Janać B, Tovilović G, Tomić M, Prolić Z, Radenović L. · 2009
Researchers exposed adult Wistar rats continuously to an extremely low frequency magnetic field (50 Hz, 0.5 mT) for 1, 3, and 7 days. The study examined serotonin 5-HT(2A) receptors in the prefrontal cortex and dopamine D(1) and D(2) receptors in the striatum, considering their involvement in motor behavior regulation. Serotonin 5-HT(2A) receptor affinity decreased and density increased in the prefrontal cortex, with the affinity effect being most prominent after 7 days of exposure. Dopamine D(1) and D(2) receptors in the striatum showed no significant effect on either affinity or density.
Di Loreto S et al. · 2009
Researchers investigated the effects of exposures to two different 50 Hz sinusoidal ELF magnetic field intensities, 0.1 and 1 mT, on maturing rat cortical neurons. Exposure positively affected cell viability and reduced apoptotic death, with no significant effects on the main antioxidative defences. Linear regression analysis suggested a positive correlation between reduced glutathione and ROS levels in 1 mT magnetic-field-exposed cells. The researchers also observed brain-derived neurotrophic factor over-expression and interleukin 1β-dependent regulation of pro-survival signaling pathways following exposure.
Cvetkovic D, Cosic I. · 2009
Researchers tested whether a series of extremely low frequency magnetic field exposures at 50, 16.66, 13, 10, 8.33, and 4 Hz could alter relative power within corresponding brainwave bands. Thirty-three human subjects were tested under double-blind and counter-balanced conditions. Narrow alpha1 and alpha2 bands were significantly lower than control over temporal and parietal regions during the first exposure session, then significantly higher than control during the second session. The beta1 band showed a significant increase from before to after the 13 Hz first exposure session at the frontal region.
Coşkun S, Balabanli B, Canseven A, Seyhan N. · 2009
Researchers exposed adult guinea pigs to a continuous and intermittent 50 Hz, 1.5 mT magnetic field for 4 hours per day for 4 days. Intermittent magnetic field exposure was effective on plasma lipid peroxidation, while continuous magnetic field exposure was effective on plasma MPO activity and NO levels. Augmentation of lipid peroxidation was observed in liver tissue under both intermittent and continuous magnetic field exposures.
Cook CM, Saucier DM, Thomas AW, Prato FS. · 2009
Researchers exposed 32 human subjects to two different pulsed magnetic field sequences that differed in presentation rate, to examine effects on the alpha frequency of the human EEG. Alpha activity was lowered over occipital-parietal regions during Sequence 1 exposure, while alpha activity over the same regions was higher after Sequence 2 exposure. These effects occurred after approximately 5 minutes of pulsed magnetic field exposure.
Balassa T, Szemerszky R, Bárdos G. · 2009
Researchers exposed rats to a 50 Hz electromagnetic field and then tested situational and social anxiety as well as locomotor activity. The tests used included the elevated plus-maze, novel object exploration, social interaction, and territoriality assessments. The researchers found that the field parameters may cause discomfort and may influence behavior, but there was no verified effect on social and territorial behavior.
Wiholm C et al. · 2009
Researchers studied the effects of a 2 1/2 h RF exposure at 884 MHz on spatial memory and learning using a double-blind repeated measures design. The exposure was designed to mimic that experienced during a real-life mobile phone conversation, with an average peak spatial specific absorption rate of 1.4 W/kg. Results showed a significant RF exposure by group effect on distance traveled during the trials, with the symptomatic group improving their performance during RF exposure while there was no such effect in the non-symptomatic group.
Söderqvist F, Carlberg M, Hansson Mild K, Hardell L · 2009
Researchers exposed 41 volunteers to a 30 min GSM 890 MHz signal at an average specific energy absorption rate distribution of 1.0 W/kg in the temporal area of the head. S100B showed no statistically significant increase, while transthyretin showed a statistically significant increase in the final blood sample 60 min after the end of the provocation compared to the sample taken immediately after provocation (p = 0.02). The researchers noted that the clinical significance of this finding, if any, is unknown.
Sirav B, Seyhan N · 2009
Researchers investigated the effects of 900 and 1,800 MHz continuous-wave radio frequency radiation on blood-brain barrier permeability in rats. Twenty minutes of exposure at both frequencies increased blood-brain barrier permeability in male rats, while female rats showed no change. The researchers noted that the scientific evidence on radio frequency radiation safety or harm remains inconclusive.
Nittby H et al. · 2009
Rats were exposed in TEM-cells for 2 hours at non-thermal specific absorption rates of 0, 0.12, 1.2, 12, and 120 mW/kg, and albumin extravasation over the blood-brain barrier, neuronal albumin uptake, and neuronal damage were assessed. Albumin extravasation was enhanced in the mobile phone exposed rats compared to sham controls after a 7-day recovery period, with a significant result at the SAR value of 12 mW/kg. There was a low but significant correlation between the exposure level and the occurrence of focal albumin extravasation.
Naziroğlu M, Gümral N. · 2009
Researchers divided thirty rats into five groups to study the effects of 2.45 GHz electromagnetic radiation on the brain's antioxidant system and EEG records. Exposed rats received 2.45 GHz electromagnetic radiation for 60 minutes per day for 28 days, after which EEG records and brain cortex samples were collected. Brain cortex concentrations of vitamin A, vitamin C, and vitamin E were lower in the exposed group than in controls, though these concentrations were increased by selenium and L-carnitine supplementation. L-carnitine appeared to have a more protective effect on vitamin concentrations than selenium.
López-Martín E et al. · 2009
Researchers studied whether pulse-modulated GSM radiation had different effects on brain activity than an unmodulated signal of the same wavelength, and examined c-Fos expression in seizure-related brain circuits. Rats made seizure-prone with picrotoxin and then exposed to GSM radiation showed differences in clinical and EEG signs and in c-Fos expression compared with picrotoxin-treated rats exposed to unmodulated radiation. The most marked effects of GSM radiation on c-Fos expression in picrotoxin-treated rats were observed in limbic structures, olfactory cortex areas, subcortical areas, the dentate gyrus, and the central lateral nucleus of the thalamic intralaminar nucleus group. Neither radiation treatment caused tissue heating, so the researchers ruled out thermal effects.
Del Vecchio G et al. · 2009
de Tommaso M et al. · 2009
Researchers evaluated whether 900 MHz GSM phone exposure changed a brain electrical measure called the initial contingent negative variation (iCNV) in healthy volunteers using a double blind design. Ten healthy right-handed volunteers were evaluated, each recorded during a 10 min time interval in each of the three experimental conditions: a real emitting phone, a sham phone whose power was dissipated internally, and a phone switched off. The iCNV amplitude decreased and habituation increased during both the real and sham phone conditions compared with the off condition, with no significant prevalence of iCNV amplitude reduction on the left side, where the phones were located.
Dasdag S, Akdag MZ, Ulukaya E, Uzunlar AK, Ocak AR · 2009
The study used 31 Wistar Albino adult male rats, with the exposed group having their heads placed in a carousel and exposed to 900 MHz microwave radiation for 2 hours per day, 7 days a week, for 10 months. The apoptosis score in exposed rats was significantly lower than in both the sham group and the cage control group. Total antioxidant capacity and catalase were higher in the exposed group than in the sham group, while the oxidative stress index showed no significant difference between those groups. The protein p53 was not significantly changed by the exposure.
Daniels WM, Pitout IL, Afullo TJ, Mabandla MV · 2009
Researchers studied the effect of electromagnetic radiation in the mobile phone range on the behaviour of the rat. Behavioural, histological and biochemical tests were performed on exposed and unexposed male and female rats to examine learning and memory, emotional states and corticosterone levels. No significant differences were found in spatial memory or brain morphology between groups, but some exposed animals showed decreased locomotor activity, increased grooming and a tendency of increased basal corticosterone levels. The researchers suggested that EMR exposure may lead to abnormal brain functioning.
Curcio G et al. · 2009
Researchers used functional near-infrared spectroscopy (fNIRS) to measure frontal cortex oxygenation in eleven healthy volunteers during a 40-minute exposure to a GSM mobile phone signal. The study found a slight linear increase in deoxygenated hemoglobin over time during real exposure, but no other measure showed GSM exposure-dependent changes. The researchers noted that their results should be confirmed on a larger sample size and using a multichannel instrument that allows the investigation of a wider portion of the frontal cortex.
Bas O, Odaci E, Kaplan S, Acer N, Ucok K, Colakoglu S · 2009
Researchers investigated the number of pyramidal cells in the hippocampus of 16-week-old female rats following postnatal exposure to 900 MHz EMF. Rats in the EMF group were exposed to 900 MHz EMF for 1 hour per day for 28 days, with a SAR ranging from 0.016 (whole body) to 2 W/kg (locally in the head). Postnatal EMF exposure caused a significant decrease of the pyramidal cell number in the CA, and cell loss was also visible at qualitative observation.
Luukkonen J et al. · 2009
Researchers exposed human SH-SY5Y neuroblastoma cells to 872 MHz radiofrequency radiation at 5 W/kg for 1 hour, combined with menadione, a chemical that induces intracellular ROS production and DNA damage. Continuous-wave RF radiation increased DNA breakage compared to cells exposed only to menadione, and ROS levels were higher at 30 and 60 minutes after exposure ended. No effects of the GSM signal were seen on either ROS production or DNA damage.
Kesari KK, Behari J. · 2009
Researchers investigated the effects of 50-GHz microwave radiation on the brain of Wistar rats. The animals were exposed for 2 hours a day for 45 days continuously at a power level of 0.86 μW/cm2. Exposed rats showed DNA double-strand breaks and a significant decrease in GPx and SOD activity in brain cells, while catalase activity showed a significant increase compared with control. PKC decreased significantly in the whole brain and hippocampus of the exposed group.
Gajski G, Garaj-Vrhovac V. · 2009
Researchers investigated whether bee venom could protect against DNA damage caused by 915-MHz microwave radiation in Wistar rat lymphocytes. Whole blood lymphocytes were treated with 1 μg/mL bee venom before irradiation, and comet assays were used to assess basal and oxidative DNA damage. Bee venom showed a decrease in DNA damage compared with irradiated samples, and was found to have a radioprotective effect against both basal and oxidative DNA damage.
Del Vecchio G et al. · 2009
Researchers studied the effects of radiofrequency electromagnetic field exposure on neuronal maturation using two in vitro models: murine SN56 cholinergic cells and rat primary cortical neurons. Cells were exposed at 1 W/kg at 900 MHz GSM modulated, and neurite emission, outgrowth, and branching were examined at multiple time points. RF-EMF exposure reduced the number of neurites in both cell systems, and this reduction correlated with increased expression of beta-thymosin mRNA.
De Iuliis GN, Newey RJ, King BV, Aitken RJ. · 2009
Researchers exposed purified human spermatozoa in vitro to radio-frequency electromagnetic radiation tuned to 1.8 GHz across a range of specific absorption rates from 0.4 W/kg to 27.5 W/kg. As the SAR increased, sperm motility and vitality were significantly reduced, while mitochondrial reactive oxygen species generation and DNA fragmentation were significantly elevated (P<0.001). The researchers also observed highly significant relationships between SAR, the oxidative DNA damage biomarker 8-OH-dG, and DNA fragmentation after exposure.
Valbonesi P et al. · 2008
Researchers exposed human placental cells to cell phone radiation (1.8 GHz GSM signals) for one hour at levels twice the current safety limit to see if it would trigger cellular stress responses or DNA damage. The radiation exposure produced no detectable effects on stress proteins or DNA integrity, unlike positive control treatments that did cause measurable damage. This suggests that short-term exposure to this type of cell phone radiation may not immediately harm these particular cells.
Tokola K, Kurttio P, Salminen T, Auvinen A. · 2008
Researchers compared what 70 people said about their cell phone use in interviews versus actual usage data from phone companies. They found people consistently overestimated how much they used their phones, reporting about twice as much talk time as the records showed. This matters because most studies on cell phone health effects rely on people accurately remembering and reporting their usage, which this study shows they don't do well.
