Browse 6,486 peer-reviewed studies on electromagnetic field health effects from 4 research libraries.
Showing all 6,486 studies
Goraca A, Ciejka E, Piechota A. · 2010
Researchers exposed rats to an extremely low frequency magnetic field (ELF-MF) at 40 Hz and 7 mT for either 30 or 60 minutes per day for 14 days, then measured oxidative stress markers in heart tissue and plasma. Exposure at 30 minutes per day did not significantly alter any of the measured oxidative stress markers.
Garip AI, Akan Z. · 2010
Researchers investigated the effect of ELF-EMF on apoptosis in K562 human leukemia cells, with and without oxidative stress, and examined links to heat-shock protein 70 levels. ELF-EMF at 1 mT and 50 Hz was applied for 3 hours, with one group of cells treated with H2O2 to induce oxidative stress and another left untreated. In cells not exposed to oxidative stress, ELF-EMF caused a decrease in the number of apoptotic cells and a slight increase in viability. In cells treated with H2O2, ELF-EMF increased the number of apoptotic cells, and hsp70 and reactive oxygen species levels were also increased.
Frahm J, Mattsson MO, Simkó M. · 2010
Researchers exposed mouse macrophages to a 50 Hz, 1.0 mT magnetic field and measured changes in reactive oxygen species production and protein expression. Short-term exposures of two hours or less caused slight and transient decreases in several proteins, including clathrin, adaptin, PI3-kinase, protein kinase B, and PP2A, while longer exposures had no effect on these proteins. The stress proteins Hsp70 and Hsp110 showed increased levels at certain time points but not generally.
Ciejka E, Skibska B, Kleniewska P, Goraca A. · 2010
Researchers studied the influence of a low-frequency magnetic field on oxidative stress markers in rat muscles. Thirty male rats weighing 280 to 300 grams were randomly divided into three experimental groups, each containing seven animals. One treatment group was exposed to 40 Hz and 7 mT for 0.5 hours per day for 14 days, and the other was exposed at the same settings for 1 hour per day for 14 days. Exposure caused a significant increase in sulfhydryl group concentration and a decrease in protein concentration in the muscle homogenates.
Ayşe IG, Zafer A, Sule O, Işil IT, Kalkan T. · 2010
Researchers studied the effect of ELF-EMF on the differentiation of K562 cells at different time courses. A single exposure to ELF-EMF resulted in a decrease in differentiation, while ELF-EMF applied every day for 1 hour caused an increase in differentiation. ELF-EMF increased ROS levels in K562 cells not treated with hemin, but did not change ROS levels in hemin-treated cells, indicating that ROS was not the cause of the differentiation effects.
Akan Z, Aksu B, Tulunay A, Bilsel S, Inhan-Garip A · 2010
Researchers applied 50 Hz, 1 mT electromagnetic fields for 4 to 6 hours to human monocytic leukemia cells (THP-1) that had been stimulated with Staphylococcus aureus or interferon gamma/lipopolysaccharide. Field application increased nitric oxide levels, with the increase appearing earlier and being more prominent in cells stimulated with S. aureus. ELF-EMF alone caused increased hsp70 levels in a time-dependent manner, and the growth curve of exposed bacteria was lower than the control. The researchers suggested that ELF-EMF could be exploited for beneficial uses.
Szemerszky R, Zelena D, Barna I, Bárdos G. · 2010
Researchers exposed adult male Sprague-Dawley rats to 50 Hz electromagnetic fields at 0.5 mT, either for 5 days at 8 hours daily or for 4 to 6 weeks at 24 hours daily. Neither exposure duration produced the body changes associated with chronic stress, such as body weight reduction, thymus involution, or adrenal gland hypertrophy. After long-term exposure, rats showed elevated proopiomelanocortin and depressive-like behavior, and blood glucose was also higher. The researchers noted that the exposure intensity used was much higher than typical human exposure.
Sun H, Che Y, Liu X, Zhou D, Miao Y, Ma Y. · 2010
Researchers investigated memory impairment in newly hatched chicks following in ovo exposure to a 50-Hz magnetic field of 2 mT for 60 minutes per day on embryonic days 12 through 18. Memory retention was tested at 10, 30, and 120 minutes after exposure to a bitter-tasting bead.
Ravera S et al. · 2010
Researchers investigated how extremely low frequency magnetic fields affect acetylcholinesterase (AChE) activity in synaptosomal membranes from the cerebellum. Sinusoidal 50 Hz fields at different amplitudes caused AChE activity to decrease about 27%, with a threshold of about 0.74 mT. The decrease was completely reversible and independent of the time spent in the field. When the synaptosomal membranes were solubilized with Triton, the fields did not affect AChE activity, suggesting the membrane plays a crucial role in the effect.
Kumar S, Jain S, Behari J, Avelev VD, Mathur R. · 2010
Researchers studied the effect of magnetic field exposure on food intake, water intake, and body weight in rats with complete spinal cord injury. Exposure ran at 50 Hz and 17.9 T for 2 hours per day over 8 weeks in rats with complete spinal cord transection at the T13 level. The results suggest a significant beneficial effect of chronic exposure to magnetic field of paraplegic rats.
Gulturk S et al. · 2010
Rats in the magnetic field groups were exposed to a 5 mT field for 165 minutes every day for 30 days, and all rats underwent Evans blue measurement to evaluate the blood-brain barrier. Diabetes and magnetic field exposure each increased blood-brain barrier permeability, their combination caused a greater increase, and insulin reduced that effect.
Cuccurazzu B et al. · 2010
The exposure significantly enhanced neurogenesis in the dentate gyrus, with increased numbers of cells labeled for markers of new and developing neurons. Roughly half of the newly generated neurons survived 30 days after stimulation and became mature neurons integrated into the granule cell layer. The new mature neurons were associated with increased long-term potentiation, indicating an influence on hippocampal synaptic plasticity.
Carrubba S, Frilot C 2nd, Chesson AL Jr, Marino AA · 2010
Researchers recorded EEGs from six standard locations in 20 volunteers to detect brain potentials triggered by a pulse of the type produced by mobile phones. Evoked potentials having the expected latency were found in 90% of the volunteers, as assessed using a nonlinear method of EEG analysis. Evoked potentials were not detected when the EEG was analyzed using time averaging. The possibility of systematic error was excluded by sham-exposure analyses.
Akdag MZ, Dasdag S, Ulukaya E, Uzunlar AK, Kurt MA, Taşkin A · 2010
Researchers exposed rats to extremely low-frequency magnetic fields for 2 hours per day for 10 months, then measured apoptosis and oxidative stress markers in brain tissue. Apoptosis scores and MPO activity were not significantly different between the exposed and sham groups. MDA, TOS, and OSI values were found to be higher in the ELF-500 group than in the ELF-100 and sham groups, and total antioxidative capacity was lower in the ELF-500 group.
Yang X, He G, Hao Y, Chen C, Li M, Wang Y, Zhang G, Yu Z · 2010
Researchers studied how electromagnetic field exposure affects N9 microglial cells and the role of the JAK2-STAT3 signaling pathway in any resulting pro-inflammatory responses. EMF significantly induced phosphorylation of JAK2 and STAT3, and also dramatically increased the expression of CD11b, TNF-α, and iNOS, and the production of NO. When cells were pretreated with the JAK inhibitor P6, phosphorylation of JAK2 and STAT3 was strongly suppressed, and expression of CD11b, TNF-α, and iNOS was suppressed at 12 hours but not at 3 hours after EMF exposure.
Sonmez OF, Odaci E, Bas O, Kaplan S · 2010
Researchers exposed 16-week-old adult female rats to 900 MHz EMF for 1 hour per day for 28 days and then counted Purkinje cells in the cerebellum using a stereological technique. The total number of Purkinje cells in the exposed group was significantly lower than in both the control group (p < 0.004) and the sham-exposed group (p < 0.002). Body and brain weights did not differ significantly between the exposed and unexposed groups.
Rağbetli MC et al. · 2010
Researchers investigated the effect of mobile phone exposure on Purkinje and granule neurons in the developing cerebellum. Pregnant Swiss albino mice were exposed to GSM mobile phone radiation at 890–915 MHz at 0.95 W/Kg specific absorption rate (SAR). The study found a significant decrease in the number of Purkinje cells and a tendency for granule cells to increase.
Maskey D et al. · 2010
Researchers investigated the effect of 835-MHz radiofrequency exposure on rat hippocampus for 3 months using immunohistochemical methods. A decrease in calbindin immunoreactivity was observed in the exposed group, with loss of interneurons and pyramidal cells in the CA1 area and loss of granule cells. An overall increase in GFAP immunoreactivity was observed in the hippocampus of exposed rats, and apoptotic cells were detected in the CA1, CA3 areas and dentate gyrus.
Maskey D et al. · 2010
Researchers measured calbindin (CB) and calretinin (CR) expression in the hippocampus of mice after exposure to 835 MHz electromagnetic fields at various durations and absorption rates. Exposure conditions included 1 hour per day for 5 days at a specific absorption rate of 1.6 W/kg, 1 hour per day for 5 days at 4.0 W/kg, 5 hours per day for 1 day at 1.6 W/kg, 5 hours per day for 1 day at 4.0 W/kg, and daily exposure for 1 month at 1.6 W/kg. Exposure for 1 month produced almost complete loss of pyramidal cells in the CA1 area. Body weights did not change significantly across the exposure groups.
Söderqvist F, Hardell L, Carlberg M, Mild KH · 2010
Researchers proposed that transthyretin (TTR), a protein that sequesters amyloid-beta, might help explain findings related to radiofrequency exposure and Alzheimer's disease. In a provocation study on 41 persons exposed for 30 minutes to an 890-MHz GSM signal at 1.0 Watt/kg to the temporal area of the brain, serum TTR was found to be statistically significantly increased 60 minutes after exposure. In a cross-sectional study on 313 subjects, a statistically significantly positive association was found between serum TTR and time since first use of mobile phones and desktop cordless phones combined (P=0.03).
Imge EB, Kiliçoğlu B, Devrim E, Cetin R, Durak I · 2010
Forty female rats were divided into four groups: control, mobile phone, mobile phone plus vitamin C, and vitamin C alone. The mobile phone groups were exposed to a mobile phone signal (900 MHz), and vitamin C was administered orally for four weeks. Mobile phone exposure caused an inhibition in 5'-NT and CAT activities compared to the control group, while GSH-Px activity and MDA levels were reduced but not significantly. The researchers suggested that vitamin C may play a protective role against detrimental effects of mobile phone radiation in brain tissue.
Hao Y, Yang X, Chen C, Yuan-Wang, Wang X, Li M, Yu Z · 2010
Researchers exposed murine N9 microglial cells to 2.45 GHz electromagnetic fields and examined several molecular markers of cell activation. After exposure, a significant increase of STAT3 DNA-binding ability was noted, and EMF rapidly induced phosphorylation of STAT3 and activated JAK1 and JAK2. Transcription levels of the inflammation-associated genes iNOS and TNF-alpha also increased after EMF exposure. When a JAK inhibitor called P6 was applied, it reduced induction of iNOS and TNF-alpha, nuclear factor binding activity, and activation of STAT3 in EMF-stimulated microglia.
Fragopoulou AF et al. · 2010
Researchers tested the effects of mobile phone radiation on spatial learning and memory in mice using the Morris water maze, a hippocampal-dependent spatial memory task. The mice received a 2 h daily dose of pulsed GSM 900 MHz radiation from a commercially available mobile phone for 4 days at SAR values ranging from 0.41 to 0.98 W/kg. Exposed animals showed a deficit in transferring acquired spatial information across training days, with increased escape latency and distance swam compared to sham-exposed animals. During the memory probe trial, sham-exposed animals showed the expected preference for the target quadrant, while exposed animals showed no preference.
Croft RJ et al. · 2010
Researchers tested whether adolescents and the elderly are more sensitive to mobile phone-related bioeffects than young adults, using both 2G GSM and 3G W-CDMA exposures. Resting alpha activity in the 8-12 Hz band of the EEG was recorded and compared between conditions in a double-blind crossover design, with each participant receiving sham, 2G, and 3G exposures separated by at least 4 days. Young adults showed greater alpha activity in the 2G condition compared to sham, but no effect was found in adolescents or the elderly, and 3G exposure produced no effect in any group.
Bak M, Dudarewicz A, Zmyślony M, Sliwinska-Kowalska M · 2010
Researchers assessed the effect of electromagnetic field from the GSM mobile phone system on human brain function in volunteers. The assessment was based on event related potentials, with P300 latency, amplitude, and latency of the N1, N2, P2 waves analysed. The statistical analysis revealed an effect of EMF on P300 amplitude, with lower amplitudes observed only during exposure. No statistically significant changes were noted in the latencies of the N1, N2, P2 waves or in the latency of the P300 itself.