Zhang J, Ding C, Meng X, Shang P · 2018
Researchers studied whether nitric oxide modulates the responses of osteoclast formation to static magnetic fields. Field strengths of 500 nT (hypomagnetic field), 0.2 T (moderate static magnetic field), and 16 T (high static magnetic field) were utilized as treatment. At 16 T, osteoclast formation was markedly decreased and nitric oxide synthase activity was enhanced, producing a high level of NO. At 500 nT and 0.2 T, osteoclast formation increased alongside decreased NOS activity and NO production.
Sun Y, Shi Z, Wang Y, Tang C, Liao Y, Yang C, Cai P · 2018
Researchers exposed Caenorhabditis elegans to 50 Hz, 3 mT extremely low-frequency electromagnetic fields from the egg stage until the fourth larva stage. Reactive oxygen species levels were significantly elevated and total antioxidant capacity was significantly depressed in the exposed worms. The TCA cycle enzyme fumarase showed decreased expression, while arachidonic acid, prostaglandin E2, and prostaglandin E2 synthase all showed increased levels in exposed worms.
Sun L, Chen L, Bai L, Xia Y, Yang X, Jiang W, Sun W. · 2018
Researchers exposed human amnion epithelial (FL) cells to a 50-Hz magnetic field and investigated the role of reactive oxygen species (ROS) in magnetic-field-induced clustering of epidermal growth factor receptor (EGFR). When cells were pretreated with ROS scavengers NAC or PDTC before exposure, both the ROS-related effects and the EGFR clustering were inhibited. The researchers concluded that ROS mediates magnetic-field-induced EGFR clustering via ASMase activation.
Shokrollahi S, Ghanati F, Sajedi RH, Sharifi M · 2018
Researchers exposed soybean plants to static magnetic fields of 0, 20, and 30 mT for 5 days at 5 hours each day, examining ferrous content and the gene expression and activity of ferritin and catalase. At 20 mT, gene expression of the iron transporter, ferrous content, hydrogen peroxide content, and ferritin and catalase gene expression, content, and activity all decreased. Opposite responses were observed under 30 mT treatments. The researchers also evaluated purified ferritin and apoferritin from horse spleen and catalase from bovine liver under the static magnetic field, finding that tertiary structure, size, and activity were altered, while secondary structure was not influenced.
Seif F, Bayatiani MR, Ansarihadipour H, Habibi G, Sadelaji S · 2018
Researchers divided adult male rats into three groups: a control group, a group exposed to extremely low-frequency magnetic fields (ELFMF), and a group given Myrtus communis extract before ELFMF exposure. The magnetic field was set at 0.7 mT and 50 Hz, applied for two hours a day for one month. ELFMF exposure decreased plasma antioxidant power and significantly increased markers of oxidative damage, including protein carbonyl, methemoglobin, and hemichrome concentrations. Administration of M. communis extract increased antioxidant power and decreased plasma protein carbonyl, methemoglobin, and hemichrome concentrations.
Mohammadi F, Ghanati F, Sharifi M, Chashmi NA · 2018
Exposure to the static magnetic field delayed the G1 to S transition in the cell cycle, accompanied by a decrease in cyclin-dependent kinase A and D-type cyclin. The static magnetic field also increased levels of nitric oxide, hydrogen peroxide, and salicylic acid compared to the control group.
Medina-Fernandez FJ et al. · 2018
Researchers studied the effects of transcranial magnetic stimulation (TMS), natalizumab, dimethyl fumarate, and dexamethasone on Dark Agouti rats given a single dose of myelin oligodendrocyte glycoprotein (MOG). MOG triggered a significant increase in clinical score and in levels of lipid peroxides and carbonylated proteins, but reduced the GSH/GSSG ratio in brain, spinal cord and blood. Both TMS and the clinical treatments decreased the changes caused by MOG, with TMS doing so more significantly.
Maliszewska J et al. · 2018
Researchers studied whether a 50 Hz magnetic field affects how American cockroaches respond to noxious heat and alters oxidative stress markers. The exposure was 50 Hz at 7 mT, and the researchers measured how long cockroaches took to escape from high ambient temperature. Escape latency significantly increased after 24 hours, 72 hours, and 7 days of EMF exposure. Malondialdehyde levels increased significantly after 24-hour exposure and remained elevated up to 7 days, while glutathione levels significantly declined after 7 days of exposure.
Mahmoudinasab H, Saadat M. · 2018
Researchers measured the effects of morphine and EMF, in combination with β-lapachone, on cell growth inhibition and expression of antioxidant genes in SH-SY5Y cells. The study used 0.50 mT intensity of 50 Hz EMF under two exposure conditions: "15 min field-on/15 min field-off" and "30 min field-on continuously." Under the "15 min field-on/15 min field-off" condition, NQO1 mRNA level decreased while NQO2 expression increased. Multiple linear regression analysis indicated that NQO1 mRNA levels were associated positively with β-lapachone and negatively with EMF.
Mahmoudinasab H, Saadat M. · 2018
Researchers tested four treatment combinations on MCF-7 and SH-SY5Y cells: cisplatin alone, cisplatin with morin, cisplatin with electromagnetic field, and cisplatin combined with both morin and electromagnetic field. The electromagnetic field was applied at 50 Hz and 0.50 mT using a cycle of 15 minutes field-on followed by 15 minutes field-off. The IC50 value of cisplatin in the cisplatin-plus-morin-plus-EMF treatment was significantly higher than cisplatin alone and the cisplatin-plus-morin treatment in both cell lines. In SH-SY5Y cells, most of the antioxidant genes showed upregulation with the cisplatin-plus-EMF and cisplatin-plus-morin-plus-EMF treatments, while antioxidant gene expression patterns were similar across the four treatments in MCF-7 cells.
Hajipour Verdom B, Abdolmaleki P, Behmanesh M. · 2018
Researchers investigated the effects of a homogenous static magnetic field (SMF) on doxorubicin-induced toxicity and proliferation rate of cancer cells. SMF alone decreased cell viability and proliferation rate in MCF-7 and HFF cells, similar to doxorubicin alone. The combination of 10 mT SMF and 0.1 µM doxorubicin decreased viability and proliferation of cancer and normal cells in a synergistic manner. The findings suggest that SMF can decrease the required dose of chemotherapy drugs such as doxorubicin and thereby decrease their side effects.
Glinka M et al. · 2018
Researchers assessed the impact of static magnetic fields of different intensities on redox homeostasis in cultures of fibroblasts. Six chambers with field flux densities varying from 0.1 to 0.7 T were used in the research. ATP concentration and the generation of malondialdehyde, a marker of oxidative stress, remained stable, while the activity of superoxide dismutase and glutathione peroxidase decreased.
Errico Provenzano A et al. · 2018
Researchers studied the effects of extremely low frequency electromagnetic fields on the differentiation process of acute promyelocytic leukemia NB4 cells that were also treated with ATRA. The NB4 cells used were a cell line established from the bone marrow of a patient affected by acute promyelocytic leukemia. ELF-EMF exposure decreased cellular proliferation potential and helped ATRA-treated NB4 cells to mature. The results indicated that ELF-EMF exposure promotes ATRA-induced granulocytic differentiation of these leukemia cells.
Dinčić M et al. · 2018
Researchers exposed Wistar albino rats to upward- or downward-oriented static magnetic fields for 50 days, then measured enzyme activities and oxidative stress markers in synaptosomes isolated from the whole rat brain. Chronic exposure to 1 mT static magnetic field significantly increased ATPase and acetylcholinesterase activities, and raised malondialdehyde levels in both exposed groups compared to controls. Synaptosomal catalase activity was significantly decreased in the group exposed to the downward-oriented field compared to both the control group and the upward-oriented field group.
Consales C et al. · 2018
Coballase-Urrutia E et al. · 2018
Researchers studied the effects of static magnetic fields at 0.8 mT on oxidative stress markers in a restraint stress animal model. Exposure to static magnetic fields over 5 days at 30, 60, and 240 minutes per day decreased NO, MDA, AGEs, and AOPP levels and increased SOD and GSH levels, with the response being time-dependent.
Budziosz J et al. · 2018
Researchers exposed male Wistar rats to an electromagnetic field with a frequency of 50 Hz, intensity of 10 kV/m, and magnetic induction of 4.3 pT for 22 hours a day to evaluate oxidative stress in central nervous system structures. Mean malondialdehyde levels and total oxidant status in the CNS structures did not differ significantly between the experimental and control groups. Antioxidant enzyme activities in brain structure homogenates were decreased, with the exception of frontal cortex catalase, glutathione peroxidase, and hippocampal glutathione reductase.
Zhang J, Sumich A, Wang GY. · 2017
Researchers reviewed recent brain imaging and brain wave studies to examine whether mobile phone radiation affects brain function. They found that phone radiation appears to increase brain activity and efficiency, particularly in areas near where you hold the phone, and this increased activity was linked to faster reaction times and sleep disruption. The findings suggest the scientific question of mobile phone effects on the brain should be reopened, though the researchers note that long-term effects remain largely unstudied.
Yilmaz A et al. · 2017
Researchers exposed pregnant rats to mobile phone radiation (900 MHz) for 20 days and examined their offspring's livers 60 days after birth. The exposed animals showed significant liver damage including increased oxidative stress, elevated liver enzymes indicating injury, and visible tissue damage under the microscope. This study demonstrates that EMF exposure during pregnancy can cause lasting liver problems in offspring that persist into adulthood.
Yang M et al. · 2017
Researchers analyzed 11 studies involving over 17,000 people to examine whether cell phone use increases brain tumor risk. They found that using a phone for 10 or more years increased the odds of developing glioma (a type of brain tumor) by 44%, with the strongest association for tumors on the same side of the head where people held their phone. The risk was particularly high for low-grade gliomas, which more than doubled with long-term use.
Wang J, Su H, Xie W, Yu S. · 2017
Researchers analyzed seven studies involving thousands of people to determine whether mobile phone use increases headache risk. They found that mobile phone users were 38% more likely to experience headaches compared to non-users, with risk increasing dramatically based on daily call duration and frequency. The study shows a clear dose-response relationship: people making calls longer than 15 minutes daily had 2.5 times higher headache risk than those using phones less than 2 minutes daily.
Taheri M et al. · 2017
Researchers exposed two types of bacteria (Listeria and E. coli) to radiofrequency radiation from cell phones (900 MHz) and Wi-Fi routers (2.4 GHz) to see if it affected how well antibiotics worked against them. They found that RF exposure made these disease-causing bacteria more resistant to antibiotics, meaning the medications became less effective at killing them. This could have serious implications for treating infections, as it suggests our wireless devices might be contributing to the growing problem of antibiotic-resistant bacteria.
Sepehrimanesh M, Kazemipour N, Saeb M, Nazifi S, Davis DL · 2017
Researchers exposed rats to 900 MHz cell phone radiation for up to 4 hours daily over 30 days and analyzed protein changes in testicular tissue. They found that radiation exposure increased levels of two specific proteins by 70% - proteins that are linked to cellular stress and cancer risk. This matters because many men carry phones in their pants pockets, creating similar exposure patterns to reproductive organs.
Sato Y, Kojimahara N, Taki M, Yamaguchi N · 2017
Japanese researchers surveyed over 4,000 children and adults to understand which ear people prefer when using mobile phones. They found that children typically use their dominant hand's ear, while adults show more complex patterns - with older adults and heavy work users more likely to use their left ear. This matters because knowing which ear gets more radiation exposure helps researchers design better studies on mobile phone health effects.
Qureshi ST, Memon SA, Abassi AR, Sial MA, Bughio FA. · 2017
Pakistani researchers exposed chickpea seeds to radiation from cell phones (900 MHz) and laptops (3.31 GHz) for 24 and 48 hours to study DNA damage. They found that both devices caused genetic damage to plant cells, with laptop radiation being more harmful than cell phone radiation. The study suggests these everyday devices could potentially cause DNA damage and cancer-like changes in living tissue.
