3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 1,014 studies (Rodent Studies)

Deficits in Water Maze Performance and Oxidative Stress in the Hippocampus and Striatum Induced by Extremely Low Frequency Magnetic Field Exposure

Cui Y, Ge Z, Rizak JD, Zhai C, Zhou Z, Gong S, Che Y. · 2012

Researchers exposed mice to power line frequency magnetic fields for 4 hours daily over 12 weeks. The exposed mice showed impaired learning and memory abilities, plus brain damage from oxidative stress. This suggests household electrical fields may affect cognitive function.

Short-term exposure to 50 Hz ELF-EMF alters the cisplatin-induced oxidative response in AT478 murine squamous cell carcinoma cells.

Bułdak RJ et al. · 2012

Researchers exposed mouse cancer cells to 50 Hz electromagnetic fields for 16 minutes, with and without chemotherapy drug cisplatin. The electromagnetic fields caused mild DNA damage alone but surprisingly reduced cisplatin's toxic effects when combined, showing EMF interactions depend on other environmental factors present.

The effect of different strengths of extremely low-frequency electric fields on antioxidant status, lipid peroxidation, and visual evoked potentials.

Akpinar D, Ozturk N, Ozen S, Agar A, Yargicoglu P · 2012

Researchers exposed rats to extremely low-frequency electric fields at two different strengths for one hour daily over 14 days, then measured brain and eye damage. They found that both exposure levels significantly increased oxidative stress (cellular damage from harmful molecules) and impaired visual processing in the brain. The higher exposure level caused more damage, suggesting a dose-response relationship between electric field strength and biological harm.

Neuroprotective effects of extremely low-frequency electromagnetic fields on a Huntington's disease rat model: effects on neurotrophic factors and neuronal density.

Tasset I et al. · 2012

Researchers exposed rats with a Huntington's disease-like condition to 60 Hz electromagnetic fields at 0.7 milliTesla (similar to standing very close to power lines) for 4 hours daily over 21 days. The electromagnetic field exposure significantly protected brain cells from damage, reduced harmful oxidative stress, and preserved neurons that would otherwise die from the disease. This suggests that certain types of electromagnetic fields might have therapeutic potential for neurodegenerative diseases.

Subacute exposure to 50-Hz electromagnetic fields affect prenatal and neonatal mice’s motor coordination.

Sakhnini L, Al Ali H, Al Qassab N, Al Arab E, Kamal A. · 2012

Researchers exposed pregnant mice to power line frequency electromagnetic fields for seven days, then tested their babies' motor skills. Mice exposed in the womb showed significant learning deficits compared to unexposed mice, suggesting developing brains are particularly vulnerable to EMF during pregnancy.

Neurodevelopmental anomalies of the hippocampus in rats exposed to weak intensity complex magnetic fields throughout gestation.

Fournier NM, Mach QH, Whissell PD, Persinger MA. · 2012

Researchers exposed pregnant rats to extremely weak magnetic fields (similar to power line levels) throughout pregnancy and found that specific exposure levels caused permanent brain damage in the offspring. The baby rats exposed to low-intensity fields (30-50 nT) developed smaller hippocampus regions and showed impaired learning abilities as adults. Interestingly, both weaker and stronger magnetic field exposures didn't cause these problems, suggesting a narrow 'danger zone' of exposure intensity.

Deficits in water maze performance and oxidative stress in the hippocampus and striatum induced by extremely low frequency magnetic field exposure.

Cui Y, Ge Z, Rizak JD, Zhai C, Zhou Z, Gong S, Che Y. · 2012

Researchers exposed mice to extremely low frequency magnetic fields (the type emitted by power lines and electrical devices) for 4 hours daily and tested their learning abilities. The exposed mice showed significant impairments in both spatial memory and habit formation, along with increased oxidative stress (cellular damage) in key brain regions responsible for learning and memory.

The effect of different strengths of extremely low-frequency electric fields on antioxidant status, lipid peroxidation, and visual evoked potentials.

Akpinar D, Ozturk N, Ozen S, Agar A, Yargicoglu P. · 2012

Researchers exposed rats to extremely low-frequency electric fields (the type generated by power lines) for one hour daily over two weeks. The exposed animals showed significant damage to brain and retinal tissue, including increased oxidative stress (cellular damage from free radicals) and disrupted visual processing. This suggests that even brief daily exposures to electric fields can harm the nervous system and vision.

Exposure to 2.45 GHz electromagnetic fields elicits an HSP-related stress response in rat hippocampus.

Yang XS, He GL, Hao YT, Xiao Y, Chen CH, Zhang GB, Yu ZP. · 2012

Researchers exposed rats to WiFi-frequency radiation (2.45 GHz) for 20 minutes and found it triggered stress responses in brain cells. The radiation caused neurons in the hippocampus to produce heat shock proteins, indicating cellular damage in the brain region responsible for memory and learning.

The effect of melatonin on body mass and behaviour of rats during an exposure to microwave radiation from mobile phone.

Sokolovic D et al. · 2012

Researchers exposed rats to mobile phone radiation for 4 hours daily over 60 days and found the animals lost significant body weight and developed anxiety-like behaviors including agitation and irritability. When rats were given melatonin (a natural hormone) along with the radiation exposure, these negative effects were largely prevented, suggesting melatonin may offer protective benefits against microwave radiation damage.

Melatonin modulates wireless (2.45 GHz)-induced oxidative injury through TRPM2 and voltage gated Ca(2+) channels in brain and dorsal root ganglion in rat.

Nazıroğlu M et al. · 2012

Researchers exposed rats to 2.45 GHz radiation (the same frequency used in WiFi and microwave ovens) for one hour daily over 30 days and found it caused brain damage including increased calcium levels in neurons, oxidative stress, and abnormal brain wave patterns. However, when rats were given melatonin supplements, these harmful effects were significantly reduced, suggesting melatonin may protect against WiFi radiation damage to the brain and nervous system.

Calcium-binding proteins and GFAP immunoreactivity alterations in murine hippocampus after 1 month of exposure to 835 MHz radiofrequency at SAR values of 1.6 and 4.0 W/kg

Maskey D, Kim HJ, Kim HG, Kim MJ. · 2012

Researchers exposed mice to cell phone-level radiofrequency radiation (835 MHz) for one month at power levels similar to what phones emit during calls. They found significant damage to brain cells in the hippocampus, the brain region critical for memory and learning, including loss of protective proteins and signs of brain injury that worsened at higher exposure levels.

Glucose administration attenuates spatial memory deficits induced by chronic low-power-density microwave exposure

Lu Y et al. · 2012

Researchers exposed rats to 2.45 GHz microwave radiation (the same frequency used by WiFi and microwave ovens) for 3 hours daily over 30 days at very low power levels. The radiation caused significant memory and learning problems, and the rats' brain cells had trouble absorbing glucose, which is essential for brain function. However, when researchers gave the rats extra glucose, it reversed the memory problems.

The genotoxic effect of radiofrequency waves on mouse brain.

Karaca E et al. · 2012

Turkish researchers exposed mouse brain cells to radiofrequency radiation at 10.715 GHz (similar to cell phone frequencies) for 6 hours daily over 3 days. They found an 11-fold increase in DNA damage markers and significant changes in gene expression related to cell death. This suggests that RF radiation at levels comparable to wireless devices can directly damage brain cell DNA and disrupt normal cellular functions.

Brain proteome response following whole body exposure of mice to mobile phone or wireless DECT base radiation

Fragopoulou AF et al. · 2012

Researchers exposed mice to mobile phone and cordless phone radiation for 8 months and examined brain tissue for protein changes. They found that both radiation sources significantly altered 143 different proteins in brain regions, including proteins involved in brain function, stress response, and cell structure. These protein changes may explain symptoms like headaches, memory problems, and sleep disturbances reported by people with long-term phone use.

Effects of 900 MHz radiofrequency on corticosterone, emotional memory and neuroinflammation in middle-aged rats

Bouji M, Lecomte A, Hode Y, de Seze R, Villégier AS · 2012

French researchers exposed young and middle-aged rats to 15 minutes of cell phone radiation (900 MHz) at high levels to study brain and stress responses. They found that middle-aged rats showed increased brain inflammation and enhanced emotional memory, while young rats had elevated stress hormone levels. The study reveals that age affects how the brain responds to radiofrequency exposure, with different vulnerabilities at different life stages.

Suppressive effect of electromagnetic field on analgesic activity of tramadol in rats

Bodera P et al. · 2012

Polish researchers exposed rats to cell phone-frequency electromagnetic fields (1500 MHz and 1800 MHz) for 15 minutes and tested how well the painkiller tramadol worked afterward. While the EMF exposure alone didn't change pain sensitivity, it significantly reduced tramadol's pain-relieving effects when the two were combined. This suggests that EMF exposure from devices like cell phones might interfere with how certain medications work in the body.

Fetal Radiofrequency Radiation Exposure From 800-1900 Mhz-Rated Cellular Telephones Affects Neurodevelopment and Behavior in Mice

Aldad TS, Gan G, Gao XB, Taylor HS · 2012

Researchers exposed pregnant mice to radiofrequency radiation from cell phones (at levels similar to human exposure) throughout pregnancy and then tested the offspring's behavior and brain function. The exposed mice showed hyperactivity and memory problems as adults, along with measurable changes in brain cell communication in the prefrontal cortex. This study provides the first direct experimental evidence that prenatal cell phone radiation exposure can alter brain development and behavior.

Immune SystemNo Effects Found

Early life exposure to 2.45GHz WiFi-like signals: effects on development and maturation of the immune system

Sambucci M et al. · 2011

Italian researchers exposed newborn mice to WiFi-like signals (2.45 GHz) for 5 weeks during early development to see if young immune systems are more vulnerable to wireless radiation. They found essentially no effects on immune system development at either low (0.08 W/kg) or high (4 W/kg) exposure levels, with only one minor change in male mice at the higher level. The study suggests that developing immune systems may not be as sensitive to WiFi radiation as some have theorized.

Reproductive HealthNo Effects Found

The effects of simultaneous combined exposure to CDMA and WCDMA electromagnetic fields on rat testicular function.

Lee HJ et al. · 2011

Researchers exposed male rats to combined cell phone signals (CDMA and WCDMA) at very high levels for 12 weeks to study effects on sperm production and reproductive health. The study found no measurable harm to sperm count, testosterone levels, or testicular function even at radiation levels twice the current safety limits. This suggests that typical cell phone use may not directly damage male fertility through electromagnetic field exposure.

Cancer & TumorsNo Effects Found

Lymphoma development of simultaneously combined exposure to two radiofrequency signals in AKR/J mice.

Lee HJ et al. · 2011

Researchers exposed mice genetically prone to lymphoma to combined cell phone signals (CDMA and WCDMA) for 45 minutes daily over 42 weeks at high exposure levels (4.0 W/kg total). The study found no difference in lymphoma development between exposed and unexposed mice, though there was an inconsistent pattern of brain metastasis in some exposed animals.

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