3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 1,014 studies (Rodent Studies)

Do 100- and 500-μT ELF magnetic fields alter beta-amyloid protein, protein carbonyl and malondialdehyde in rat brains?

Akdag MZ, Dasdag S, Cakir DU, Yokus B, Kizil G, Kizil M. · 2013

Researchers exposed rats to magnetic fields at levels considered safe by current standards for 10 months. The exposure significantly increased two markers of brain cell damage and aging, suggesting that even "safe" magnetic field levels may cause harmful oxidative stress in brain tissue over time.

Effects of exposure to a 50 Hz sinusoidal magnetic field during the early adolescent period on spatial memory in mice.

Wang X et al. · 2013

Researchers exposed young adolescent mice to 50 Hz magnetic fields (the same frequency as power lines) for one hour daily during a critical brain development period. Surprisingly, the exposed mice showed improved spatial learning and memory compared to unexposed mice when tested in maze tasks. This unexpected finding suggests that magnetic field exposure during adolescence might enhance certain cognitive abilities, though the implications for human brain development remain unclear.

Chronic exposure to an extremely low‐frequency magnetic field induces depression‐like behavior and corticosterone secretion without enhancement of the hypothalamic–pituitary–adrenal axis in mice†

Kitaoka K, Kitamura M, Aoi S, Shimizu N, Yoshizaki K. · 2013

Researchers exposed mice to extremely low frequency magnetic fields (ELF-MF) at 3 milliTesla for 200 hours and measured their behavior and stress hormone levels. The exposed mice showed significantly more depression and anxiety-like behaviors, along with elevated levels of the stress hormone corticosterone. This suggests that chronic exposure to strong magnetic fields may affect mental health and stress response systems.

Exposure to extremely low-frequency electromagnetic fields modulates Na+ currents in rat cerebellar granule cells through increase of AA/PGE2 and EP receptor-mediated cAMP/PKA pathway.

He YL, Liu DD, Fang YJ, Zhan XQ, Yao JJ, Mei YA. · 2013

Chinese researchers exposed rat brain cells to power line-frequency electromagnetic fields for 10-60 minutes and found sodium channels increased activity by 30-125%. Since sodium channels control nerve signals, this suggests EMF exposure can directly alter how brain cells communicate with each other.

Increased vascular permeability in the circumventricular organs of adult rat brain due to stimulation by extremely low frequency magnetic fields

Gutiérrez-Mercado YK et al. · 2013

Researchers exposed rats to extremely low frequency magnetic fields (120 Hz at 0.66 mT) and found that these fields increased blood vessel permeability in specific brain regions called circumventricular organs. The magnetic field exposure caused blood vessels to dilate and become more permeable to substances that normally can't cross into brain tissue. This suggests that ELF magnetic fields can compromise the brain's protective blood barrier system.

The preventive effect of lotus seedpod procyanidins on cognitive impairment and oxidative damage induced by extremely low frequency electromagnetic field exposure

Duan Y, Wang Z, Zhang H, He Y, Lu R, Zhang R, Sun G, Sun X. · 2013

Researchers exposed mice to 50 Hz magnetic fields (8 mT) for 28 days and found significant damage to learning and memory abilities, plus harmful oxidative stress in brain tissue. When mice were also given lotus seedpod extract, these negative effects were largely prevented. This suggests that extremely low frequency electromagnetic fields can damage brain function through oxidative stress mechanisms.

Effects of aluminum and extremely low frequency electromagnetic radiation on oxidative stress and memory in brain of mice.

Deng Y, Zhang Y, Jia S, Liu J, Liu Y, Xu W, Liu L. · 2013

Researchers exposed mice to power line frequency magnetic fields for 8 weeks and found significant brain damage including memory loss, brain cell death, and cellular stress markers. While exposure levels exceeded typical household amounts, the study demonstrates these electromagnetic fields can directly harm brain tissue.

Changes in synaptic efficacy in rat brain slices following extremely low-frequency magnetic field exposure at embryonic and early postnatal age

Balassa T et al. · 2013

Researchers exposed pregnant and newborn rats to 50 Hz magnetic fields (household electricity frequency) during brain development. The exposure altered how brain cells communicate, increasing electrical activity but impairing the brain's ability to form new memories and connections during critical developmental periods.

Fifty-Hertz electromagnetic fields facilitate the induction of rat bone mesenchymal stromal cells to differentiate into functional neurons

Bai WF, Xu WC, Feng Y, Huang H, Li XP, Deng CY, Zhang MS. · 2013

Chinese researchers exposed stem cells from rat bone marrow to 50 Hz magnetic fields (the same frequency as power lines) for one hour daily over 12 days. The electromagnetic field exposure helped these stem cells transform into functional brain neurons that could form connections and transmit electrical signals. This suggests that power-frequency magnetic fields might have therapeutic potential for treating nervous system diseases through stem cell therapy.

Impairment of long-term potentiation induction is essential for the disruption of spatial memory after microwave exposure

Wang H et al. · 2013

Researchers exposed rats to microwave radiation at 2.856 GHz for 6 minutes and tested their memory using a water maze. Rats exposed to higher power levels (10 and 50 mW/cm²) showed significant memory problems and brain damage, including damaged brain cells and disrupted connections between neurons. The study reveals that microwave exposure can impair the brain's ability to form memories by damaging the hippocampus, the brain region critical for learning.

Spatial memory and learning performance and its relationship to protein synthesis of Swiss albino mice exposed to 10 GHz microwaves

Sharma A, Sisodia R, Bhatnagar D, Saxena VK · 2013

Researchers exposed mice to 10 GHz microwave radiation for two hours daily over 30 days, then tested their memory using a water maze. Exposed mice took significantly longer to learn and remember locations, with reduced brain protein levels, suggesting microwave exposure may impair learning and memory.

Transient and cumulative memory impairments induced by GSM 1.8 GHz cell phone signal in a mouse model

Ntzouni MP et al. · 2013

Researchers exposed mice to cell phone radiation (GSM 1.8 GHz) for 90 minutes daily to test effects on memory. After weeks of exposure, the mice showed significant problems with both spatial memory (remembering locations) and non-spatial memory (recognizing objects). These memory problems persisted for two weeks after radiation stopped but fully recovered after a month, suggesting the brain can repair this type of damage over time.

Effects of long-term electromagnetic field exposure on spatial learning and memory in rats.

Hao D, Yang L, Chen S, Tong J, Tian Y, Su B, Wu S, Zeng Y · 2013

Researchers exposed rats to 916 MHz radiofrequency radiation (similar to cell phone signals) for 6 hours daily over 10 weeks and tested their ability to navigate a maze to find food. The exposed rats showed significantly impaired learning and memory during weeks 4-5, taking longer to complete the maze and making more errors, while brain recordings revealed disrupted neuron firing patterns throughout the study.

Maternal mobile phone exposure adversely affects the electrophysiological properties of Purkinje neurons in rat offspring

Haghani M, Shabani M, Moazzami K · 2013

Pregnant rats exposed to cell phone radiation (900 MHz) for six hours daily produced offspring with altered brain function. While the young rats behaved normally, their Purkinje neurons (cells controlling movement and learning) showed reduced electrical activity, suggesting prenatal exposure affects developing brain circuits.

Pyramidal Cell Loss in the Cornu Ammonis of 32-day-old Female Rats Following Exposure to a 900 Megahertz Electromagnetic Field During Prenatal Days 13–21.

Baş O et al. · 2013

Researchers exposed pregnant rats to cell phone frequency radiation (900 MHz) for one hour daily during a critical brain development period and examined their female offspring at 32 days old. They found significant loss of pyramidal neurons in the hippocampus, a brain region crucial for learning and memory. This suggests that prenatal EMF exposure during critical development windows may cause lasting brain damage that persists into later life.

Whole body exposure to 2.4 GHz WIFI signals: Effects on cognitive impairment in adult triple transgenic mouse models of Alzheimer's disease (3xTg-AD)

Banaceur S, Banasr S, Sakly M, Abdelmelek H · 2013

Researchers exposed mice genetically programmed to develop Alzheimer's-like symptoms to WiFi signals (2.4 GHz) for 2 hours daily over one month. Surprisingly, they found the WiFi exposure actually improved cognitive performance in the Alzheimer's mice compared to unexposed controls. This unexpected result suggests radiofrequency radiation might have some protective effects on brain function in certain disease states.

The effect of pulsed electromagnetic radiation from mobile phone on the levels of monoamine neurotransmitters in four different areas of rat brain

Aboul Ezz HS, Khadrawy YA, Ahmed NA, Radwan NM, El Bakry MM · 2013

Researchers exposed rats to cell phone radiation (1800 MHz) for 24 hours daily over 1-4 months and measured key brain chemicals called neurotransmitters in four brain regions. The radiation significantly altered levels of dopamine, norepinephrine, and serotonin - chemicals that control mood, memory, learning, and stress responses. These changes persisted even after radiation exposure stopped, suggesting that chronic cell phone use may disrupt normal brain chemistry.

Reproductive HealthNo Effects Found

Effect of in utero wi-fi exposure on the pre- and postnatal development of rats.

Poulletier de Gannes F et al. · 2012

French researchers exposed pregnant rats to Wi-Fi signals (2.45 GHz) for 2 hours daily during pregnancy to test whether this radiation could harm developing babies. They found no birth defects, developmental problems, or other harmful effects in the rat pups, even at the highest exposure level tested (4 W/kg). This study suggests that Wi-Fi exposure during pregnancy may not cause developmental harm at levels tested.

Brain & Nervous SystemNo Effects Found

Exposure to 1950-MHz TD-SCDMA Electromagnetic Fields Affects the Apoptosis of Astrocytes via Caspase-3-Dependent Pathway.

Liu YX et al. · 2012

Chinese researchers exposed brain cells (astrocytes) to cell phone radiation at 1950 MHz for up to 48 hours and found that prolonged exposure damaged the cells' power centers (mitochondria) and triggered programmed cell death. While the radiation didn't promote tumor formation, it caused significant cellular damage through a specific biological pathway involving proteins that control cell death. This suggests that continuous exposure to cell phone frequencies may harm healthy brain cells even when it doesn't directly cause cancer.

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