Wang H et al. · 2013
Researchers exposed 100 Wistar rats to a 2.856 GHz pulsed microwave field at average power densities of 0, 5, 10, and 50 mW/cm² for 6 minutes. Rats exposed to 10 or 50 mW/cm² showed significant deficits in spatial learning and memory at 6 hours, 1 day, and 3 days after exposure. At the 5 mW/cm² level, exposed rats showed no difference compared with the sham group. The study suggested that impairment of LTP induction and damages of hippocampal structure, especially changes of synapses, might contribute to cognitive impairment after microwave exposure.
Vecsei Z, Csathó A, Thuróczy G, Hernádi I · 2013
Researchers tested the effects of UMTS RF EMF exposure on the thermal pain threshold of 20 young adult volunteers, measuring responses on the surface of the fingers. The exposure lasted 30 minutes and was applied to the head through a patch antenna, with SAR kept constant at 1.75 W/kg. Thermal pain thresholds were intact, but a reduced desensitization effect between repeated stimulations was observed on the contralateral side during genuine UMTS exposure. Subjective pain ratings were marginally decreased in the genuine exposure condition only.
Sharma A, Sisodia R, Bhatnagar D, Saxena VK · 2013
Researchers exposed Swiss albino mice to 10 GHz microwaves at a power density of 0.25 mW/cm2 for 2 hours per day for 30 days, then tested spatial memory using the Morris water maze test. Exposed mice showed statistically significant higher mean latency to reach the target quadrant compared to sham-exposed mice. A decrease in protein levels was also estimated in the whole brain of exposed mice compared to sham-exposed mice.
Lv B, Chen Z, Wu T, Shao Q, Yan D, Ma L, Lu K, Xie Y. · 2013
Eighteen subjects participated in a double-blind, crossover, randomized and counterbalanced experiment including real and sham exposure sessions. Resting-state fMRI signals were collected before and after exposure, with the radiation source placed close to the right ear. After real exposure, decreased ALFF values were found in the left superior temporal gyrus, left middle temporal gyrus, right superior temporal gyrus, right medial frontal gyrus, and right paracentral lobule.
Hao D, Yang L, Chen S, Tong J, Tian Y, Su B, Wu S, Zeng Y · 2013
Researchers exposed 32 trained Wistar rats to 916 MHz, 10w/m2 electromagnetic field for 6 hours a day, 5 days a week, over 10 weeks, and tested their spatial learning and memory in an eight-arm radial maze each weekend. During weeks 4–5, the exposed rats had longer completion times and higher error rates than the control group, but during weeks 1–3 and 6–9 the two groups were close to each other. The researchers concluded that the 916 MHz EMF influenced learning and memory in rats to some extent in a period during exposure, and that the rats can adapt to long-term EMF exposure.
Deshmukh PS et al. · 2013
The study investigated possible DNA-damaging effects of low-level microwave radiation in the brains of male Fischer rats. Rats were exposed for 30 days at three frequencies: 900, 1800, and 2450 MHz, at specific absorption rates on the order of 10−4 W/kg. DNA damage in brain tissue was assessed using alkaline comet assay after the exposure period. The researchers concluded that low SAR microwave radiation at these frequencies may induce DNA strand breaks in brain tissue.
Deshmukh PS et al. · 2013
Baş O et al. · 2013
Researchers exposed pregnant rats to a 900 MHz electromagnetic field on days 13 through 21 of pregnancy, then examined the brains of their female pups on postnatal day 32. Exposure during those prenatal days led to a significant decrease in the number of pyramidal cells in the cornu ammonis of the female rat pups (P<0.05). Histopathological examination also revealed picnotic cells in the cornu ammonis of the exposed female rat pups.
Banaceur S, Banasr S, Sakly M, Abdelmelek H · 2013
Researchers studied the effects of 2.4 GHz radiofrequency signals on wildtype mice and triple transgenic mice bred to develop Alzheimer's-like cognitive impairment. Mice were exposed two hours per day during one month at a Specific Absorption Rate of 1.60 W/kg. The researchers reported that radiofrequency exposure improved cognitive behavior in the 3xTg-AD mice.
Aboul Ezz HS, Khadrawy YA, Ahmed NA, Radwan NM, El Bakry MM · 2013
Researchers investigated the effect of electromagnetic radiation on concentrations of dopamine, norepinephrine, and serotonin in the hippocampus, hypothalamus, midbrain, and medulla oblongata of adult rats. Adult rats were exposed daily to electromagnetic radiation at 1800 MHz, with a specific absorption rate of 0.843 W/kg and power density of 0.02 mW/cm2, modulated at 217 Hz. Measurements were taken after 1, 2, and 4 months of daily exposure, and also after stopping exposure for 1 month following 4 months of daily exposure. The exposure resulted in significant changes in dopamine, norepinephrine, and serotonin in all four brain areas studied.
Unknown authors · 2012
Researchers conducted a comprehensive investigation of emotional and cognitive behavior in adult mice repeatedly exposed to a 7 Tesla static magnetic field in utero. Using well-validated tests, they did not observe any adverse behavioral alterations regarding emotional behavior as well as spatial and emotional learning. The study was motivated by increasing use of MRI in obstetrics and development of higher-performance systems with stronger fields requiring ongoing safety evaluation. Rodent studies provide an excellent opportunity to investigate acute and long-term effects of magnetic field exposure systematically.
Unknown authors · 2012
Wallace D et al. · 2012
Researchers conducted a randomized double-blind provocation study to test whether short-term exposure to a TETRA base station signal affects health and well-being. Fifty-one electrosensitive individuals and 132 matched controls took part, with 48 electrosensitive and 132 control participants completing double-blind tests in a screened semianechoic chamber. Under double-blind conditions, no differences were found on any measure between TETRA and sham exposure, and neither group could detect the signal above chance. When conditions were not double-blind, electrosensitive participants reported feeling worse and more severe symptoms during TETRA exposure. The researchers suggest that adverse symptoms in electrosensitive individuals are due to the belief of harm from TETRA base stations.
Hardell L, Carlberg M, Hansson Mild K. · 2012
Researchers conducted a meta-analysis of the Hardell group and Interphone studies on mobile phone use and brain tumours. The meta-analysis found an odds ratio of 1.71 for glioma in the temporal lobe in the latency group of 10 years or more. For ipsilateral mobile phone use with a latency of 10 years or more, the odds ratio for acoustic neuroma was 1.81. The analysis also reported an odds ratio of 2.29 for ipsilateral mobile phone use of 1640 hours or more, and an odds ratio of 2.55 for ipsilateral cumulative use of 1640 hours or more. The Hardell group studies also found that cordless phone use increased the risk for glioma and acoustic neuroma.
Ghosn R et al. · 2012
Volunteers participated in a double-blind, crossover study with sham and real GSM 900 MHz mobile phone exposure sessions lasting 20 minutes each. Middle cerebral artery blood flow velocity, pulsatility index, and resistance index were measured noninvasively with transcranial Doppler sonography before, during, and after exposure. No significant changes were detected in studied variables in middle cerebral arteries during sham or real exposure.
Deltour I et al. · 2012
Researchers analyzed annual age-standardized glioma incidence rates in men and women aged 20 to 79 years in the Nordic countries from 1979 to 2008 using joinpoint regression, including 35,250 cases. Incidence rates decreased in young men since 1987, remained stable in middle-aged men, and increased slightly in older men, with an overall annual percent change of 0.4% in men and 0.3% in women. Simulations indicated that relative risks of 2.0 for up to 15 years, 1.5 for up to 10 years, and 1.2 for up to 5 years for all users, as well as risks of 2.0 for up to 5 years for heavy users, were incompatible with observed trends.
Wallace D et al. · 2012
Researchers exposed Fifty-one people who reported perceived sensitivity to electromagnetic fields and 132 controls to a 420 MHz TETRA signal at 10 mW/m² and sham conditions under double-blind conditions. Cognitive measures of short-term memory, working memory, and attention were administered while physiological responses including blood volume pulse, heart rate, and skin conductance were monitored. No differences in cognitive performance or physiological responses were observed between TETRA exposure and sham in either group.
Kwon MS et al. · 2012
Researchers investigated effects of 902.4 MHz GSM radiation on cerebral blood flow using PET with 15O-water tracer. Fifteen young healthy men were exposed to radiation at three head locations and sham exposure while performing a visual task. Exposure caused slight ear canal temperature rise but did not affect brain hemodynamics or task performance. Results showed no evidence of acute effects on cerebral blood flow.
Dogan M et al. · 2012
Rats were randomly assigned to an exposed group (n=9) and a control group (n=9), with the exposed group subjected to electromagnetic radiation for 20 days. Researchers measured choline, creatinin, and N-acetylaspartate levels by magnetic resonance spectroscopy, catalase and glutathione peroxidase activities by spectrophotometry, and apoptosis by histopathology. No significant differences were found in NAA/Cr, Cho/Cr, or NAA/Cho ratios between the exposed and control groups. Oxidative stress parameters and apoptotic cell counts also showed no significant differences between groups.
Curcio G et al. · 2012
The study aimed to investigate the effects of GSM signal exposure on brain BOLD response and its time course during a Go-NoGo task. Participants were tested twice, once with real GSM radiofrequency signal exposure and once with a sham exposure as a placebo condition. BOLD response and reaction times were measured before and after exposure while participants performed the task. Reaction times to the somatosensory task did not change with real versus sham exposure, and Go responses activated the inferior parietal lobule, insula, precentral and postcentral gyri similarly after both exposures with no significant ROI effects.
Sudan M, Kheifets L, Arah O, Olsen J, Zeltzer L. · 2012
Researchers used data from the Danish National Birth Cohort, which enrolled pregnant women from 1996 to 2002, and assessed children at age seven via maternal questionnaire. They analyzed 52,680 children using multivariable adjusted models to relate prenatal only, postnatal only, or both prenatal and postnatal cell phone exposure to migraines and headache-related symptoms. Children with both prenatal and postnatal exposure had higher odds of migraines (OR 1.30, 95% CI 1.01-1.68) and headache-related symptoms (OR 1.32, 95% CI 1.23-1.40) compared to unexposed children.
Li CY, Liu CC, Chang YH, Chou LP, Ko MC. · 2012
Researchers conducted a population-based case-control study in Taiwan of children aged 15 or younger diagnosed with neoplasms between 2003 and 2007. Exposure to radiofrequency radiation was estimated from the annual power density of mobile phone base stations in each township over the five years before diagnosis. Higher-than-median exposure was significantly associated with increased odds of all neoplasms combined, but not with leukemia or brain neoplasms individually.
Hardell L, Carlberg M. · 2012
Researchers analyzed survival of glioma patients in relation to wireless phone use. For glioma overall, wireless phone use gave a hazard ratio of 1.1, and with more than 10-year latency the hazard ratio was 1.2. Low-grade astrocytoma showed a hazard ratio of 0.5, while glioblastoma showed a hazard ratio of 1.1, increasing to 1.3 with long latency. In the highest cumulative use tertile (>426 hours), glioblastoma hazard ratio was 1.2. The study included 1,251 malignant brain tumor cases diagnosed 1997–2003, followed until May 2012.
Gultekin DH, Moeller L. · 2012
Researchers described a method for measuring absorbed electromagnetic energy from cell phone antennae into ex vivo brain tissue. The method uses NMR thermometry to measure temperature increases via resonance frequency shifts of hydrogen protons. NMR imaging revealed 3D thermal dynamics in ex vivo bovine brain tissue and gel under varying RF fields. Specific absorption rate measurements averaged over 1 mg and 10 s covered the total absorption volume. Fiber optic temperature sensors confirmed the accuracy of the NMR thermometry.
Celikozlu SD et al. · 2012
Researchers exposed rats to magnetic fields via cell phones during prenatal and postnatal periods until the rats were 80 days old. The study measured blood parameters and neurons in the brain of rats. Magnetic field exposure decreased pyramidal neuron numbers 51.15% and increased ischemic neuron numbers 73% at the cortex region of the brain. In the hippocampus, magnetic fields increased the amount of ischemic neurons three-fold compared to the control, while hippocampal pyramidal cell numbers were not affected.
