Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.
Showing 1,014 studies (Rodent Studies)
Zhu W, Cui Y, Feng X, Li Y, Zhang W, Xu J, Wang H, Lv S. · 2016
Researchers exposed rats to 2450 MHz microwave radiation (WiFi frequency) for 6 minutes and found significant heart muscle cell death. The microwaves disrupted cellular energy production and increased harmful stress, demonstrating how brief microwave exposure can damage cardiovascular tissue through specific biological mechanisms.
Esmekaya MA et al. · 2016
Researchers exposed mice to cell phone radiation (900 MHz) before, during, and after chemically-induced seizures to study brain effects. They found that radiation exposure significantly increased oxidative damage and inflammatory markers in brain tissue compared to seizures alone. This suggests cell phone radiation may worsen brain vulnerability during neurological stress, potentially making seizure-related brain damage more severe.
Yin C, Luo X, Duan Y, Duan W, Zhang H, He Y, Sun G, Sun X · 2016
Researchers exposed rat brain cells to 50 Hz magnetic fields and found significant damage including cell death and DNA harm. However, natural compounds from lotus seed pods prevented most of this damage, suggesting magnetic fields can harm brain cells but certain antioxidants may offer protection.
Yang LL et al. · 2016
Researchers exposed rats to electromagnetic pulses (EMP) at extremely high levels and found that these exposures activated microglia, the brain's immune cells, causing inflammation. The study identified that this brain immune response happened through a specific cellular pathway called p38 MAPK, and the effects were measurable within hours of exposure. This research helps explain one biological mechanism by which electromagnetic fields might affect brain function.
Wu SX, Xu YQ, Di GQ, Jiang JH, Xin L, Wu TY · 2016
Mice exposed to static electric fields (from power lines) for 35 days showed increased superoxide dismutase activity, an enzyme that fights cell damage. This suggests their liver cells were working harder to protect against electrical stress, indicating biological effects from field exposure.
Tang R, Xu Y, Ma F, Ren J, Shen S, Du Y, Hou Y, Wang T · 2016
Researchers exposed mice with lung cancer to extremely low frequency magnetic fields (7.5 Hz, 0.4 Tesla) for 2 hours daily over 27 days and found the treatment significantly reduced tumor spread in the lungs. The magnetic fields worked by altering immune cell behavior - specifically reducing regulatory T cells (immune cells that normally suppress anti-tumor responses) and increasing cellular stress molecules called reactive oxygen species. This suggests that certain magnetic field exposures might enhance the body's natural ability to fight cancer by modifying immune system function.
Luo X et al. · 2016
Researchers exposed mice to extremely low frequency electromagnetic fields (the type from power lines and appliances) for 4 hours daily for 28 days and found it caused oxidative stress damage in their brains. However, when mice were given lotus seed extract before and during exposure, the natural antioxidants significantly protected against this cellular damage by boosting the body's natural defense systems.
Hu Y et al. · 2016
Researchers exposed mice with Alzheimer's disease to a 50 Hz magnetic field (the type from power lines) for 20 hours daily over 3 months. The magnetic field exposure improved the mice's memory and learning abilities, while also reducing toxic protein buildup in their brains that's characteristic of Alzheimer's. This suggests that certain types of electromagnetic fields might actually have protective effects on brain health rather than harmful ones.
Ansari AM et al. · 2016
Researchers exposed mice to extremely low frequency magnetic fields (the type produced by power lines and electrical devices) for either 2 hours once or 2 hours daily for 2 weeks. They found that long-term exposure actually reduced depression-like behavior in the mice, while short-term exposure had no effect. The study suggests these magnetic fields may alter brain chemistry by affecting nitric oxide levels, which plays a role in mood regulation.
Wang LF et al. · 2016
Researchers exposed rats to microwave radiation (30 mW/cm²) for 2 months and discovered that genetic variations in the brain's GRIN2B gene determine whether animals experience memory problems from the exposure. Rats with a specific genetic variant (TT genotype) showed memory impairment and brain chemistry changes after microwave exposure, while those with other variants (CC and CT) were protected from these effects.
Deshmukh PS et al. · 2016
Researchers exposed rats to cell phone radiation (900-2450 MHz) for 2 hours daily over 90 days at levels 1000 times below safety limits. The low-level radiation still impaired learning and memory while damaging brain DNA, suggesting current safety standards may be inadequate.
(E) Barthélémy A et al. · 2016
French researchers exposed rats to cell phone radiation (900 MHz) for 15-45 minutes and found that even brief exposures caused brain inflammation and memory problems. At exposure levels similar to what heavy cell phone users experience (6 W/kg), rats showed a 119% increase in brain inflammation markers and reduced long-term memory performance. The study demonstrates that radiofrequency radiation can trigger inflammatory responses in the brain that directly impact cognitive function.
Malkemper EP et al. · 2015
Researchers tested whether wood mice can sense magnetic fields by observing where they built nests in circular arenas. They found that mice normally oriented their nests north-south using Earth's magnetic field, but when exposed to weak radio frequency fields (0.9-5 MHz), the mice switched to building nests east-west instead. This demonstrates that low-level RF exposure can disrupt an animal's natural magnetic navigation system.
Gurbuz N, Sirav B, Kuzay D, Ozer C, Seyhan N. · 2015
Researchers exposed diabetic rats to cell phone radiation (2100 MHz) to see if it caused genetic damage in bladder cells by looking for micronuclei - small fragments of broken DNA that indicate cellular damage. They found no increase in genetic damage in either healthy or diabetic rats exposed to the radiation compared to unexposed animals. The study suggests that this level of RF radiation may not cause DNA damage in bladder cells, even in animals with diabetes who might be more vulnerable.
Court-Kowalski S et al. · 2015
Researchers exposed mice to cell phone radiation (900 MHz) at high levels (4 W/kg SAR) for five days per week over two full years, then examined their brains for signs of astrocyte activation - a cellular response that indicates brain injury or stress. They found no detectable changes in these protective brain cells compared to unexposed mice, suggesting this level of radiofrequency exposure did not trigger measurable brain inflammation or damage.
Zhang Y, Liu X, Zhang J, Li N. · 2015
Researchers exposed rats to extremely low frequency electromagnetic fields (the type emitted by power lines and electrical devices) for 12 weeks to see if it would affect memory and brain health, particularly markers associated with Alzheimer's disease. They found no changes in the rats' memory performance, brain tissue structure, or levels of amyloid-beta proteins that are linked to Alzheimer's. This suggests that short-term exposure to these fields at the levels tested did not harm cognitive function in this animal model.
Nazıroğlu M, Özkan FF, Hapil SR, Ghazizadeh V, Çiğ B. · 2015
Researchers exposed brain cells from epileptic rats to 900 MHz cell phone radiation for one hour to see if it would worsen brain damage. While epilepsy itself caused significant cellular damage including cell death and calcium influx, the cell phone radiation did not add any additional harmful effects. This suggests that 900 MHz EMF exposure may not exacerbate existing brain conditions like epilepsy.
Duan W et al. · 2015
Researchers exposed mouse sperm cells to two types of electromagnetic fields - 50 Hz extremely low frequency (like power lines) and 1800 MHz radiofrequency (like cell phones) - to compare DNA damage. They found that high-intensity ELF fields caused DNA strand breaks, while high-intensity RF fields caused oxidative DNA damage through different mechanisms. The study suggests both types of EMF can damage DNA at high exposure levels, but through distinct biological pathways.
Salunke BP, Umathe SN, Chavan JG. · 2015
Researchers exposed mice to 2.45 GHz radiofrequency radiation (the same frequency used by WiFi and Bluetooth) for up to 120 days to see if it would cause anxiety, obsessive-compulsive behaviors, or depression-like symptoms. The study found no behavioral changes in the mice across multiple standard tests, even after four months of daily exposure. This suggests that chronic exposure to this common wireless frequency may not directly affect mood or anxiety-related behaviors.
Nazıroğlu M, Ozkan FF, Hapil SR, Ghazizadeh V, Ciğ B · 2015
Researchers exposed brain cells from epileptic rats to 900 MHz mobile phone radiation for one hour to see if it worsened seizure-related brain damage. The epilepsy itself caused significant cell death, oxidative stress, and calcium influx in the hippocampus (a brain region crucial for memory), but the mobile phone radiation didn't add any additional harmful effects. This suggests that in already-damaged brain tissue, 900 MHz EMF exposure may not worsen the cellular damage beyond what the disease itself causes.
Shokri S, Soltani A, Kazemi M, Sardari D, Mofrad FB. · 2015
Researchers exposed male rats to Wi-Fi radiation (2.45 GHz) for either 1 hour or 7 hours daily over 2 months to study effects on fertility. Both exposure groups showed decreased sperm quality, increased cell death in the testes, and reduced seminal vesicle weight compared to unexposed rats, with longer exposures causing more severe damage. This suggests that common Wi-Fi frequencies may harm male reproductive health in a dose-dependent manner.
Sehitoglu I et al. · 2015
Researchers exposed pregnant rats to 900 MHz cell phone radiation for 24 hours daily during pregnancy, then examined the reproductive health of their male offspring at 60 days old. The exposed rats had 13% lower testosterone levels, smaller testes, and increased cell death markers compared to unexposed controls. This suggests that cell phone radiation exposure during pregnancy may harm the developing reproductive system of male offspring.
Saygin M, Asci H, Ozmen O, Cankara FN, Dincoglu D, Ilhan I · 2015
Researchers exposed young male rats to 2.45 GHz microwave radiation (the same frequency as WiFi and Bluetooth) for 3 hours daily over 30 days and found significant damage to testicular tissue and sperm production. The radiation increased oxidative stress markers and inflammatory proteins while reducing sperm counts in the testes. However, when rats were given gallic acid (an antioxidant found in tea and berries), it largely prevented these reproductive damages.
Sangun O, Dundar B, Darici H, Comlekci S, Doguc DK, Celik S · 2015
Researchers exposed pregnant and newborn female rats to WiFi-frequency radiation (2450 MHz) for one hour daily and tracked their development through puberty. Rats exposed in the womb showed slower growth, delayed puberty, and increased oxidative stress in brain and ovary tissues compared to unexposed controls. This suggests that WiFi radiation during critical developmental periods may disrupt normal reproductive maturation.
Şahin A et al. · 2015
Researchers exposed young rats (equivalent to pre-adolescent humans) to 900-MHz cell phone radiation for one hour daily over 30 days, then examined their brain tissue. They found significant loss of pyramidal neurons in the hippocampus (a brain region crucial for memory and learning) and observed damaged cells with abnormal appearance. This suggests that cell phone radiation exposure during development may harm critical brain cells needed for cognitive function.