8,700 Studies Reviewed. 87.0% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 8,700 peer-reviewed studies on electromagnetic field health effects from 4 research libraries.

Filter Studies

Clear all filters

Showing 522 studies in Immune System

Induction of Poly(ADP-ribose) Polymerase in Mouse Bone Marrow Stromal Cells Exposed to 900 MHz Radiofrequency Fields: Preliminary Observations.

He Q, Sun Y, Zong L, Tong J, Cao Y. · 2016

Researchers exposed mouse bone marrow cells to cell phone-level radiation for three hours daily over five days. The cells showed significant increases in PARP-1, a protein that repairs DNA damage, suggesting the radiation triggered cellular stress requiring DNA repair mechanisms.

Effect of Radiofrequency Radiation on Human Hematopoietic Stem Cells.

Gläser K et al. · 2016

German researchers exposed human blood stem cells (the cells that create all blood cells in your body) to cell phone radiation at three different frequencies for up to 66 hours. They tested multiple biological endpoints including DNA damage, cell death, and oxidative stress. Surprisingly, they found that GSM radiation actually caused a small decrease in DNA damage compared to unexposed cells, while showing no other significant effects.

Electromagnetic pulse activated brain microglia via the p38 MAPK pathway

Yang LL et al. · 2016

Researchers exposed rats to electromagnetic pulses (EMP) at extremely high levels and found that these exposures activated microglia, the brain's immune cells, causing inflammation. The study identified that this brain immune response happened through a specific cellular pathway called p38 MAPK, and the effects were measurable within hours of exposure. This research helps explain one biological mechanism by which electromagnetic fields might affect brain function.

Extremely low frequency magnetic fields regulate differentiation of regulatory T cells: Potential role for ROS-mediated inhibition on AKT

Tang R, Xu Y, Ma F, Ren J, Shen S, Du Y, Hou Y, Wang T · 2016

Researchers exposed mice with lung cancer to extremely low frequency magnetic fields (7.5 Hz, 0.4 Tesla) for 2 hours daily over 27 days and found the treatment significantly reduced tumor spread in the lungs. The magnetic fields worked by altering immune cell behavior - specifically reducing regulatory T cells (immune cells that normally suppress anti-tumor responses) and increasing cellular stress molecules called reactive oxygen species. This suggests that certain magnetic field exposures might enhance the body's natural ability to fight cancer by modifying immune system function.

50 Hz electromagnetic field exposure promotes proliferation and cytokine production of bone marrow mesenchymal stem cells

Unknown authors · 2015

Researchers exposed bone marrow stem cells from rats and mice to 50 Hz electromagnetic fields (the same frequency as power lines) for several days. The EMF exposure increased stem cell growth and boosted production of immune-signaling molecules. The study found these EMF-stimulated stem cells also enhanced the growth and movement of immune cells when their secretions were tested.

D'Angelo C et al, (January 2015) Experimental model for ELF-EMF exposure: Concern for human health, Saudi J Biol Sci. 2015 Jan;22(1):75-84. doi: 10.1016/j.sjbs.2014.07.006

Unknown authors · 2015

Italian researchers exposed four different types of human cells to 50 Hz electromagnetic fields (the same frequency as power lines) at 1 milliTesla strength. They found that this exposure changed the production of MCP-1, a protein involved in immune response and inflammation, but the effects varied depending on the cell type. This suggests that power-frequency EMFs can trigger biological responses in human cells, though more research is needed to understand the health implications.

Influence of extremely low frequency electromagnetic fields on growth performance, innate immune response, biochemical parameters and disease resistance in rainbow trout, Oncorhynchus mykiss

Unknown authors · 2015

Iranian researchers exposed rainbow trout to 15 Hz electromagnetic fields at various intensities for one hour daily over 60 days. Fish showed improved growth, stronger immune responses, and better resistance to bacterial infection at most exposure levels. The study suggests extremely low frequency EMF may have beneficial effects on fish health.

D'Angelo C et al, (January 2015) Experimental model for ELF-EMF exposure: Concern for human health, Saudi J Biol Sci. 2015 Jan;22(1):75-84. doi: 10.1016/j.sjbs.2014.07.006

Unknown authors · 2015

Italian researchers exposed four different types of human cells to 50 Hz electromagnetic fields (the same frequency as power lines) at 1 mT strength for varying durations. They found that this exposure changed the production of MCP-1, a protein involved in immune system signaling, but the effects varied significantly between different cell types. The study suggests that power line frequency EMF can alter cellular immune responses, though more research is needed to understand the implications.

Influence of extremely low frequency electromagnetic fields on growth performance, innate immune response, biochemical parameters and disease resistance in rainbow trout, Oncorhynchus mykiss

Unknown authors · 2015

Researchers exposed rainbow trout to extremely low frequency electromagnetic fields (15 Hz) at various intensities for one hour daily over 60 days. The fish showed improved growth, stronger immune responses, and better disease resistance compared to unexposed controls. This suggests that certain EMF exposures may have beneficial biological effects in aquatic organisms.

DNA & Genetic DamageNo Effects Found

A Genotoxic Analysis on Hematopoietic system after Mobile Phone Type Radiation Exposure in Rats.

Kumar G, McIntosh RL, Anderson V, McKenzie RJ, Wood AW. · 2015

Researchers exposed rat bone marrow to mobile phone radiation at 900 and 1800 MHz frequencies to test for genetic damage and effects on blood cell production. They tested both continuous and pulsed signals at power levels ranging from 2 to 12.4 watts per kilogram. The study found no significant changes in cell growth or DNA damage in the bone marrow cells after exposure.

DNA & Genetic DamageNo Effects Found

A genotoxic analysis of the hematopoietic system after mobile phone type radiation exposure in rats.

Kumar G, McIntosh RL, Anderson V, McKenzie RJ, Wood AW. · 2015

Researchers exposed rat bone marrow to cell phone-type radiation at 900 MHz and 1800 MHz frequencies to test for DNA damage and changes in blood cell production. They found no significant effects on genetic damage or cell growth at radiation levels of 2-2.5 watts per kilogram, which are similar to current safety limits. This study suggests that short-term exposure to these specific radiation levels may not cause immediate DNA damage in blood-forming cells.

EMF radiation at 2450MHz triggers changes in the morphology and expression of heat shock proteins and glucocorticoid receptors in rat thymus.

Misa-Agustiño MJ et al. · 2015

Researchers exposed rats to 2.45 GHz radiofrequency radiation (the same frequency used in microwave ovens and WiFi) and found it caused visible damage to the thymus, a key immune system organ. The radiation triggered cellular stress responses, increased blood vessel leakage, and altered stress proteins even at levels below those that cause heating. This suggests that EMF exposure can disrupt immune system function through non-thermal biological mechanisms.

The effects of 2100-MHz radiofrequency radiation on nasal mucosa and mucociliary clearance in rats.

Aydoğan F et al. · 2015

Researchers exposed rats to 2100 MHz radiofrequency radiation (simulating 3G cell phone signals) for 6 hours daily over 10 or 40 days to study effects on nasal tissue and mucus clearance. The exposed rats showed significant damage to nasal tissue, including cell death, loss of protective cilia (tiny hair-like structures), and impaired ability to clear mucus from nasal passages. This matters because our nasal passages are a primary defense against airborne pathogens, and cell phone radiation may be compromising this natural protective mechanism.

Effect of 900 MHz Electromagnetic Radiation on the Induction of ROS in Human Peripheral Blood Mononuclear Cells.

Kazemi E et al. · 2015

Researchers exposed blood cells from 13 healthy volunteers to 900 MHz radiation (the frequency used by cell phones) for 2 hours and measured cellular damage. They found that exposure significantly increased reactive oxygen species (ROS) - harmful molecules that damage cells - in monocytes, a type of immune cell. This suggests that cell phone radiation can trigger oxidative stress in immune system cells.

Can prenatal exposure to a 900 MHz electromagnetic field affect the morphology of the spleen and thymus, and alter biomarkers of oxidative damage in 21-day-old male rats?

Hancı H et al. · 2015

Researchers exposed pregnant rats to 900 MHz cell phone radiation for one hour daily and examined the immune organs (spleen and thymus) of their male offspring at 21 days old. The prenatal radiation exposure caused significant oxidative damage and structural abnormalities in these critical immune system organs. This suggests that EMF exposure during pregnancy may compromise immune system development in offspring.

Immune SystemNo Effects Found

Rosado MM et al, (September 2014) Effects of GSM-modulated 900 MHz radiofrequency electromagnetic fields on the hematopoietic potential of mouse bone marrow cells, Bioelectromagnetics

Unknown authors · 2014

Italian researchers exposed mice to GSM-modulated 900 MHz radiofrequency fields (the same type used in cell phones) and then transplanted their bone marrow cells into other mice to test immune system function. After 12 weeks, they found no differences in immune cell development, numbers, or function between bone marrow from RF-exposed mice versus unexposed controls. The study suggests that cell phone-type radiation doesn't impair the bone marrow's ability to produce healthy immune cells.

Immune SystemNo Effects Found

Rosado MM et al, (September 2014) Effects of GSM-modulated 900 MHz radiofrequency electromagnetic fields on the hematopoietic potential of mouse bone marrow cells, Bioelectromagnetics

Unknown authors · 2014

Italian researchers exposed mice to 900 MHz GSM cell phone radiation and then transplanted their bone marrow cells into other mice to test immune system function. After 12 weeks, they found no differences in immune cell development, proliferation, or function between radiation-exposed and control groups. The study suggests that cell phone radiation doesn't impair the bone marrow's ability to produce healthy immune cells.

Immune SystemNo Effects Found

Effects of 21-kHz intermediate frequency magnetic fields on blood properties and immune systems of juvenile rats.

Ushiyama A et al. · 2014

Researchers exposed young rats to 21-kHz magnetic fields (similar to frequencies used in induction heating and some wireless charging) for one hour daily over two weeks to test effects on blood and immune system function. The study found no significant changes in immune cell activity, blood cell counts, or other immune markers, with only a minor phosphorus level change that remained within normal ranges. This suggests that short-term exposure to these intermediate-frequency magnetic fields may not substantially impact immune function in developing animals.

Non-linear adaptive phenomena which decrease the risk of infection after pre-exposure to radiofrequency radiation.

Mortazavi SM et al. · 2014

Researchers exposed mice to radiofrequency radiation from a GSM mobile phone, then infected them with E. coli bacteria to test their immune response. They found that pre-exposure to RF radiation dramatically improved survival rates - 56% of pre-exposed mice survived the bacterial infection compared to only 20% of unexposed mice. This suggests RF radiation may trigger an adaptive response that strengthens the immune system's ability to fight off infections.

Differential Pro-Inflammatory Responses of Astrocytes and Microglia Involve STAT3 Activation in Response to 1800 MHz Radiofrequency Fields.

Lu Y et al. · 2014

Researchers exposed brain immune cells (microglia and astrocytes) to 1800 MHz radiofrequency radiation - the same frequency used by many cell phones. They found that RF exposure triggered inflammatory responses in both cell types, but through different biological pathways. The study identified a specific protein (STAT3) that could be targeted to potentially protect against RF-induced brain inflammation.

A new problem in inflammatory bladder diseases: Use of mobile phones!

Koca O, Gokce AM, Akyuz M, Ercan F, Yurdakul N, Karaman MI. · 2014

Turkish researchers exposed laboratory rats to mobile phone radiation for 8 hours daily over 20 days and examined their bladder tissue under a microscope. They found severe inflammation in the bladder's inner layers in exposed rats, with inflammation scores nearly five times higher than unexposed controls. The study suggests that intensive mobile phone use may contribute to bladder inflammation and related urinary problems.

Effect of mobile phone use on salivary concentrations of protein, amylase, lipase, immunoglobulin A, lysozyme, lactoferrin, peroxidase and C-reactive protein of the parotid gland.

Hashemipour MS, Yarbakht M, Gholamhosseinian A, Famori H. · 2014

Researchers examined saliva from 86 people to see if mobile phone use affected the parotid glands (major salivary glands near the ears). They found that people who predominantly held phones on their right side had higher protein levels and saliva flow on that same side, while levels of important enzymes like amylase and lysozyme decreased. This suggests that radiofrequency radiation from phones may alter the normal function of salivary glands closest to where the phone is held.

Hsp70 is an independent stress marker among frequent users of mobile phones.

Balakrishnan K et al. · 2014

Researchers compared blood markers between 120 heavy mobile phone users (IT professionals) and 102 light users to see if phone radiation triggers stress responses in the body. They found significantly elevated levels of heat shock protein 70 (HSP70) and C-reactive protein (CRP) in heavy users, indicating cellular stress and inflammation. This suggests that frequent mobile phone use may activate biological stress pathways that could potentially impact health over time.

Metabolic and genetic screening of electromagnetic hypersensitive subjects as a feasible tool for diagnostics and intervention.

De Luca C et al. · 2014

Italian researchers analyzed blood samples from 153 people with electromagnetic hypersensitivity (EHS) and found distinctive metabolic changes including increased oxidative stress and specific genetic variations. These blood markers could potentially serve as diagnostic tools to identify EHS as a legitimate medical condition.

Browse by Health Effect