3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 1,644 studies in Brain & Nervous System

Effect of radiofrequency electromagnetic field exposure on in vitro models of neurodegenerative disease

Del Vecchio G et al. · 2009

Italian researchers exposed brain cells to cell phone radiation (900 MHz GSM at 1 W/kg SAR) for 144 hours to see if it made them more vulnerable to damage. While the radiation alone didn't harm the cells, it made one type of brain cell significantly more vulnerable to damage from hydrogen peroxide, a common cellular toxin that causes oxidative stress.

Mobile phones exposure induces changes of contingent negative variation in humans

de Tommaso M et al. · 2009

Italian researchers exposed 10 volunteers to cell phone radiation at 900 MHz and measured their brain's electrical activity using EEG. They found that both active phones and phones with blocked radiation (but still powered on) reduced brain arousal and expectation responses compared to phones that were completely off. This suggests that cell phone exposure affects how the brain processes and anticipates information.

Effect of mobile phone exposure on apoptotic glial cells and status of oxidative stress in rat brain

Dasdag S, Akdag MZ, Ulukaya E, Uzunlar AK, Ocak AR · 2009

Researchers exposed rats to 900 MHz cell phone radiation for 2 hours daily over 10 months to study brain cell death (apoptosis) and oxidative stress. Surprisingly, they found reduced cell death and increased antioxidant activity in exposed rats compared to controls. This unexpected finding suggests the brain may activate protective mechanisms in response to chronic low-level radiation exposure.

Acute mobile phones exposure affects frontal cortex hemodynamics as evidenced by functional near-infrared spectroscopy

Curcio G et al. · 2009

Researchers used brain imaging technology to measure blood flow changes in the frontal cortex of 11 volunteers during 40 minutes of cell phone exposure. They found that real phone exposure caused a gradual increase in deoxygenated blood in brain tissue compared to fake exposure, indicating altered brain activity. This suggests that even brief cell phone use can measurably change how blood flows through critical brain regions.

900 MHz electromagnetic field exposure affects qualitative and quantitative features of hippocampal pyramidal cells in the adult female rat

Bas O, Odaci E, Kaplan S, Acer N, Ucok K, Colakoglu S · 2009

Researchers exposed female rats to cell phone radiation (900 MHz) for one hour daily over 28 days. They found significant loss of brain cells in the hippocampus, the brain region responsible for memory and learning, raising concerns about potential effects from regular phone use.

Enhancement of chemically induced reactive oxygen species production and DNA damage in human SH-SY5Y neuroblastoma cells by 872MHz radiofrequency radiation.

Luukkonen J et al. · 2009

Researchers exposed human brain cells to radiofrequency radiation at 872 MHz (similar to older cell phone frequencies) combined with a chemical that creates cellular damage. They found that continuous wave RF radiation at high intensity (5 W/kg SAR) increased both harmful oxygen molecules and DNA damage compared to the chemical alone. Interestingly, pulsed signals like those used in GSM phones showed no such effects, even at the same power level.

Fifty-gigahertz Microwave exposure effect of radiations on rat brain.

Kesari KK, Behari J. · 2009

Researchers exposed rats to 50-gigahertz microwave radiation (similar to 5G frequencies) for 2 hours daily over 45 days at very low power levels. The study found significant DNA damage in brain cells, along with disrupted antioxidant defenses and decreased protein kinase C activity. These cellular changes suggest that even low-level millimeter wave exposure may affect brain function and cellular health.

Continuous exposure to 900MHz GSM-modulated EMF alters morphological maturation of neural cells.

Del Vecchio G et al. · 2009

Italian researchers exposed developing brain cells to cell phone radiation at levels similar to what phones emit (1 W/kg SAR at 900 MHz). They found that this radiation significantly reduced the growth of neurites - the branch-like extensions that neurons use to connect and communicate with each other. This suggests that cell phone radiation may interfere with normal brain cell development and connection formation.

Cellular EffectsNo Effects Found

Whole-body exposure of radiation emitted from 900 MHz mobile phones does not seem to affect the levels of anti-apoptotic bcl-2 protein.

Yilmaz F, Dasdag S, Akdag MZ, Kilinc N. · 2008

Researchers exposed rats to radiation from 900 MHz cell phones for 20 minutes daily for one month to see if it affected bcl-2, a protein that helps prevent cell death in the brain and testes. They found no changes in bcl-2 levels compared to unexposed rats. This suggests that at least for this specific cellular protection mechanism, short-term phone radiation exposure may not cause immediate harm to these organs.

Brain & Nervous SystemNo Effects Found

No effect of an UMTS mobile phone-like electromagnetic field of 1.97 GHz on human attention and reaction time.

Unterlechner M, Sauter C, Schmid G, Zeitlhofer J. · 2008

Researchers exposed 40 healthy volunteers to UMTS mobile phone-like electromagnetic fields at 1.97 GHz while testing their attention and reaction time on computer tasks. The study found no statistically significant effects on cognitive performance, even at exposure levels up to 1.49 W/kg SAR (specific absorption rate, a measure of how much energy the body absorbs). This suggests that short-term exposure to 3G mobile phone signals does not immediately impair basic cognitive functions like attention and reaction speed.

Symptoms & SensitivityNo Effects Found

Nocebo as headache trigger: evidence from a sham-controlled provocation study with RF fields.

Stovner LJ, Oftedal G, Straume A, Johnsson A · 2008

Norwegian researchers studied 17 people who reported getting headaches from mobile phone use, exposing them to both real radiofrequency (RF) signals and fake exposures in a controlled setting. Participants experienced the same types of headaches whether they were exposed to actual RF fields or just thought they were, suggesting their 'mobile phone headaches' were caused by negative expectations (called the nocebo effect) rather than the electromagnetic fields themselves.

Brain & Nervous SystemNo Effects Found

Cognitive function and symptoms in adults and adolescents in relation to rf radiation from UMTS base stations.

Riddervold IS et al. · 2008

Danish researchers tested whether 45-minute exposures to UMTS cell tower radiation (2140 MHz) affected cognitive performance and symptoms in 40 teenagers and 40 adults. They found no significant differences in cognitive test performance between real and sham exposures, though participants reported slightly more headaches during radiation exposure, which may have been due to baseline differences rather than the radiation itself.

Brain & Nervous SystemNo Effects Found

No evidence of major transcriptional changes in the brain of mice exposed to 1800 MHz GSM signal.

Paparini A et al. · 2008

Researchers exposed mice to GSM cell phone radiation (1800 MHz) for one hour and analyzed gene expression changes in brain tissue using advanced genetic screening techniques. They found no significant changes in brain gene expression patterns, even when using less strict analysis methods that initially suggested 75 genes might be affected. This study suggests that short-term exposure to cell phone-level radiation may not cause major genetic changes in brain tissue.

Cancer & TumorsNo Effects Found

Meningioma and mobile phone use--a collaborative case-control study in five North European countries.

Lahkola A et al. · 2008

Researchers studied 1,209 people with meningiomas (a type of brain tumor) and 3,299 healthy controls across five European countries to see if mobile phone use increases tumor risk. They found that regular mobile phone users actually had a 24% lower risk of developing meningiomas compared to non-users or occasional users. The study found no increased risk regardless of how long people used phones, how many calls they made, or what type of network they used.

Brain & Nervous SystemNo Effects Found

Effects of weak mobile phone - electromagnetic fields (GSM, UMTS) on event related potentials and cognitive functions.

Kleinlogel H et al. · 2008

Researchers tested whether cell phone radiation from GSM and UMTS networks affects brain activity and cognitive performance in 15 healthy adults. They measured brain waves and reaction times during various mental tasks while participants were exposed to phone radiation at levels typical of actual phone use. The study found no significant changes in brain activity or cognitive function during EMF exposure compared to fake (sham) exposure.

Brain & Nervous SystemNo Effects Found

Effects of weak mobile Phone-Electromagnetic fields (GSM, UMTS) on well-being and resting EEG.

Kleinlogel H et al. · 2008

Researchers exposed 15 healthy adults to electromagnetic fields from both GSM (2G) and UMTS (3G) mobile phones while measuring their brain activity with EEG and asking about their well-being. They found no significant changes in brain wave patterns or reported symptoms compared to fake (sham) exposure. The study suggests that typical mobile phone radiation levels don't produce detectable immediate effects on brain activity in healthy users.

Brain & Nervous SystemNo Effects Found

Local exposure of 849 MHz and 1763 MHz radiofrequency radiation to mouse heads does not induce cell death or cell proliferation in brain.

Kim TH et al. · 2008

Researchers exposed mice to cell phone radiation at 849 MHz and 1763 MHz frequencies for up to 12 months, using radiation levels about 4 times higher than current safety limits. They found no changes in brain cell death, cell growth, or tissue damage compared to unexposed mice. This suggests that chronic exposure to these specific frequencies at high levels may not cause detectable brain tissue changes in mice.

Brain & Nervous SystemNo Effects Found

Characterization of biological effect of 1763 MHz radiofrequency exposure on auditory hair cells.

Huang TQ et al. · 2008

Researchers exposed mouse auditory hair cells (the cells responsible for hearing) to cell phone radiation at 1763 MHz for up to 48 hours at extremely high power levels - 10 times stronger than typical phone use. They found no DNA damage, no changes in cell cycles, no stress responses, and only 29 out of 32,000 genes showed any change. The study suggests that even at these high exposure levels, cell phone radiation doesn't cause measurable biological damage to the specialized cells in our ears.

Brain & Nervous SystemNo Effects Found

Histopathological examinations of rat brains after long-term exposure to GSM-900 mobile phone radiation.

Grafström G et al. · 2008

Swedish researchers exposed rats to GSM-900 cell phone radiation once weekly for over a year at power levels similar to what humans experience during phone calls. When they examined the rats' brains afterward, they found no signs of damage including blood-brain barrier leakage, cell death, or aging-related changes. This suggests that intermittent cell phone radiation exposure at typical usage levels may not cause detectable brain tissue damage.

Symptoms & SensitivityNo Effects Found

Exposure to mobile phone electromagnetic fields and subjective symptoms: a double-blind study.

Cinel C, Russo R, Boldini A, Fox E. · 2008

Researchers exposed 496 volunteers to mobile phone radiation in a controlled, double-blind study to see if it caused symptoms like headaches or dizziness. They found only one inconsistent effect - dizziness in one group that wasn't replicated in the other groups. The study concluded there's no consistent evidence that mobile phone radiation causes immediate physical symptoms.

Oxidative StressNo Effects Found

Effects of exposure to 50 Hz electric field at different strengths on oxidative stress and antioxidant enzyme activities in the brain tissue of guinea pigs.

Türközer Z, Güler G, Seyhan N · 2008

Researchers exposed guinea pigs to powerful electric fields (the kind found near high-voltage power lines) for 8 hours daily over three days to see if it would damage brain tissue through oxidative stress. They found no statistically significant effects on brain cell damage markers or antioxidant defenses, even at the highest exposure levels tested. While this suggests these particular electric field exposures may not cause measurable brain oxidative damage in the short term, the researchers noted some non-significant trends that warrant further investigation.

Oxidative StressNo Effects Found

Effects of exposure to 50 Hz electric field at different strengths on oxidative stress and antioxidant enzyme activities in the brain tissue of guinea pigs.

Türközer Z, Güler G, Seyhan N. · 2008

Researchers exposed guinea pigs to 50 Hz electric fields at various strengths (from 2,000 to 5,000 volts per meter) for 8 hours daily over three days, then measured markers of oxidative stress in brain tissue. The study found no statistically significant changes in cellular damage markers or antioxidant enzyme activity, though some non-significant trends were observed. This suggests that short-term exposure to these electric field levels may not cause measurable oxidative stress in brain tissue.

Cellular EffectsNo Effects Found

Whole-body exposure of radiation emitted from 900 MHz mobile phones does not seem to affect the levels of anti-apoptotic bcl-2 protein.

Yilmaz F, Dasdag S, Akdag MZ, Kilinc N · 2008

Turkish researchers exposed rats to radiation from 900 MHz cell phones for 20 minutes daily over one month to see if it affected bcl-2, a protein that helps prevent cell death in the brain and reproductive organs. They found no changes in bcl-2 levels in either brain or testicular tissue. This suggests that at least for this specific protein marker, short-term cell phone radiation exposure may not trigger cellular death pathways in these organs.

Brain & Nervous SystemNo Effects Found

No effect of an UMTS mobile phone‐like electromagnetic field of 1.97 GHz on human attention and reaction time

Unterlechner M, Sauter C, Schmid G, Zeitlhofer J · 2008

Researchers exposed 40 healthy adults to 3G mobile phone signals at 1.97 GHz for 90 minutes while testing their attention and reaction time through computer tasks. The study found no immediate effects on cognitive performance at exposure levels up to 0.63 W/kg SAR (specific absorption rate), which represents the amount of RF energy absorbed by brain tissue. This suggests that short-term exposure to 3G phone signals does not impair basic mental functions like attention and reaction speed.

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