Li H et al. · 2014
Researchers exposed Wistar rats to 2.856 GHz microwaves at power densities of 5, 10, 20, or 30 mW/cm2 for 6 minutes three times a week for up to 6 weeks. Spatial learning and memory, hippocampus structure, brain electrical activity, and neurotransmitter levels were assessed at different time points after the last exposure. The study found dose-dependent memory deficits alongside inhibition of brain electrical activity, hippocampus neuron degeneration, and neurotransmitter disturbances. The researchers suggested that the serotonin system may be involved in the cognitive deficits seen after long-term microwave exposure.
Jung IS, Kim HJ, Noh R, Kim SC, Kim CW. · 2014
Researchers investigated how extremely low frequency magnetic fields affect nerve-growth-factor-induced neuronal differentiation of PC12 cells using proteomic methods. After 5 days of exposure at 50 Hz and 1 mT, neurite length and the number of neurite-bearing cells increased, while proliferation activity decreased. Six proteins were found to be differentially expressed between exposed and unexposed NGF-treated cells, including peripherin, VGF8a, HSP72-psI, LMW-PTP/ACP1, TUBA1A, and OPA1L.
Ghazizadeh V, Nazıroğlu M · 2014
Chen C et al. · 2014
Researchers exposed embryonic neural stem cells (eNSCs) to 1800 MHz radiofrequency electromagnetic fields at SAR values of 1, 2, and 4 W/kg for 1, 2, and 3 days. RF-EMF exposure did not influence eNSC apoptosis, proliferation, cell cycle, or the ratio of differentiated neurons and astrocytes. However, neurite outgrowth of eNSC-derived neurons was inhibited after 4 W/kg RF-EMF exposure for 3 days. The mRNA and protein expression of proneural genes Ngn1 and NeuroD were decreased after RF-EMF exposure, while expression of their inhibitor Hes1 was upregulated.
Unknown authors · 2013
Unknown authors · 2013
The study investigated HSP70 responses in transfected rat primary fibroblast cells exposed to 10 Hz electric fields at intensities of 20–500 V/m. Low frequency electric fields induced HSP70 heat shock expression, with peak responses at 8 hours after a 2 hour exposure. The approximate threefold increase was substantially lower than that from thermal stimulation, raising questions about clinical utility.
Simon D et al. · 2013
Researchers exposed reconstructed epidermis models with and without melanocytes to 900 MHz GSM radiation at 2 mW/g for 6 hours. No changes were observed in epidermal architecture, epidermal markers, apoptotic cells, p53 induction, melanocyte location, dendricity, or melanin transfer after exposure. Loricrin and cytokeratin 14 decreased significantly at 6 hours, but all marker levels increased at 24 hours compared to 6 hours, alongside decreased 20S proteasome activity. The presence or absence of melanocytes did not affect the response of the reconstructed epidermis to exposure.
Ketabi N, Mobasheri H, Faraji-Dana R. · 2013
Researchers investigated the effects of ultra high frequency nonionizing electromagnetic fields on the channel activities of the nanopore forming protein OmpF porin. Using the voltage clamp technique on an artificial bilayer, they exposed the pore to electromagnetic fields at 910 to 990 MHz and found that the frequency of channel gating and voltage sensitivity increased, while conductance remained unchanged. No changes in membrane capacitance or permeability were identified, and the energy transferred to nano-environments was estimated to address possible thermal effects.
Gurbuz N, Sirav B, Colbay M, Yetkin I, Seyhan N. · 2013
Researchers exposed male Wistar albino rats to 1800 MHz or 2100 MHz radiofrequency radiation for 30 min per day, 6 days per week, for either a month or two months. They measured micronucleus frequency in exfoliated bladder cells as an indicator of genotoxic damage. No significant differences in micronucleus frequency were found between any exposed group and its corresponding control group, nor between the two 2100 MHz exposure durations.
Waldmann P et al. · 2013
Researchers investigated whether GSM 1,800 MHz radiofrequency fields cause genotoxic effects in human lymphocytes. Blood from 20 healthy volunteers was exposed to three specific absorption rates of 0.2, 2, and 10 W/kg and sham for 28 hours. Four genotoxicity tests were conducted, including chromosome aberration, micronucleus, sister chromatid exchange, and comet assays. None of the nine endpoints showed a significant and reproducible exposure effect across the three analyzing laboratories. Positive controls showed highly significant differences from sham exposures, validating the study methods.
Akdag MZ et al. · 2013
No significant differences were found in reproductive or oxidative stress parameters between sham and exposed groups. The 500 μT exposure increased the final apoptosis score compared with sham, whereas the 100 μT exposure did not.
Gavoçi E et al. · 2013
Researchers studied the effect of static and alternating extremely low frequency magnetic fields tuned to resonance conditions for potassium on TEA-sensitive voltage-dependent outward potassium currents in the human neuroblastoma BE(2)C cell line. Currents were measured using whole-cell patch clamp before, during, and after exposure. No significant changes in potassium current density were found. The study did not confirm the IPR hypothesis for these currents under the experimental conditions.
Azanza MJ et al. · 2013
Talei D, Valdiani A, Maziah M, Mohsenkhah M · 2013
Researchers analyzed the germination rate, germination percentage, and mean germination time of MR 219 rice seeds exposed to 2450 MHz microwave frequency for one, four, seven, and ten hours. Exposure for 10 hours resulted in the highest germination percentage, reaching 100% after three days with a mean germination time of 2.1 days. Other exposure times produced germination percentages ranging from 93% to 98%. Ten-hour exposure for six days significantly improved primary shoot and root length.
Sefidbakht Y et al. · 2013
Researchers used a rectangular waveguide system to expose luciferase to 940 MHz electromagnetic fields. Exposed luciferase showed significantly higher activity and smaller hydrodynamic radii than unexposed samples. Exposed samples also had less tendency to form aggregates. Dielectric measurements indicated changes related to disaggregation potency.
Pesnya DS, Romanovsky AV. · 2013
Nasri K, Daghfous D, Landoulsi A. · 2013
The study evaluated the effects of sub-lethal microwave radiation on Salmonella typhimurium. The bacteria were exposed to a dose of 3600 J delivered as a 40-second exposure at 90 W. Exposure significantly inhibited cellular growth. The treatment increased the effectiveness of most tested antibiotics, with exposed bacteria showing new or improved sensitivity. Gas chromatography analysis showed an increase in unsaturated fatty acids, and the bacteria became more sensitive to sodium deoxycholate and released more extracellular proteins, indicating membrane weakening.
Meo SA, Al Rubeaan K · 2013
The study aimed to determine the effects of mobile phone radiation on fasting blood glucose in Wistar Albino rats. Rats exposed for more than 15 minutes per day showed significantly higher fasting blood glucose and serum insulin than controls. HOMA-IR was significantly increased in the 15-30 and 46-60 minute per day groups compared with controls.
Loos N et al. · 2013
Koca O et al. · 2013
Twenty-one male Albino rats were divided into three groups of seven rats each. Group 1 was exposed to a Philips Genie 900 cell phone in speech mode for 8 hours per day for 20 days, and Group 2 was exposed for 20 days with kidneys removed after a 20-day interval. Light microscopic examination showed kidney tissue damage in exposed groups with mean severity scores significantly higher than controls.
Kao HK, Li Q, Flynn B, Qiao X, Ruberti JW, Murphy GF, Guo L. · 2013
Researchers exposed wounded diabetic mice to pulsed radiofrequency energy and assessed wound closure, cell proliferation, and gene expression. Pulsed radiofrequency energy increased dermal cell proliferation and collagen synthesis in the wounds. However, CD31 density and expression of vascular endothelial growth factor and basic fibroblast growth factor did not differ significantly between treated and sham groups. In fibroblast cultures, pulsed radiofrequency energy increased gelation time compared to sham exposure.
Cervellati F et al. · 2013
Liu C et al. · 2013
Ozorak A et al. · 2013
Kidney and testis samples were collected from decapitated rats during the fourth, fifth, and sixth weeks. In the fourth week, lipid peroxidation in kidney and testis and copper, zinc, GSH, GSH-Px, and TAS in kidney decreased, while iron in kidney and vitamin A and vitamin E in testis increased in exposed groups. In the fifth week, iron, vitamin A, and β-carotene in kidney increased, while GSH and TAS decreased in exposed groups. In the sixth week, iron concentrations in kidney and lipid peroxidation in kidney and testis increased, while copper, TAS, and GSH concentrations decreased in exposed groups.
Jelodar G, Akbari A, Nazifi S. · 2013
Researchers exposed adult male Sprague-Dawley rats to 900 MHz radiofrequency waves daily for 45 days and measured antioxidant enzymes and malondialdehyde in eye tissue. Radiofrequency wave exposure decreased glutathione peroxidase, superoxide dismutase, and catalase activity and increased malondialdehyde compared with controls. Vitamin C supplementation at 200 mg/kg per day improved antioxidant enzyme activity and reduced malondialdehyde compared with the test group.
