6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 6,486 peer-reviewed studies on electromagnetic field health effects from 4 research libraries.

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From subsea power cable to small-spotted catshark Scyliorhinus canicula: Behavioural effects of electromagnetic fields in tank experiments

Hermans A et al. · 2025

Researchers studied the effects of electromagnetic fields on the swimming behaviour of 14 individual small-spotted catsharks Scyliorhinus canicula. All sharks were exposed to field-relevant EMF gradients in three trials: 15.0 μT AC, 19.6 μT DC, and a control treatment. Sharks showed no startle response to EMF onset, did not alter movement towards or away from the cable, and crossed it as frequently as in control trials. Hidden Markov Models showed that behavioural states were best explained by EMF treatment, trial order and sex. Sharks showed 25% less time transiting during DC trials when compared to AC and control trials.

Brain & Nervous SystemNo Effects Found

Examining the effects of extremely low- frequency magnetic fields on cognitive functions and functional brain markers in aged mice

Unknown authors · 2025

Researchers exposed aged mice to 50 Hz ELF-MF at 1 mT for 8 hours per day, 5 days per week for 12 weeks. Sham-exposed aged mice showed a significant age-related decline in spatial memory compared to young adult mice. Chronic ELF-MF exposure did not worsen this memory decline or change hippocampal levels of APP-695, Aβ(1−42), S100b, GFAP, or the pTau/Tau ratio.

Learned magnetic map cues and two mechanisms of magnetoreception in turtles

Unknown authors · 2025

Researchers fed juvenile loggerhead turtles repeatedly in magnetic fields replicating particular oceanic locations. The turtles learned to distinguish magnetic fields where they encountered food from fields that exist elsewhere. Conditioned responses in the magnetic map assay were unaffected by radiofrequency oscillating magnetic fields, while orientation behavior requiring the magnetic compass was disrupted by such fields.

Can Theta Burst Electromagnetic Fields Disrupt Learning in Planaria? Evidence of Impaired Fear-Conditioned Responses

Unknown authors · 2025

Researchers exposed planaria to a theta burst electromagnetic field of 1 μT intensity and 100 Hz bursts in a T-maze with an aversive light stimulus. Planaria that received only the light stimulus learned to avoid the associated maze arm, shown by a significant decrease in preferred arm selections. Planaria exposed to the electromagnetic field before or after light exposure did not show this learning, as their arm selections remained stable.

Intermittent ELF-MF exposure effectively ameliorates pathologic features associated with adult AD mice

Geng D, Liu A, Yan Y, Zheng W · 2025

ELF-MF stimulation improved spatial working memory in the AD model mice. Local field potential analysis showed that AD reduced theta and gamma band energy in the hippocampal CA1 region, while ELF-MF stimulation significantly enhanced this energy. Immunofluorescence detection revealed that ELF-MF stimulation reduced abnormal accumulation of Aβ42 and Drp1 in the hippocampus, with intermittent stimulation showing a more significant effect in adult mice.

Increased Expression of Bacterial Cellulose Synthase Genes in Komagataeibacter Xylinus Exposed to a Rotating Magnetic Field

Zywicka A, Dunisławska A, Fijalkowski K · 2025

K. xylinus cells were subjected to a rotating magnetic field at frequencies of 5 and 50 Hz for durations ranging from 12 to 72 h. Gene expression was assessed using quantitative polymerase chain reaction. RMF exposure significantly enhanced BC production efficiency, with average wet and dry BC yields increasing by 28% and 18% and upregulated bcs gene expression showing statistically significant changes at both frequencies and all time points, the strongest effects at 5 Hz.

Pulsed electromagnetic fields mediate sensory nerve regulation for bone formation in aging models

Unknown authors · 2025

The study found that PEMFs increased new bone formation and nerve innervation, promoting osteogenesis and reducing adipogenesis in MSCs of aging male mice. PEMF-induced osteogenesis was impaired when sensory nerves were dysfunctional. PEMFs stimulated sensory nerves to secrete Sema3A, which acted through the Nrp1 receptor on leptin-receptor-expressing MSCs to drive osteogenesis, inhibit adipogenesis, and counteract cellular senescence. Depleting sensory nerves or knocking out Sema3A or Nrp1 abolished the bone-forming effects of PEMFs.

Whole Body / General5,364 citations

Extremely low-frequency electromagnetic fields facilitate proliferation and functional differentiation in spinal neural stem cells

Tang W, He D, Li X, Feng Y, Xu Y, Hu J, Xu W, Xue L · 2025

Researchers used spinal cord-derived neural stem cells from adult mice to study the effects of extremely low-frequency electromagnetic fields. ELF-EMFs enhanced cell proliferation and self-renewal by upregulating Sox2 expression. ELF-EMFs activated T-type calcium channels and enhanced calcium currents. Increased intercellular calcium concentration upregulated NeuroG1 and NeuroD1 expression, promoting neuronal differentiation of NSCs and enhancing neurite outgrowth.

Fifty-hertz magnetic fields induce DNA damage through activating mPTP associated mitochondrial permeability transition in senescent human fetal lung fibroblasts

Sun C, Wang S, Zhang J, Zhou X, Zhu T, Mao G · 2025

Researchers exposed senescent and non-senescent human fetal lung fibroblasts to 50 Hz magnetic fields at 1.0 mT for 24 h. Further results showed that reactive oxygen species generation mediated by mitochondrial permeability transition pore activation play critical role in this process. The authors concluded that cellular senescence can lead to cell sensitivity to the DNA damage effect of 50 Hz MFs, however, whether this play important role in mediating the carcinogenesis of EMFs await further study.

Pulsed Electromagnetic Field Therapy Alters the Genomic Profile of Bladder Cancer Cell Line HT-1197

Unknown authors · 2025

Researchers cultured HT-1197 bladder cancer cells and exposed them to PEMF therapy for one hour each day for five days. Cells were exposed to PEMF therapy for one hour each day for five days, and proliferation rates were measured using Incucyte data. HT-1197 cells treated with PEMF therapy showed slower proliferation compared to controls, while a different bladder cancer cell line HT-1376 did not show this effect. Gene expression analysis at days 1 and 5 revealed altered expression of numerous genes and cancer-related pathways in treated cells. Principal component analysis showed complete separation of treated and untreated cells, with PEMF treatment accounting for 76% of the variation.

Transcriptomic profiling of human mesenchymal stem cells using a pulsed electromagnetic-wave motion bioreactor 143 system for enhanced osteogenic commitment and therapeutic potentials

Randhawa A, Ganguly K, Dutta SD, Patil TV, Lim K-T · 2025

Researchers used a pulsed electromagnetic field wave-motion bioreactor to culture human bone marrow-derived mesenchymal stem cells. A 30-minute exposure at 10V, 1Hz, 5.82 G with 35 oscillations per minute increased cell proliferation from 1 × 105 to 4.5 × 105 compared to static culture. In osteo-induction media, the dynamic pulsed electromagnetic field enhanced osteogenic transcription factors and shifted osteogenic and signaling genes. The combined wave and pulsed electromagnetic field stimulation also induced ROS-scavenging properties in the cells.

Decreasing Bone Resorption by Inducing Anti-Osteoclastogenic IFN-γ and IL-10 Expression in the Spleen Through an Electromagnetic Field on LPS-Induced Osteoporosis Mice

Unknown authors · 2025

Researchers divided 40 mice into four groups to evaluate whether pulsed electromagnetic field (PEMF) therapy could inhibit bone resorption in a mouse model of lipopolysaccharide (LPS)-induced osteoporosis. Spleen tissue analysis demonstrated significant upregulation of IFN-γ and IL-10 expression in the PEMF group. Micro-CT and histological analysis confirmed that PEMF inhibited femoral bone loss and promoted bone regeneration in calvarial defects.

Pulsed electromagnetic fields modulate energy metabolism during wound healing process: an in vitro model study

Unknown authors · 2025

The researchers used scratch-wound healing and cell viability assays to test how PEMFs affect L929 fibroblast migration and survival. Exposure to PEMFs at 4 mT and 80 Hz increased cell migration and viability. Seahorse glycolysis and mitochondrial stress tests showed that exposed cells became highly glycolytic, while intracellular acidification rose and ROS levels stayed low. More vesicles were generated and transported toward the nucleus in PEMF-treated L929 cells. The authors concluded that PEMFs reprogram fibroblast metabolism from mitochondrial respiration to glycolysis and boost vesicular transport, linking these changes to wound healing.

Effects of moderate static magnetic fields on voltage-gated potassium ion channels in sympathetic neuron-like PC12 cells

Kaneda E, Kawai T, Okamura Y, Miyagawa S · 2025

Researchers investigated the effects of moderate static magnetic fields on Kv channels in sympathetic neuron-like PC12 cells. After 18 hours of exposure, Kv channel current density was significantly lower in the exposed group, and the effect persisted after magnet removal. RNA sequencing identified 37 SMF-sensitive genes, and gene expression changes suggested pathways inhibiting neuronal excitability may be more likely activated.

Alleviation of Inflammatory Conditions Caused by Extremely Low-Frequency Electromagnetic Field Exposure by Panax ginseng

Unknown authors · 2025

Electronic devices such as cellphones, microwaves, and other household devices are known to emit electromagnetic waves, creating an environment that may disrupt homeostasis. Ginsenosides in red ginseng are known for anticancer, anti-inflammatory, and antidiabetic properties. The study aims to assess the therapeutic properties of ginsenosides in extremely low-frequency electromagnetic field exposure.

Investigating the expression changes of several key genes in prostate cancer cells under exposure to the ELF pulsed electromagnetic fields

Unknown authors · 2025

Researchers cultured DU-145 prostate cancer cells and exposed them to ELF P-EMF at different intensities and durations. Cell viability was measured with the MTT assay and apoptosis and necrosis were analyzed by flow cytometry. Increasing the field intensity from 22.6 to 35 mT and prolonging exposure significantly increased cancer cell mortality and could induce apoptosis. The treatment significantly increased PTEN expression, increased BAX expression, significantly reduced MIR-21 expression, and partially reduced BCL-2 expression.

Exposure of Sprague Dawley Rats to Phone Cell Electromagnetic Field Frequency and Related Physiological, Apoptotic and Molecular Profile of Para Oral Tissues: In-vivo Study

Abdel Rahman GAN, Mohamed AF · 2025

Exposure of senile, adult, and young rats to cellular EMF increased ROS and MDA and decreased SOD. Avocado administration customized the oxidative stress changes, and EMF-avocado groups showed almost normalization of oxidative stress compared with controls. Apoptosis and necrosis were highest in senile rats, followed by young and adult rats, while parotid gland tissue resisted EMF effects.

Effect of ELF-EMF on cognitive functions, analgesia, and oxidative stress in rats with PTZ-induced epilepsy

Gülmez K, Demirkazık A, Taşkıran AŞ · 2025

Twenty-four Wistar albino male rats were divided into sham, EMF, PTZ, and EMF+PTZ groups and exposed to alternating 50-Hz and 5-mT EMF for 165 min a day for 7 days while epileptic seizures were induced with PTZ. A statistically significant difference was observed in learning and short-term memory between the EMF+PTZ group and the PTZ group. Analgesia latency statistically significantly increased in the ELF-EMF and ELF-EMF+PTZ groups compared with both the control and epilepsy groups. TOS increased in the prefrontal cortex of the PTZ group versus sham, increased in the hippocampus of both PTZ and ELF-EMF+PTZ groups versus sham, and ELF-EMF decreased the hippocampal TOS increase in the PTZ group.

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