3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 1,359 studies (Human Studies)

Competition between hydrogen bonding and protein aggregation in neuronal-like cells under exposure to 50 Hz magnetic field.

Calabrò E. · 2016

Researchers exposed human brain-like cells to a 50 Hz magnetic field (the type emitted by power lines and household appliances) for 4 hours and found significant changes in cellular proteins. The magnetic field caused proteins to clump together abnormally and altered their structural bonds, which are critical for proper brain cell function. These molecular changes suggest that everyday electromagnetic fields may disrupt normal cellular processes in brain tissue.

The 2100MHz radiofrequency radiation of a 3G-mobile phone and the DNA oxidative damage in brain.

Şahin D et al. · 2016

Researchers exposed female rats to 3G mobile phone radiation (2100 MHz) for either 10 or 40 days to study DNA damage in brain tissue. They found increased DNA damage after 10 days of exposure, but surprisingly, this damage decreased after 40 days, suggesting the brain may develop protective mechanisms over time. The study used radiation levels similar to what you'd experience during heavy mobile phone use.

Effects of long-term exposure to 900 megahertz electromagnetic field on heart morphology and biochemistry of male adolescent rats.

Kerimoğlu G et al. · 2016

Researchers exposed adolescent male rats to cell phone-level radiation (900 MHz) for one hour daily during their development and examined their hearts as adults. The exposed rats showed significant heart damage including increased oxidative stress, structural changes to heart muscle cells, and higher rates of cell death compared to unexposed controls. This suggests that EMF exposure during critical developmental periods may cause lasting cardiovascular damage.

Effects of extremely low-frequency electromagnetic field on expression levels of some antioxidant genes in human MCF-7 cells.

Mahmoudinasab H, Sanie-Jahromi F, Saadat M · 2016

Researchers exposed breast cancer cells to 50 Hz electromagnetic fields (household electricity frequency) for 30 minutes. Stronger fields significantly altered genes that protect cells from damage, especially during on-off exposure patterns. This shows brief EMF exposure can disrupt cellular defense systems.

Induction of micronuclei and superoxide production in neuroblastoma and glioma cell lines exposed to weak 50 Hz magnetic fields.

Kesari KK, Juutilainen J, Luukkonen J, Naarala J. · 2016

Researchers exposed brain cells to extremely low frequency magnetic fields (the type from power lines) at levels as low as 10 microtesla for 24 hours. The study found significant DNA damage in human neuroblastoma cells and increased oxidative stress in rat brain cells. These effects occurred at magnetic field levels that are commonly encountered near electrical appliances and power infrastructure.

The developmental effects of extremely low frequency electric fields on visual and somatosensory evoked potentials in adult rats

Gok DK et al. · 2016

Researchers exposed pregnant rats and their offspring to 50 Hz electric fields (the same frequency as household electricity) and measured brain wave responses to visual and touch stimuli. The exposed animals showed delayed brain responses and increased oxidative damage in both brain and retinal tissue compared to unexposed controls. This suggests that electric field exposure during development can impair nervous system function through cellular damage mechanisms.

Mitochondrial ROS release and subsequent Akt Activation potentially mediated the anti-apoptotic effect of a 50-Hz magnetic field on FL cells.

Feng B, Ye C, Qiu L, Chen L, Fu Y, Sun W · 2016

Researchers exposed human cells to a 50-Hz magnetic field (the same frequency as power lines) and found it protected cells from dying when they were later exposed to a toxic chemical. The magnetic field triggered the release of reactive oxygen species from mitochondria (the cell's power plants), which activated protective cellular pathways. This suggests extremely low frequency magnetic fields can influence fundamental cellular survival mechanisms.

NADPH oxidase-produced superoxide mediated a 50-Hz magnetic field-induced epidermal growth factor receptor clustering

Feng B, Dai A, Chen L, Qiu L, Fu Y, Sun W. · 2016

Researchers exposed human cells to 50 Hz magnetic fields (the same frequency used in household electricity) and found that even brief exposures triggered increased production of reactive oxygen species - harmful molecules that can damage cells. The magnetic fields caused specific cellular receptors to cluster together abnormally, a process linked to various health problems including cancer development.

Exposure to a 50-Hz magnetic field induced mitochondrial permeability transition through the ROS/GSK-3β signaling pathway.

Feng B, Qiu L, Ye C, Chen L, Fu Y, Sun W. · 2016

Chinese researchers exposed human cells to magnetic fields at levels similar to those found near power lines and appliances (0.4 mT for 60 minutes). They discovered that this exposure damaged the powerhouses of cells (mitochondria) by triggering a harmful chain reaction involving oxidative stress. The damage occurred through a specific biological pathway that could be blocked with antioxidants, suggesting the effects are real and measurable.

Pulsed electromagnetic field (PEMF) prevents pro-oxidant effects of H2O2 in SK-N-BE(2) human neuroblastoma cells.

Falone S et al. · 2016

Researchers exposed drug-resistant brain cancer cells to pulsed electromagnetic fields (PEMF) at 75 Hz for brief periods over five days, then tested how well the cells handled oxidative stress. The PEMF treatment boosted the cells' antioxidant defenses and reduced harmful reactive oxygen species when challenged with hydrogen peroxide. This suggests that specific electromagnetic field exposures might actually help protect cells from oxidative damage rather than harm them.

Exposure to electromagnetic field attenuates oxygen-glucose deprivation-induced microglial cell death by reducing intracellular Ca2+ and ROS.

Duong CN, Kim JY · 2016

Researchers exposed human brain immune cells to magnetic fields at 50 Hz while depriving them of oxygen to mimic stroke conditions. The magnetic field exposure protected cells from dying by reducing harmful calcium and oxidative stress, suggesting potential therapeutic applications for stroke treatment.

Extremely low frequency magnetic field (ELF-MF) exposure sensitizes SH-SY5Y cells to the pro-Parkinson's Disease toxin MPP.

Benassi B et al. · 2016

Italian researchers exposed brain cells to 50 Hz magnetic fields, then tested their response to a Parkinson's toxin. While EMF alone didn't harm cells, it weakened their antioxidant defenses, making them far more vulnerable to the toxin's damage, suggesting EMF might increase susceptibility to Parkinson's disease.

2100-MHz electromagnetic fields have different effects on visual evoked potentials and oxidant/antioxidant status depending on exposure duration.

Hidisoglu E et al. · 2016

Researchers exposed rats to 2100-MHz radiofrequency radiation (similar to 3G cell phone signals) for 2 hours daily, comparing short-term (1 week) versus long-term (10 weeks) exposure. They found that short-term exposure actually improved brain function and antioxidant defenses, while long-term exposure caused brain dysfunction and oxidative damage. This suggests that duration of EMF exposure matters significantly for health effects.

Cancer & TumorsNo Effects Found

Mobile phone use and risk of glioma: a case-control study in Korea for 2002-2007.

Yoon S, Choi JW, Lee E, Ahn H, Kim HS, Choi HD, Kim N. · 2015

Korean researchers studied 285 brain tumor patients and 285 healthy controls to investigate whether mobile phone use increases the risk of gliomas, a serious type of brain cancer. The study found no significant overall increase in brain tumor risk from mobile phone use, though there was a non-significant trend toward higher risk when people used phones on the same side of their head where the tumor developed. The researchers concluded their findings don't support the idea that mobile phones cause brain tumors, but suggested more research is needed for long-term users.

Cancer & TumorsNo Effects Found

Pituitary tumor risk in relation to mobile phone use: A case-control study.

Shrestha M, Raitanen J, Salminen T, Lahkola A, Auvinen A · 2015

Finnish researchers studied whether mobile phone use increases the risk of pituitary tumors by comparing 80 tumor patients with 240 healthy controls. They found no increased risk of pituitary tumors from mobile phone use, even after 10 years of use. However, the study had limited data on very long-term users (beyond 10 years), so questions remain about potential risks from decades of use.

Sleep & Circadian RhythmNo Effects Found

Symptoms and Cognitive Functions in Adolescents in Relation to Mobile Phone Use during Night.

Schoeni A, Roser K, Röösli M. · 2015

Researchers studied 439 Swiss adolescents to see how nighttime mobile phone interruptions affect their health and thinking abilities. They found that teens awakened by phones at least once monthly were 86% more likely to experience daytime tiredness and over twice as likely to feel rapidly exhausted. However, the interruptions didn't impair memory or concentration on cognitive tests, suggesting the main impact is on energy levels rather than mental performance.

Brain & Nervous SystemNo Effects Found

Do signals of a hand-held TETRA transmitter affect cognitive performance, well-being, mood or somatic complaints in healthy young men? Results of a randomized double-blind cross-over provocation study.

Sauter C et al. · 2015

German researchers exposed 30 healthy young men to TETRA radio signals (used by police and emergency services) for 2.5 hours to test effects on thinking, mood, and physical symptoms. They found no negative impacts on cognitive performance or well-being, with some participants actually showing slight improvements in certain memory tasks. The study suggests short-term exposure to TETRA signals doesn't harm mental function in healthy adults.

Oxidative StressNo Effects Found

Multivariate Entropy Analysis of Oxidative Stress Biomarkers Following Mobile Phone Exposure of Human Volunteers: A Pilot Study

Marconi A et al. · 2015

Researchers exposed 18 volunteers to GSM mobile phone signals for 30 minutes and measured various oxidative stress markers in their blood and breath. While they found no harmful effects, they discovered that phone exposure changed how these biological markers were organized in the body, creating a more ordered pattern. This suggests that mobile phone radiation does interact with biological systems, even if the health consequences aren't yet clear.

Sleep & Circadian RhythmNo Effects Found

Inter-individual and intra-individual variation of the effects of pulsed RF EMF exposure on the human sleep EEG.

Lustenberger et al. · 2015

Swiss researchers exposed 20 young men to cell phone-level radiation (900 MHz at 2 watts per kilogram) for 30 minutes before sleep on two separate nights, then monitored their brain activity throughout the night using EEG. While they found some increases in certain brain wave patterns during deep sleep, these effects were inconsistent - they didn't reliably occur in the same individuals across both exposure sessions. This suggests that if cell phone radiation affects sleep brain activity, the response varies unpredictably between people and even within the same person on different nights.

Cancer & TumorsNo Effects Found

Exposure to 3G mobile phone signals does not affect the biological features of brain tumor cells.

Liu YX et al. · 2015

Researchers exposed human brain tumor cells to 3G mobile phone radiation (1950-MHz) for up to 48 hours at high power levels (SAR of 5 W/kg) to see if the radiation would promote tumor growth or change cell behavior. They found no significant effects on cell growth, gene expression, or tumor formation ability. This suggests that 3G signals at these exposure levels don't act as tumor-promoting agents in already-existing brain cancer cells.

Brain & Nervous SystemNo Effects Found

Effect of Prolonged Use of Mobile Phone on Brainstem Auditory Evoked Potentials.

Gupta N, Goyal D, Sharma R, Arora KS. · 2015

Researchers tested whether long-term mobile phone use affects the auditory brainstem (the part of the brain that processes sound signals from the ear). They compared brain wave responses in 67 people who had used GSM phones for over a year with 33 non-users, all aged 18-30. The study found no significant differences in how sound signals traveled through the auditory system between phone users and non-users.

Cancer & TumorsNo Effects Found

First epidemiological study on occupational radar exposure in the French Navy: a 26-year cohort study.

Dabouis V et al. · 2015

French researchers tracked 57,000 naval personnel over 26 years to compare death rates between those working with radar systems and those in non-radar roles. They found no increased risk of death from any cause, including cancer, among radar-exposed workers compared to unexposed personnel. This large-scale occupational study suggests that the radiofrequency radiation from naval radar systems did not significantly impact mortality rates during the study period.

Brain & Nervous SystemNo Effects Found

Effects of extremely low frequency electromagnetic fields (100μT) on behaviors in rats.

Lai J et al. · 2015

Researchers exposed adult male rats to 50 Hz magnetic fields at 100 microtesla for 24 weeks and tested their behavior, memory, and brain structure. The study found no effects on anxiety, depression, learning ability, or brain tissue compared to unexposed rats. This suggests that prolonged exposure to this level of extremely low frequency magnetic fields may not cause behavioral or cognitive problems.

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