3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 1,453 studies in Cellular Effects

DNA & Genetic DamageNo Effects Found

Human Fibroblasts and 900 MHz Radiofrequency Radiation: Evaluation of DNA Damage after Exposure and Co-exposure to 3-Chloro-4-(dichloromethyl)-5-Hydroxy-2(5h)-furanone (MX).

Sannino A et al. · 2009

Researchers exposed human skin cells to 900 MHz radiofrequency radiation (the same frequency used by GSM cell phones) for 24 hours at power levels similar to phone use. They found no DNA damage from the RF radiation alone, and the radiation did not make cells more vulnerable to damage from a known cancer-causing chemical. This suggests that cell phone-level RF exposure may not directly break DNA strands in human cells.

DNA & Genetic DamageNo Effects Found

Cytogenetic effects of exposure to 2.3 GHz radiofrequency radiation on human lymphocytes in vitro.

Hansteen IL et al. · 2009

Norwegian researchers exposed human immune cells (lymphocytes) to 2.3 GHz radiofrequency radiation - similar to what cell phones emit - for an entire cell cycle to see if it would damage DNA or chromosomes. They found no statistically significant genetic damage compared to unexposed cells, even when they added a known DNA-damaging chemical to make cells more vulnerable. This suggests that RF radiation at levels used by mobile devices may not directly break chromosomes in immune cells under these laboratory conditions.

DNA & Genetic DamageNo Effects Found

Cytogenetic effects of 18.0 and 16.5 GHz microwave radiation on human lymphocytes in vitro.

Hansteen IL et al. · 2009

Norwegian researchers exposed human immune cells (lymphocytes) to high-frequency microwave radiation at levels similar to industrial applications for 53 hours to test for DNA damage. They found no statistically significant genetic damage from either continuous 18.0 GHz or pulsed 16.5 GHz radiation, though the pulsed exposure showed a non-significant trend toward increased genetic abnormalities that the researchers said needs further study.

Cellular EffectsNo Effects Found

Effects of exposure to DAMPS and GSM signals on ornithine decarboxylase (ODC) activity: I. L-929 mouse fibroblasts.

Billaudel B, Taxile M, Ruffie G, Veyret B, Lagroye I. · 2009

Researchers exposed mouse cells to cell phone signals (DAMPS and GSM) for one hour to see if it would increase activity of ornithine decarboxylase (ODC), an enzyme linked to cell growth and potentially cancer development. They found no significant changes in ODC activity at exposure levels of 2.5 and 6 W/kg, contradicting some earlier studies that reported increased enzyme activity. This suggests that under controlled temperature conditions, these specific cell phone signals may not trigger this particular cellular response.

Cellular EffectsNo Effects Found

Effects of exposure to DAMPS and GSM signals on Ornithine Decarboxylase (ODC) activity: II. SH-SY5Y human neuroblastoma cells.

Billaudel B et al. · 2009

Researchers exposed human brain tumor cells to cell phone radiation similar to DAMPS and GSM signals for up to 24 hours, then measured changes in an enzyme called ornithine decarboxylase (ODC) that's involved in cell growth. They found no changes in ODC activity regardless of the type of signal, exposure duration, or radiation intensity. This suggests that typical cell phone radiation levels don't affect this particular cellular process in brain cells.

DNA & Genetic DamageNo Effects Found

Human fibroblasts and 900 MHz radiofrequency radiation: evaluation of DNA damage after exposure and co-exposure to 3-Chloro-4-(dichloromethyl)-5-Hydroxy-2(5h)-furanone (MX).

Sannino A et al. · 2009

Researchers exposed human skin cells to 900 MHz radiofrequency radiation (similar to cell phone signals) for 24 hours at 1 W/kg to test for DNA damage. They found no genetic damage from the RF exposure alone, even when testing cells from people with Turner's syndrome who may be more sensitive. The radiation also didn't make cells more vulnerable to damage from a known water contaminant.

Brain & Nervous SystemNo Effects Found

Effects of 50 Hz electromagnetic fields on rat cortical synaptosomes.

Aldinucci C et al. · 2009

Italian researchers exposed rat brain nerve terminals (synaptosomes) to 50 Hz magnetic fields at 2 milliTesla for 2 hours and measured multiple indicators of cellular function including energy production, calcium levels, and oxidative stress markers. They found no changes in any of the measured parameters, indicating that this level of extremely low frequency magnetic field exposure did not affect normal nerve terminal function. This suggests that moderate-strength power frequency magnetic fields may not directly disrupt basic brain cell operations at the cellular level.

Oxidative StressNo Effects Found

Reactive oxygen species formation is not enhanced by exposure to UMTS 1950 MHz radiation and co-exposure to ferrous ions in Jurkat cells

Brescia F et al. · 2009

Researchers exposed human immune cells to 1950 MHz cell phone radiation (the frequency used by 3G networks) to see if it would trigger oxidative stress, a cellular damage process linked to aging and disease. They tested various exposure durations and power levels, both alone and combined with iron compounds known to cause oxidative stress. The study found no increase in harmful reactive oxygen species or cell death from the radiation exposure under any conditions tested.

Oxidative StressNo Effects Found

Antioxidants alleviate electric field-induced effects on lung tissue based on assays of heme oxygenase-1, protein carbonyl content, malondialdehyde, nitric oxide, and hydroxyproline.

Güler G, Türközer Z, Ozgur E, Seyhan N. · 2009

Researchers exposed lung tissue to extremely strong electric fields (12,000 volts per meter) for 8 hours daily over 7 days to test whether antioxidants could prevent damage. They found only minor increases in one marker of cellular damage (protein carbonyl), while other damage indicators remained unchanged. The study suggests that at these exposure levels, electric fields cause minimal lung tissue damage that antioxidants may help prevent.

Oxidative StressNo Effects Found

Protein oxidation under extremely low frequency electric field in guinea pigs. Effect of N-acetyl-L-cysteine treatment.

Güler G, Türközer Z, Ozgur E, Tomruk A, Seyhan N, Karasu C · 2009

Researchers exposed guinea pigs to power line frequency electric fields (12 kV/m for 8 hours daily over 7 days) to study protein damage and whether the antioxidant N-acetyl-L-cysteine could protect against it. The study found no significant protein damage from the electric field exposure alone, though it did reduce a protein synthesis marker in the liver. The antioxidant treatment showed some effects on protein markers, suggesting it may have biological activity in this context.

Brain & Nervous SystemNo Effects Found

Effects of 50 Hz electromagnetic fields on rat cortical synaptosomes

Aldinucci C et al. · 2009

Italian researchers exposed rat brain nerve terminals (synaptosomes) to 50 Hz magnetic fields at 2 milliTesla for 2 hours to study effects on basic cellular functions. They found no changes in energy production, calcium levels, membrane function, or oxidative stress markers. This suggests that power-frequency magnetic fields at this intensity don't disrupt fundamental brain cell processes.

Brain & Nervous SystemNo Effects Found

Expression of the water channel protein, aquaporin-4, in mouse brains exposed to mobile telephone radiofrequency fields

Finnie JW, Blumbergs PC, Cai Z, Manavis J · 2009

Researchers exposed mice to cell phone radiation at 900 MHz for either one hour or two years to see if it would increase a brain protein called aquaporin-4, which rises when the blood-brain barrier becomes leaky. They found no increase in this protein after either short or long-term exposure, suggesting that cell phone radiation at this level doesn't make the blood-brain barrier more permeable.

Dose related shifts in the developmental progress of chick embryos exposed to mobile phone induced electromagnetic fields.

Zareen N, Khan MY, Minhas LA. · 2009

Researchers exposed developing chick embryos to mobile phone electromagnetic fields at different intensities to study effects on survival and development. They found that EMF exposure significantly reduced embryo survival rates, while the developmental effects varied dramatically by dose - lower exposures caused growth delays, while higher exposures actually accelerated growth. This suggests that mobile phone radiation affects developing organisms in complex, dose-dependent ways that could have implications for human reproductive health.

Derangement of chick embryo retinal differentiation caused by radiofrequency electromagnetic fields.

Zareen N, Khan MY, Minhas LA. · 2009

Researchers exposed developing chicken embryos to mobile phone radiation during critical stages of eye development and found significant disruptions in retinal growth and pigmentation. Embryos exposed for 10 days showed stunted retinal growth, while those exposed for 15 days showed excessive growth with intense pigmentation changes. This suggests that radiofrequency radiation from mobile phones can interfere with normal eye development in developing embryos.

Mobile and cordless telephones, serum transthyretin and the blood-cerebrospinal fluid barrier: a cross-sectional study

Soderqvist F, Carlberg M, Hardell L · 2009

Swedish researchers examined whether long-term mobile and cordless phone use affects the blood-cerebrospinal fluid barrier by measuring transthyretin, a protein that helps protect the brain. They found that men who used phones longer had higher transthyretin levels, while women showed elevated levels when blood was drawn soon after phone calls. These changes suggest that radiofrequency radiation may alter the brain's protective barriers.

Effects of mobile phone radiofrequency on the structure and function of the normal human hemoglobin.

Mousavy SJ et al. · 2009

Researchers exposed human hemoglobin (the protein in red blood cells that carries oxygen) to cell phone radiofrequency radiation at 910MHz and 940MHz frequencies. They found that the radiation altered hemoglobin's ability to carry oxygen and changed its molecular structure, with greater effects at higher radiation intensities and longer exposure times. This suggests that cell phone radiation could potentially interfere with your blood's fundamental ability to transport oxygen throughout your body.

Increased nitric oxide synthase activity is essential for electromagnetic-pulse-induced blood-retinal barrier breakdown in vivo.

Lu L, Xu H, Wang X, Guo G. · 2009

Researchers exposed rats to electromagnetic pulses (EMPs) and found that this radiation broke down the blood-retinal barrier, a protective membrane that shields the eye's retina from harmful substances in the bloodstream. The breakdown occurred through increased production of nitric oxide, a chemical that damages the barrier's protective proteins. This suggests that electromagnetic radiation can compromise critical protective barriers in the eye, potentially leading to vision problems.

The action of pulse-modulated GSM radiation increases regional changes in brain activity and c-Fos expression in cortical and subcortical areas in a rat model of picrotoxin-induced seizure proneness.

López-Martín E et al. · 2009

Researchers exposed rats to GSM cell phone radiation (the type used in mobile phones) and found it specifically amplified brain activity in animals already prone to seizures. The pulse-modulated radiation from GSM signals affected different brain regions than continuous radiation, particularly areas involved in memory and emotion processing. This suggests that the specific pulsing pattern of cell phone signals may have unique effects on brain function, especially in vulnerable individuals.

Immune System128 citations

Disturbance of the immune system by electromagnetic fields-A potentially underlying cause for cellular damage and tissue repair reduction which could lead to disease and impairment.

Johansson O. · 2009

This comprehensive review by Swedish researcher Olle Johansson examined dozens of studies on how electromagnetic fields affect the immune system. The research shows that EMF exposure disrupts immune function by triggering allergic and inflammatory responses while impairing the body's ability to repair tissue damage. These immune disruptions occur at EMF levels well below current safety limits and may increase disease risk, including cancer.

The effects of microwave emitted by cellular phones on ovarian follicles in rats.

Gul A, Celebi H, Uğraş S. · 2009

Researchers exposed pregnant rats to cell phone radiation throughout pregnancy and found their female offspring had significantly fewer ovarian follicles (egg-containing structures) compared to unexposed controls. The study suggests that prenatal exposure to cell phone microwaves may harm developing reproductive organs. This raises important questions about potential fertility impacts from wireless device exposure during pregnancy.

900-MHz microwave radiation enhances gamma-ray adverse effects on SHG44 cells.

Cao Y, Zhang W, Lu MX, Xu Q, Meng QQ, Nie JH, Tong J. · 2009

Researchers exposed brain cancer cells to 900-MHz microwave radiation (the same frequency used by many cell phones) before treating them with gamma rays. They found that the microwave exposure made the cells more vulnerable to radiation damage, increasing cell death and creating more harmful reactive oxygen species. This suggests that EMF exposure might amplify the harmful effects of other types of radiation.

Microwaves from UMTS/GSM mobile phones induce long-lasting inhibition of 53BP1/gamma-H2AX DNA repair foci in human lymphocytes.

Belyaev IY, Markovà E, Hillert L, Malmgren LO, Persson BR. · 2009

Researchers exposed human white blood cells to microwave radiation from GSM and UMTS mobile phones and found that the radiation interfered with the cells' ability to repair DNA damage. The interference lasted up to 72 hours after exposure - longer than the cellular stress response from heat shock. UMTS signals (used in 3G phones) appeared to cause more biological disruption than older GSM signals, suggesting newer phone technologies may pose greater health risks.

Effects of computer monitor-emitted radiation on oxidant/antioxidant balance in cornea and lens from rats.

Balci M, Namuslu M, Devrim E, Durak I. · 2009

Researchers exposed rats to computer monitor radiation for three weeks and measured damage markers in their eye tissues. They found increased oxidative stress (cellular damage from free radicals) in both the cornea and lens of the eye. When rats were given vitamin C alongside the radiation exposure, it helped protect the lens tissue from damage.

Effect of electromagnetic field induced by radio frequency waves at 900 to 1800 MHz on bone mineral density of iliac bone wings.

Atay T et al. · 2009

Turkish researchers measured bone density in the hip area of 150 men who regularly carried cell phones for an average of 6.2 years and 14.7 hours daily. They found slightly lower bone density on the side where phones were carried compared to the unexposed side, though the difference wasn't statistically significant. The findings suggest that long-term phone carrying might affect bone health in ways that could matter for medical procedures requiring bone grafts.

Aluminum, calcium ion and radiofrequency synergism in acceleration of lymphomagenesis.

Anghileri LJ, Mayayo E, Domingo JL. · 2009

Researchers studied how aluminum combined with radiofrequency radiation affects cancer development in mice with lymphoma. They found that this combination accelerated cancer progression and death, causing rapid growth of lymphoid tissue in the spleen and liver. The effect was strongest when aluminum could easily release ions in the body, suggesting that aluminum and RF radiation work together to disrupt normal cellular processes.

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