early adolescent period on spatial memory in mice.

Wang X et al. · 2013

Researchers exposed young adolescent mice to 50 Hz magnetic fields (the same frequency as power lines) for one hour daily during a critical brain development period. Surprisingly, the exposed mice showed improved spatial learning and memory compared to unexposed mice when tested in maze tasks. This unexpected finding suggests that magnetic field exposure during adolescence might enhance certain cognitive abilities, though the implications for human brain development remain unclear.

The influence of static magnetic field (50 mT) on development and motor behaviour of Tenebrio (Insecta, Coleoptera)

Todorović D et al. · 2013

Researchers exposed beetle pupae to a 50 milliTesla static magnetic field (about 1,000 times stronger than Earth's magnetic field) to study development and behavior. While the magnetic field didn't affect how long it took beetles to develop from pupae to adults, it did alter their movement patterns and activity levels once they became adults. This suggests that even non-radiofrequency magnetic fields can influence nervous system function in living organisms.

Age-Dependent Effects of ELF-MF on Oxidative Stress in the Brain of Mongolian Gerbils.

Selaković V, Rauš Balind S, Radenović L, Prolić Z, Janać B. · 2013

Researchers exposed young adult and middle-aged gerbils to 50 Hz magnetic fields at three different intensities for seven days, then measured oxidative stress markers in their brains. They found that magnetic field exposure increased oxidative stress in all brain regions tested, with stronger effects at higher field intensities and in older animals. The effects were still detectable three days after exposure ended, particularly in the middle-aged gerbils.

Response of Hippocampal Neurons and Glial Cells to Alternating Magnetic Field in Gerbils Submitted to Global Cerebral Ischemia.

Rauš S et al. · 2013

Researchers exposed gerbils to 50 Hz magnetic fields (the same frequency as power lines) for 7 days after inducing stroke-like brain damage. The magnetic field exposure actually reduced brain cell death in the hippocampus, the brain region most critical for memory formation. This suggests that certain magnetic field exposures might have protective effects on brain tissue after injury.

Effect of extremely low frequency magnetic field in prevention of spinal cord injury-induced osteoporosis.

Manjhi J, Kumar S, Behari J, Mathur R. · 2013

Researchers studied whether extremely low frequency magnetic fields could prevent bone loss in rats with spinal cord injuries. They exposed injured rats to 50 Hz magnetic fields (17.96 microTesla) for 2 hours daily over 8 weeks and found the treatment significantly prevented osteoporosis, maintaining bone density and mineral content compared to untreated injured rats. This suggests that specific magnetic field therapy might help preserve bone health after spinal cord injury.

Exposure to extremely low-frequency magnetic field restores spinal cord injury-induced tonic pain and its related neurotransmitter concentration in the brain

Kumar S et al. · 2013

Researchers exposed rats with spinal cord injuries to extremely low-frequency magnetic fields (50 Hz, similar to power line frequencies) for 2 hours daily over 8 weeks. The magnetic field exposure restored normal pain responses and corrected abnormal brain chemical levels that had developed after the spinal injury. This suggests that specific EMF exposures might have therapeutic potential for certain neurological conditions.

Chronic exposure to an extremely low‐frequency magnetic field induces depression‐like behavior and corticosterone secretion without enhancement of the hypothalamic–pituitary–adrenal axis in mice†

Kitaoka K, Kitamura M, Aoi S, Shimizu N, Yoshizaki K. · 2013

Researchers exposed mice to extremely low frequency magnetic fields (ELF-MF) at 3 milliTesla for 200 hours and measured their behavior and stress hormone levels. The exposed mice showed significantly more depression and anxiety-like behaviors, along with elevated levels of the stress hormone corticosterone. This suggests that chronic exposure to strong magnetic fields may affect mental health and stress response systems.

Exposure to extremely low-frequency electromagnetic fields modulates Na+ currents in rat cerebellar granule cells through increase of AA/PGE2 and EP receptor-mediated cAMP/PKA pathway.

He YL, Liu DD, Fang YJ, Zhan XQ, Yao JJ, Mei YA. · 2013

Chinese researchers exposed rat brain cells to power line-frequency electromagnetic fields for 10-60 minutes and found sodium channels increased activity by 30-125%. Since sodium channels control nerve signals, this suggests EMF exposure can directly alter how brain cells communicate with each other.

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