Unknown authors · 2019
Researchers exposed honey bees for 17 hours to 100 μT or 1000 μT ELF EMFs or a sham control. A sting extension response assay measured aversive learning and an intruder assay measured aggression. Exposure to both field strengths reduced aversive learning performance by over 20%, and exposure to 100 μT increased aggression scores by 60%.
Unknown authors · 2019
Researchers induced traumatic brain injury in mice using a weight-drop method once daily for three days. Low-field magnetic stimulation was applied for 20 minutes once daily for four days immediately after each injury. Mice receiving the stimulation showed significant improvement in cognitive and motor tests including open field exploration, rotarod, and novel location recognition. The treatment increased cellular prion protein and decreased glial fibrillary acidic protein in cortical and hippocampal regions, and increased neuronal nuclei in the cortex. Proteins related to circadian rhythm decreased in stimulated mice compared with sham-treated mice.
Özgün A, Marote A, Behie LA, Salgado A, Garipcan B · 2019
Researchers examined the involvement of NMDA receptors in human neuronal differentiation under extremely low frequency magnetic field exposure. Human neural progenitor cells differentiated more efficiently under ELF MF exposure in vitro, shown by increased neuronal markers. Exposed cells showed higher intracellular calcium levels, evidenced by c-fos expression and more elongated mature neurites. Blocking NMDA receptors with memantine neutralized these effects.
Nishimura T, Tada H, Fukushima M · 2019
Lacroix A et al. · 2019
Thirty-nine participants completed two sessions 24 hours apart while learning a serial reaction time task with their right hand. In the first session, one group received stimulation over the left primary motor cortex, another over the right primary motor cortex, and a third received sham stimulation. Stimulation over the left primary motor cortex impaired online learning compared with the other groups, but did not impair offline learning or relearning.
Jakubowska M, Urban-Malinga B, Otremba Z, Andrulewicz E · 2019
Researchers exposed the polychaete Hediste diversicolor to a 50 Hz, 1 mT electromagnetic field typical of submarine cable environments. The worms showed no avoidance or attraction, but their burrowing activity increased, indicating a stimulating effect on bioturbation. Food consumption and respiration rates were unchanged, while ammonia excretion was significantly lower than in control animals kept in the geomagnetic field.
Unknown authors · 2019
Researchers used a lane change task and reaction time tests to assess driving performance and cognitive functions in 17 students exposed to a 350 μT static magnetic field. EEG recordings were taken during the experiment to monitor brain activity related to performance and cognition. The results showed that the static magnetic field did not considerably affect driving performance or cognitive functions, but a correlation was found between the EEG beta sub-band and reaction time.
Unknown authors · 2019
Researchers administered low-dose MK-801 (0.1 mg/kg) to male Wistar rats from postnatal day 6 to 10 and examined whether a static magnetic field altered its effects. Behavioral testing with Morris water maze, open field test, rotarod, and elevated plus maze was conducted on postnatal days P60-63 to assess learning, memory, locomotion, and anxiety. Low-dose MK-801 alone did not produce significant adverse effects, but combined with static magnetic field exposure it caused adverse effects on anxiety, locomotion, learning, and memory.
Unknown authors · 2019
The study aimed to examine microtubule polymerization and structural behavior in brain and sperm of rats exposed to a 50 Hz extremely low-frequency electromagnetic field. Twenties adult male rats were randomly divided into control and experimental groups, and semen and brain samples were split into four groups for microtubule polymerization analysis. There were no significant differences in testosterone, corticosterone, anxiety behavior, or sperm morphology between groups, but sperm viability, total motility, and progressive motility were significantly higher after exposure. Microtubule polymerization in sperm was significantly higher in the exposed group, and the secondary and tertiary structures of tubulin were significantly affected in both brain and sperm.
Ding H-M et al. · 2019
Researchers exposed adult male C57BL/6 mice to a 3-axis Helmholtz-coil hypomagnetic field simulation system for 72 hours. Short-term hypomagnetic field exposure induced a significant increase in anxiety-related behaviors. The findings provide important information for psychological intervention and health care of astronauts.
Unknown authors · 2019
Researchers measured occupational ELF-MF exposure in a power plant using the NIOSH manual. The median magnetic field at working sites was 0.85 µT. They assessed DNA single-strand breaks in 29 male utility workers and 28 male support personnel using the comet assay. Exposed workers showed significantly increased olive length, tail moment, and tail DNA percent. Induction of DNA damage was observed for the exposed workers compared with the controls.
Yao F et al. · 2019
Researchers randomly divided oligodendrocyte precursor cells into PEMF and non-PEMF groups and assessed differentiation markers at 3, 7, 14, and 21 days. PEMF exposure increased miR-219-5p expression and decreased Lingo1 expression during OPC differentiation. Under PEMF, miR-219-5p targeted Lingo1 and reversed the inhibitory effect of a miR-219-5p inhibitor on OPC differentiation. The authors concluded that PEMF promotes OPC differentiation by regulating miR-219-5p activity in vitro.
Sun L, Li X, Ma H, He R, Donkor PO · 2019
Unknown authors · 2019
Researchers exposed rainbow trout for 40 days and ragworm and Baltic clam for 12 days to a 50 Hz 1 mT electromagnetic field. They measured nuclear abnormalities in trout blood erythrocytes, ragworm coelomocytes, and clam gill cells. Exposure significantly increased micronuclei in trout and ragworm, nuclear buds on filament cells and blebbed nuclei only in clam, and nuclear buds in all species. The frequency of 8-shaped nuclei rose in trout and clam, apoptotic and binucleated cells rose only in clam, and ragworm showed no significant cytotoxic change.
Unknown authors · 2019
Researchers exposed primary cultured retinal pigment epithelial cells to 50 Hz extremely low frequency-pulsed electromagnetic fields for three days. They measured cell proliferation and apoptosis using ELISA and assessed gene expression of proangiogenic factors using RT-PCR. The exposure did not change cell proliferation or cell death, but it significantly increased the transcript levels of several proangiogenic genes including HIF-1α, VEGFA, VEGFR-2, CTGF, cathepsin D, TIMP-1, E2F3, MMP-2, and MMP-9.
Unknown authors · 2019
Researchers exposed Saccharomyces cerevisiae to a sinusoidal magnetic field (2.45 mT, 50 Hz, continuous) and a pulsed magnetic field (1.5 mT, 25 Hz, 8 h/day). Chronological aging was evaluated during 40 days. Survival was assayed by clonogenic assay and drop test, and cellular stability was studied by spontaneous mutation count and the index of respiratory competence. Pulsed magnetic field exposure accelerated chronological aging and decreased the spontaneous frequency of mitochondrial mutation, but did not alter the index of respiratory competence for either field type.
Unknown authors · 2019
Researchers exposed 80 adult male rats to ELF-EMFs at 1, 100, 500, and 2000 µT, 50 Hz, 2 hours daily for up to 60 days and immunized them on days 31, 44, and 58. Gene expression of c-Maf, STAT6, and RORα in the thymus did not change significantly at any flux density. In the spleen, RORα and c-Maf expression was significantly downregulated at 1 and 100 µT, while STAT6 expression decreased significantly only at 100 µT. The authors concluded that low magnetic flux densities of ELF-EMFs may reduce expression of these genes in the spleen.
Jin Y et al. · 2019
Researchers treated Arabidopsis seedlings with static magnetic fields of different intensities and directions relative to gravity. Root growth was significantly enhanced by 600 mT fields except when the field was oriented opposite to gravity, while 300 mT fields had no effect. The enhancement involved increased cell division in the root meristem and higher auxin levels regulated by PIN3 and AUX1 expression. The growth promotion was absent in pin3 and aux1 mutants and in the double cryptochrome mutant cry1 cry2. Transcriptomic analysis showed that 85% of genes down-regulated by the parallel magnetic field were enriched in plastid biological processes.
Dong D et al. · 2019
Researchers used a 16 T high static magnetic field generated from a superconducting magnet. They measured osteoclast formation, bone resorption, acting ring formation, messenger ribonucleic acid expression, and protein expression, as well as iron levels, mitochondrial protein, adenosine triphosphate, reactive oxygen species, malonaldehyde, and glutathione. The high static magnetic field significantly inhibited osteoclastic formation and resorption ability and reduced cellular iron content, and decreased mitochondrial concentration and oxidative stress levels. Mechanistically, the high static magnetic field markedly blocked the expression of osteoclast-associated transcription factors and osteoclast marker genes and inhibited iron absorption and iron storage-related protein expression.
Unknown authors · 2019
Exposure to each field increased early expression of IL-6, TGF-β, and iNOS and later induced MMP-2, MCP-1, and HO-1, which quickened wound healing. Electromagnetic field exposure also influenced the proliferation, migration, and metabolism of the fibroblasts compared with sham-exposed cells.
Unknown authors · 2019
The study aimed to evaluate the effect of extremely low frequency electromagnetic field treatment on the molecular mechanism of inflammatory cytokine activity in post-stroke patients. All patients received the same physical therapy program, and the ELF-EMF group also received ELF-EMF treatment. The researchers measured plasma levels of IL-1β, IL-2, IFN-γ, and TGF-β, and IL-1β mRNA expression. After ELF-EMF treatment, IL-1β plasma level, IL-1β mRNA expression, and IL-2 plasma level increased, while IFN-γ and TGF-β levels did not change. Further research is needed to explore this hypothesis.
Unknown authors · 2019
Baek S, Choi H, Park H, Cho B, Kim S, Kim J · 2019
Researchers found that a hypomagnetic field environment attenuates differentiation capacity and is detrimental to cell fate changes during in vitro differentiation of embryonic stem cells. Hypomagnetic field conditions cause abnormal DNA methylation through dysregulation of DNA methyltransferase3b expression, resulting in incomplete DNA methylation during differentiation. The results suggest that an appropriate electromagnetic field environment may be essential for favorable epigenetic remodeling during cell fate determination via differentiation.
Ahmadi-Zeidabadi, M., Z. · 2019
(VT, VO, AE, LE · 2019
Researchers exposed human ventricular cardiomyocytes to 50 Hz magnetic fields at 100 µT for 1 hour continuously or 75 minutes intermittently. They also exposed ten male Sprague-Dawley rats to 50 Hz magnetic fields at 100 µT for 7 days while another ten rats were sham exposed. Exposure did not induce DNA damage, cell cycle changes, or increased ROS levels, and no significant differences were found in p53 and Hsp70 expression between exposed and sham groups in vitro or in vivo.