6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 6,486 peer-reviewed studies on electromagnetic field health effects from 4 research libraries.

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Change of nitric oxide concentration in men exposed to a 1.5 T constant magnetic field

Sirmatel O, Sert C, Tümer C, Oztürk A, Bilgin M, Ziylan Z · 2007

Researchers measured nitric oxide production in 33 healthy young male volunteers aged 18 to 26 years old immediately after a 30-minute exposure to a 1.5 T magnetic field. A control group of 30 healthy male volunteers aged 19 to 26 years old was not exposed to the magnetic field, and their nitric oxide levels were also measured. Total nitrite concentration in post-exposure samples was found to be higher than in pre-exposure samples (P < .05).

Total antioxidant capacity, total oxidant status and oxidative stress index in the men exposed to 1.5 T static magnetic field.

Sirmatel O, Sert C, Sirmatel F, Selek S, Yokus B · 2007

Researchers investigated the effects of a 1.5 T static magnetic field, produced by an MRI apparatus, on oxidative stress markers in 33 male volunteers. Total antioxidant capacity showed a significant increase after exposure compared to before exposure (p < 0.05). Oxidative stress index and total oxidant status showed a significant decrease after exposure compared to before exposure (p < 0.01 for each). The researchers concluded that the 1.5 T static magnetic field produced a positive effect of decreasing oxidative stress in men following short-term exposure.

Oxidative Stress149 citations

Effects of magnetic field on the antioxidant enzyme activities of suspension-cultured tobacco cells

Sahebjamei H, Abdolmaleki P, Ghanati F · 2007

Researchers investigated the effects of static magnetic fields on antioxidant enzyme activities in suspension-cultured tobacco cells. Cells were exposed to static magnetic fields at 10 and 30 mT for 5 days, 5 hours each day, and compared with control cells. Superoxide dismutase activity increased with exposure, while catalase and ascorbate peroxidase activity decreased, and lipid peroxidation levels also increased.

Biophoton emission of MDCK cell with hydrogen peroxide and 60 Hz AC magnetic field.

Cheun BS, Yi SH, Baik KY, Lim JK, Yoo JS, Shin HW, Soh KS · 2007

Researchers studied biophoton emission from Madin-Darby canine kidney (MDCK) cells treated with hydrogen peroxide, with and without exposure to a 60 Hz AC magnetic field. Hydrogen peroxide increased biophoton emission from the cells, and the increase was dependent on the amount of hydrogen peroxide applied. When the 60 Hz AC magnetic field was applied, the decay of chemiluminescence intensity took a different path compared to cells not exposed to the field.

Affective response to 5 microT ELF magnetic field-induced physiological changes.

Stevens P · 2007

Researchers studied whether exposure to a 0–5 µT magnetic field at EEG alpha-band frequencies (8–12 Hz) would affect emotional state. Participants reported a change in emotional state following exposure, and a decrease in global field power was observed. The frontal alpha-asymmetry that would physiologically indicate a directly induced emotional state was absent, and researchers suggested that participant experiences were due to an interpretation of the effects of MF exposure.

Exposure to extremely low frequency magnetic fields enhances locomotor activity via activation of dopamine D1-like receptors in mice.

Shin EJ et al. · 2007

Researchers examined the role of dopaminergic receptors in behavioral changes induced by extremely low frequency magnetic fields (ELF-MF). Exposure to ELF-MF at 2.4 mT for 1 hour per day, for one or seven days, enhanced locomotor activity in a time-dependent manner. The results suggest that ELF-MF-induced behavioral responses are, at least in part, mediated by activation of dopamine D1-like receptors.

Influence of extremely low frequency magnetic fields on Ca2+ signaling and NMDA receptor functions in rat hippocampus

Manikonda PK et al. · 2007

Researchers exposed rats to 50 Hz magnetic fields at 50 and 100 μT intensities for 90 days and then examined hippocampal tissue. Compared to controls, ELF exposure was associated with increased intracellular calcium levels and changes in the activity of several calcium-related enzymes. Binding to NMDA receptors was also found to be decreased in exposed rats. The researchers suggested that perturbed neuronal functions caused by ELF exposure may involve altered calcium signaling contributing to aberrant NMDA receptor activities.

Acute exposure to a 50 Hz magnetic field impairs consolidation of spatial memory in rats

Jadidi M et al. · 2007

Researchers used a water maze to evaluate how magnetic field exposure affects consolidation and retrieval of spatial memory in rats. Exposure to a 50 Hz, 8 mT magnetic field for 20 minutes immediately after training impaired retention performance, but exposure at 2 mT did not. Exposure given shortly before retention testing had no effect on performance.

Exposure to an additional alternating magnetic field affects comb building by worker hornets.

Ishay JS et al. · 2007

Researchers kept Oriental hornet workers in an Artificial Breeding Box and exposed them to an AC magnetic field of a magnitude of B = 50-70 mGauss, comparing the combs they built with those from a control group exposed only to the natural terrestrial magnetic field. Exposed hornets built combs with a 35-55% smaller number of cells and fewer eggs, many deformed and imperfectly hexagonal cells, and more delicate and slender comb stems.

Fifty Hertz electromagnetic field exposure stimulates secretion of β-amyloid peptide in cultured human neuroglioma

Del Giudice E et al. · 2007

Researchers tested whether low-frequency electromagnetic field exposure could affect amyloidogenic processes in cultured cells. They exposed H4 neuroglioma cells that stably overexpress human mutant amyloid precursor protein to a 3.1 mT 50 Hz field. Overnight exposure significantly increased secretion of amyloid-beta peptide, including the isoform Aβ 1–42, without affecting cell survival.

Pulsed radio-frequency electromagnetic fields: dose-dependent effects on sleep, the sleep EEG and cognitive performance.

Regel SJ et al. · 2007

Researchers exposed the heads of 15 healthy male subjects for 30 min prior to sleep to a pulse-modulated EMF signal at different intensities or a sham condition, in a double-blind, crossover design. The active exposure levels used peak spatial specific absorption rates of 0.2 W kg–1 and 5 W kg–1. Sleep EEG analysis showed a dose-dependent increase of power in the spindle frequency range in non-REM sleep, while sleep architecture was not affected. Reaction speed slowed with increasing field intensity in the 1-back task, but accuracy in the CRT and N-back tasks was not affected in a dose-dependent manner.

Effects of GSM 1800 MHz on dendritic development of cultured hippocampal neurons.

Ning W, Xu SJ, Chiang H, Xu ZP, Zhou SY, Yang W, Luo JH · 2007

Researchers cultured hippocampal neurons from rats and exposed them to GSM 1800 MHz microwaves at either 2.4 or 0.8 W/kg for 15 minutes each day from DIV6 to DIV14. At 2.4 W/kg, the density and mobility of dendritic filopodia at DIV8 and the density of mature spines at DIV14 were significantly decreased, and the average length of dendrites per neuron at DIV10 and DIV14 was also decreased. Dendritic arborization was unaltered in the exposed neurons, and no significant changes were found in neurons exposed to 0.8 W/kg.

Mobile phone radiation and the developing brain: behavioral and morphological effects in juvenile rats.

Kumlin T et al. · 2007

Researchers exposed young male Wistar rats to a 900 MHz mobile phone signal for 2 h/day on 5 days/week. After 5 weeks of exposure at whole-body average specific energy absorption rates of 0.3 or 3.0 W/kg or sham exposure, rats were assessed for behavioral and morphological changes. No degenerative changes, dying neurons, or effects on blood-brain barrier leakage were detected, and no group differences appeared in the open-field, plus maze, or acoustic startle response tests. In the water maze test, significantly improved learning and memory were detected in rats exposed to RF fields.

Mobile phone 'talk-mode' signal delays EEG-determined sleep onset.

Hung CS, Anderson C, Horne JA, McEvoy P · 2007

Researchers exposed 10 healthy young adults to talk, listen, standby, or sham signal modes for 30 minutes, then gave them a 90-minute sleep opportunity. Sleep latency after talk mode was markedly and significantly delayed beyond listen and sham modes. This condition effect was also evident in 1–4 Hz EEG frontal power, a frequency range described as particularly sensitive to sleep onset. There was no condition effect for subjective sleepiness.

Effect of an acute 900 MHz GSM exposure on glia in the rat brain: A time-dependent study

Brillaud E, Piotrowski A, de Seze R · 2007

Researchers measured GFAP expression in rat brains 2, 3, 6, and 10 days after a single 15-minute 900 MHz GSM exposure at a brain averaged SAR of 6 W/kg. A statistically significant increase in GFAP stained surface area was observed 2 days after exposure in the frontal cortex and the caudate putamen. A smaller statistically significant increase was noted 3 days after exposure in those same areas and in the cerebellum cortex. The researchers concluded this was a temporary effect, probably due to a hypertrophy of glial cells, and noted that whether the effect could be harmful remains to be studied.

Studying gene expression profile of rat neuron exposed to 1800MHz radiofrequency electromagnetic fields with cDNA microassay.

Zhao R, Zhang S, Xu Z, Ju L, Lu D, Yao G. · 2007

Researchers investigated whether 1800 MHz radiofrequency electromagnetic fields could influence gene expression in rat neurons. Among 1200 candidate genes, 24 were up-regulated and 10 were down-regulated after 24 hours of intermittent exposure at a SAR of 2 W/kg. The researchers concluded that gene expression in rat neurons could be altered by exposure to radiofrequency electromagnetic fields under their experimental conditions.

Radiofrequency radiation (900 MHz) induces Egr-1 gene expression and affects cell-cycle control in human neuroblastoma cells.

Buttiglione M et al. · 2007

Researchers exposed human neuroblastoma SH-SY5Y cells to 900 MHz radiofrequency radiation at 1 W/kg to study effects on gene expression and cell-cycle control. Short-term exposures produced a transient increase in Egr-1 mRNA levels along with activation of the MAPK subtypes ERK1/2 and SAPK/JNK. Exposure had an anti-proliferative effect, and a significant G2-M cell-cycle arrest was observed, with signs of apoptosis appearing after 24 hours. A significant decrease in mRNA levels of Bcl-2 and survivin genes, both linked to signaling between G2-M arrest and apoptosis, was also observed.

Plasma concentrations of thyroxine in dairy cows exposed to 60 Hz electric and magnetic fields

Unknown authors · 2006

Two experiments were carried out to assess the effects of electric and magnetic fields on blood thyroxine in dairy cattle. In experiment 2, 16 nonlactating, nonpregnant, multiparous Holsteins were exposed to the same EMF with periods corresponding to one estrous cycle and blood samples were collected every other day, and the effect of period (P = .0009) and the treatment by days interaction (P = .0003) were statistically significant.

Sex and estrous cycle differences in the behavioral effects of high-strength static magnetic fields: role of ovarian steroids

Unknown authors · 2006

Rats were given 10-min access to a novel saccharin solution and then restrained within a 14-T magnet for 30 min. In experiment 1, males were compared with females across the estrous cycle after a single MF exposure. Females circled more and acquired a more persistent CTA than males; circling was highest on the day of estrus. In experiment 2, the effects of three MF exposures were compared among intact rats, ovariectomized females, and ovariectomized females with steroid replacement. Compared with intact rats, ovariectomy increased circling; estrogen replacement blocked the increase, and males acquired a stronger initial CTA but extinguished faster than intact or ovariectomized females.

Clastogenicity and aneuploidy in newborn and adult mice exposed to 50 Hz magnetic fields

Unknown authors · 2006

Researchers used the micronucleus test with CREST antibody staining to assess clastogenic and aneugenic effects of a 50 Hz, 650 muT magnetic field. Newborn mice were exposed during the entire 21-day intra-uterine period, and adult mice were exposed for the same duration. Newborn mice showed a significant increase in micronuclei frequencies, with most induced micronuclei being CREST-negative chromosome fragments. ELF exposure caused a two-fold increase in CREST-negative micronuclei and a four-fold increase in CREST-positive micronuclei in newborn mice. No significant effect was observed in exposed adult mice.

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